Search Results - "Dus̆inská, M."
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Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats
Published in Journal of applied toxicology (01-11-2012)“…ABSTRACT Silver nanoparticles (AgNPs) are the most commonly used nanoparticles owing to their antimicrobial properties. The motivation of the present study was…”
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Evaluating the climate and air quality impacts of short-lived pollutants
Published in Atmospheric chemistry and physics (24-09-2015)“…This paper presents a summary of the work done within the European Union's Seventh Framework Programme project ECLIPSE (Evaluating the Climate and Air Quality…”
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The comet assay in human biomonitoring: gene–environment interactions
Published in Mutagenesis (01-05-2008)“…The comet assay is the method of choice for measuring DNA damage, of various sorts, in human cells such as lymphocytes obtained in the course of…”
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In vitro evaluation of the genotoxicity of poly(anhydride) nanoparticles designed for oral drug delivery
Published in International journal of pharmaceutics (15-05-2017)“…[Display omitted] In the last years, the development of nanomaterials has significantly increased due to the immense variety of potential applications in…”
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The miniaturized enzyme-modified comet assay for genotoxicity testing of nanomaterials
Published in Frontiers in toxicology (12-10-2022)“…The comet assay is a widely applied method for investigating genotoxicity of chemicals including engineered nanomaterials (NMs). A big challenge in hazard…”
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Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation
Published in Nanotoxicology (02-01-2019)“…This paper presents a comprehensive review of European Union (EU) legislation addressing the safety of chemical substances, and possibilities within each piece…”
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Towards an alternative testing strategy for nanomaterials used in nanomedicine: Lessons from NanoTEST
Published in Nanotoxicology (01-05-2015)“…Abstract In spite of recent advances in describing the health outcomes of exposure to nanoparticles (NPs), it still remains unclear how exactly NPs interact…”
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Impact of interleukin 13 (IL13) genetic polymorphism Arg130Gln on total serum immunoglobulin (IgE) levels and interferon (IFN)‐γ gene expression
Published in Clinical and experimental immunology (01-04-2017)“…Summary This cross‐sectional study was designed to investigate the extent of genetic susceptibility by targeting variants in interleukin (IL)−4/IL‐13…”
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Impact of interleukin 13 (IL13) genetic polymorphism Arg130Gln on total serum immunoglobulin (IgE) levels and interferon (IFN)-[gamma] gene expression
Published in Clinical and experimental immunology (01-04-2017)“…Summary This cross-sectional study was designed to investigate the extent of genetic susceptibility by targeting variants in interleukin (IL)-4/IL-13…”
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Human health risk assessment of nitrosamines and nitramines for potential application in CO2 capture
Published in Regulatory toxicology and pharmacology (01-07-2014)“…•Nitrosamines and nitramines may be emitted as part of the CO2 capture process.•Many of these substances have genotoxic potential.•A risk characterization for…”
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Effects of diet and age on oxidative damage products in healthy subjects
Published in Physiological research (01-01-2008)