Search Results - "Dusan Sokolovic"
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Gentamicin nephrotoxicity in animals: Current knowledge and future perspectives
Published in EXCLI journal (01-01-2017)“…Due to high relative blood flow the kidney is prone to drug-induced damage. Aminoglycoside type antibiotic gentamicin is one of the leading cause of…”
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Melatonin arrests excessive inflammatory response and apoptosis in lipopolysaccharide-damaged rat liver: A deeper insight into its mechanism of action
Published in Tissue & cell (01-12-2022)“…Sepsis is a life-threatening organ dysfunction. An animal model mimicking sepsis utilizes lipopolysaccharide (LPS), an endotoxin recognized as the most potent…”
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Oregano ( Origanum vulgare ) Essential Oil and Its Constituents Prevent Rat Kidney Tissue Injury and Inflammation Induced by a High Dose of L-Arginine
Published in International journal of molecular sciences (01-01-2024)“…This study aimed to evaluate the protective action of oregano ( ) essential oil and its monoterpene constituents (thymol and carvacrol) in L-arginine-induced…”
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Melatonin as a Promising Anti-Inflammatory Agent in an In Vivo Animal Model of Sepsis-Induced Rat Liver Damage
Published in International journal of molecular sciences (29-12-2023)“…Melatonin (MLT), earlier described as an effective anti-inflammatory agent, could be a beneficial adjunctive drug for sepsis treatment. This study aimed to…”
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Melatonin Mediates Cardiac Tissue Damage under Septic Conditions Induced by Lipopolysaccharide
Published in International journal of molecular sciences (15-10-2024)“…Lipopolysaccharide (LPS) is known to induce oxidative stress and inflammation, leading to significant damage in cardiac tissues. This study investigates the…”
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Pre- vs. post-treatment with melatonin in CCl4-induced liver damage: Oxidative stress inferred from biochemical and pathohistological studies
Published in Life sciences (1973) (01-06-2018)“…The present study was designed to compare the ameliorating potential of pre- and post-treatments with melatonin, a potent natural antioxidant, in the carbon…”
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Comparison between the effects of selenomethionine and S-adenosylmethionine in preventing cholestasis-induced rat liver damage
Published in Amino acids (01-05-2019)“…We aimed to evaluate whether two methionine-related compounds, S -adenosylmethionine (SAM), and selenomethionine (SM), could lessen liver damage induced by…”
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8
Relationship between the Manner of Mobile Phone Use and Depression, Anxiety, and Stress in University Students
Published in International journal of environmental research and public health (08-04-2018)“…: There is insufficient evidence regarding the potential risk of mobile phone use on mental health. Therefore, the aim of this research was to examine the…”
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Monte Carlo optimization based QSAR modeling, molecular docking studies, and ADMET predictions of compounds with antiMES activity
Published in Structural chemistry (01-12-2023)“…The paper deals with quantitative structure–activity relationship (QSAR) modeling-based Monte Carlo optimization. The molecular descriptors involve the local…”
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10
The Influence of Removable Complete Denture on Pro‐Oxidant Antioxidant Balance and Redox‐Sensitive Inflammation Biomarker NF‐ĸB in the Oral Cavity: An Interventional Follow‐Up Study
Published in Clinical and experimental dental research (01-10-2024)“…ABSTRACT Objectives Oxidative stress, an imbalance between the body's natural antioxidant defenses and the production of reactive oxygen species (ROS), can…”
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11
Exogenous putrescine affects polyamine and arginine metabolism in rat liver following bile ductus ligation
Published in Canadian journal of physiology and pharmacology (01-12-2018)“…Rat bile duct ligation (BDL) represents a useful method that mimics obstructive extrahepatic cholestasis, which is known to be a frequent disorder in humans…”
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Melatonin inhibits apoptosis and oxidative tissue damage in cisplatin-induced pulmonary toxicity in rats
Published in Archives of medical science (01-01-2024)“…Cisplatin is one of the most frequently used chemotherapeutics, which is known to cause both tumor and normal lung tissue damage through the generation of free…”
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Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin
Published in Canadian journal of physiology and pharmacology (01-05-2020)“…Application of cisplatin (CP) for the treatment of different cancers is known to cause pancreatitis through an increase in reactive oxygen species production…”
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Thymol regulates the functions of immune cells in the rat peritoneal cavity after l-arginine-induced pancreatitis
Published in Life sciences (1973) (01-09-2021)“…The present study aimed to evaluate the protective action of thymol towards l-arginine-induced acute pancreatitis (AP) by studying the function of rat…”
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Protective effects of anthocyanins from bilberry extract in rats exposed to nephrotoxic effects of carbon tetrachloride
Published in Chemico-biological interactions (01-05-2019)“…This study examined the nephroprotective effects of 15 different anthocyanins from the bilberry extract on the acute kidney injury caused by CCl4. The acute…”
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Clinical indices and biomarkers for perioperative cardiac risk stratification: an update
Published in Minerva anestesiologica (01-04-2017)“…European Society of Cardiology (ESC)/ European Society of Anesthesiology (ESA) highlighted that anesthesiologist has a leading role in perioperative…”
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Antioxidant and proapoptotic effects of anthocyanins from bilberry extract in rats exposed to hepatotoxic effects of carbon tetrachloride
Published in Life sciences (1973) (15-07-2016)“…The aim of this research was to determine the hepatoprotective effects of anthocyanins from bilberry extract in rats exposed to carbon tetrachloride (CCl4) by…”
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18
QSAR Modeling of Sphingomyelin Synthase 2 Inhibitors for Their Potential as Anti-Atherosclerotic Agents
Published in Acta chimica Slovenica (01-01-2024)“…Sphingomyelin synthase 2 (SMS2) has emerged as a promising target for atherosclerosis threatment. However, the availability of selective SMS2 inhibitors and…”
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Low dose of carvacrol prevents rat pancreas tissue damage after L-arginine application, while higher doses cause pancreatic tissue impairment
Published in Food and chemical toxicology (01-06-2019)“…Carvacrol (5-isopropyl-2-methylphenol) is a biologically active monoterpene phenol abundantly present in the essential oils of many Lamiaceae…”
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Exposomic Fingerprint in the Development of Diseases: The Role of Free Radicals and Multiomics
Published in Oxidative medicine and cellular longevity (2022)“…[...]by using a linear regression model, they documented that hypertension, anosmia, ageusia, the O2−level, and the duration at the ICU may be predictors of…”
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