Search Results - "Dusak, Jill E"

Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models by Zhu, Xinmei, Nishimura, Fumihiko, Sasaki, Kotaro, Fujita, Mitsugu, Dusak, Jill E, Eguchi, Junichi, Fellows-Mayle, Wendy, Storkus, Walter J, Walker, Paul R, Salazar, Andres M, Okada, Hideho

“…Toll-like receptor (TLR)3 ligands serve as natural inducers of pro-inflammatory cytokines capable of promoting Type-1 adaptive immunity, and TLR3 is abundantly…”
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Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response : Critical roles of IFN-inducible protein-10 by NISHIMURA, Fumihiko, DUSAK, Jill E, EGUCHI, Junichi, XINMEI ZHU, GAMBOTTO, Andrea, STORKUS, Walter J, OKADA, Hideho

“…The development of effective immunotherapeutic strategies for central nervous system (CNS) tumors requires a firm understanding of factors regulating the…”
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EphA2 as a Glioma-Associated Antigen: A Novel Target for Glioma Vaccines by Hatano, Manabu, Eguchi, Junichi, Tatsumi, Tomohide, Kuwashima, Naruo, Dusak, Jill E., Kinch, Michel S., Pollack, Ian F., Hamilton, Ronald L., Storkus, Walter J., Okada, Hideho

“…EphA2 is a receptor tyrosine kinase, is frequently overexpressed in a wide array of advanced cancers. We demonstrate in the current study that the EphA2…”
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Epidermal growth factor receptor-transfected bone marrow stromal cells exhibit enhanced migratory response and therapeutic potential against murine brain tumors by Sato, Hidemitsu, Kuwashima, Naruo, Sakaida, Tsukasa, Hatano, Manabu, Dusak, Jill E, Fellows-Mayle, Wendy K, Papworth, Glenn D, Watkins, Simon C, Gambotto, Andrea, Pollack, Ian F, Okada, Hideho

“…We have created a novel cellular vehicle for gene therapy of malignant gliomas by transfection of murine bone marrow stroma cells (MSCs) with a cDNA encoding…”
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Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors by Hatano, Manabu, Kuwashima, Naruo, Tatsumi, Tomohide, Dusak, Jill E, Nishimura, Fumihiko, Reilly, Karlyne M, Storkus, Walter J, Okada, Hideho

“…BACKGROUND: A novel tyrosine kinase receptor EphA2 is expressed at high levels in advanced and metastatic cancers. We examined whether vaccinations with…”
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Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors by SASAKI, Kotaro, XINMEI ZHU, STORKUS, Walter J, OKADA, Hideho, VASQUEZ, Cecilia, NISHIMURA, Fumihiko, DUSAK, Jill E, JIAN HUANG, FUJITA, Mitsugu, WESA, Amy, POLLER, Douglas M, WALKER, Paul R

“…We have previously shown preferential tumor-homing and therapeutic efficacy of adoptively transferred type 1 CTL (Tc1) when compared with type 2 CTL (Tc2) in…”
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Identification of Interleukin-13 Receptor alpha 2 Peptide Analogues Capable of Inducing Improved Antiglioma CTL Responses by Eguchi, Junichi, Hatano, Manabu, Nishimura, Fumihiko, Zhu, Xinmei, Dusak, Jill E, Sato, Hidemitsu, Pollack, Ian F, Storkus, Walter J, Okada, Hideho

“…Restricted and high-level expression of interleukin-13 receptor alpha 2 (IL-13R alpha 2) in a majority of human malignant gliomas makes this protein an…”
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IL-4-Transfected Tumor Cell Vaccines Activate Tumor-Infiltrating Dendritic Cells and Promote Type-1 Immunity by Eguchi, Junichi, Kuwashima, Naruo, Hatano, Manabu, Nishimura, Fumihiko, Dusak, Jill E, Storkus, Walter J, Okada, Hideho

“…We previously demonstrated that IL-4 gene-transfected glioma cell vaccines induce effective therapeutic immunity in preclinical glioma models, and have…”
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Delivery of dendritic cells engineered to secrete IFN-alpha into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: dependence on apoptotic pathways by Kuwashima, Naruo, Nishimura, Fumihiko, Eguchi, Junichi, Sato, Hidemitsu, Hatano, Manabu, Tsugawa, Takahiko, Sakaida, Tsukasa, Dusak, Jill E, Fellows-Mayle, Wendy K, Papworth, Glenn D, Watkins, Simon C, Gambotto, Andrea, Pollack, Ian F, Storkus, Walter J, Okada, Hideho

“…We tested whether modulation of the CNS-tumor microenvironment by delivery of IFN-alpha-transduced dendritic cells (DCs: DC-IFN-alpha) would enhance the…”
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Delivery of interferon-α transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines by OKADA, Hideho, TSUGAWA, Takahiko, CHAMBERS, William H, POTTER, Douglas M, STORKUS, Walter J, POLLACK, Ian F, SATO, Hidemitsu, KUWASHIMA, Naruo, GAMBOTTO, Andrea, OKADA, Kaori, DUSAK, Jill E, FELLOWS-MAYLE, Wendy K, PAPWORTH, Glenn D, WATKINS, Simon C

“…We evaluated the effects, on immunity and survival, of injection of interferon (IFN)-alpha-transfected dendritic cells (DC-IFN-alpha) into intracranial tumors…”
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Identification of Interleukin-13 Receptor α2 Peptide Analogues Capable of Inducing Improved Antiglioma CTL Responses by Eguchi, Junichi, Hatano, Manabu, Nishimura, Fumihiko, Zhu, Xinmei, Dusak, Jill E., Sato, Hidemitsu, Pollack, Ian F., Storkus, Walter J., Okada, Hideho

“…Restricted and high-level expression of interleukin-13 receptor α2 (IL-13Rα2) in a majority of human malignant gliomas makes this protein an attractive vaccine…”
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Identification of interleukin-13 receptor alpha2 peptide analogues capable of inducing improved antiglioma CTL responses by Eguchi, Junichi, Hatano, Manabu, Nishimura, Fumihiko, Zhu, Xinmei, Dusak, Jill E, Sato, Hidemitsu, Pollack, Ian F, Storkus, Walter J, Okada, Hideho

“…Restricted and high-level expression of interleukin-13 receptor alpha2 (IL-13Ralpha2) in a majority of human malignant gliomas makes this protein an attractive…”
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Identification of lnterleukin-13 receptor α2 peptide analogues capable of inducing improved antiglioma CTL responses by EGUCHI, Junichi, HATANO, Manabu, NISHIMURA, Fumihiko, XINMEI ZHU, DUSAK, Jill E, SATO, Hidemitsu, POLLACK, Ian F, STORKUS, Walter J, OKADA, Hideho

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EphA2 as a Glioma-Associated Antigen: A Novel Target for Glioma Vaccines1 by Hatano, Manabu, Eguchi, Junichi, Tatsumi, Tomohide, Kuwashima, Naruo, Dusak, Jill E, Kinch, Michel S, Pollack, Ian F, Hamilton, Ronald L, Storkus, Walter J, Okada, Hideho

“…EphA2 is a receptor tyrosine kinase and is frequently overexpressed in a wide array of advanced cancers. We demonstrate in the current study that the EphA2…”
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Delivery of Dendritic Cells Engineered to Secrete IFN-{alpha} into Central Nervous System Tumors Enhances the Efficacy of Peripheral Tumor Cell Vaccines: Dependence on Apoptotic Pathways by Kuwashima, Naruo, Nishimura, Fumihiko, Eguchi, Junichi, Sato, Hidemitsu, Hatano, Manabu, Tsugawa, Takahiko, Sakaida, Tsukasa, Dusak, Jill E, Fellows-Mayle, Wendy K, Papworth, Glenn D, Watkins, Simon C, Gambotto, Andrea, Pollack, Ian F, Storkus, Walter J, Okada, Hideho

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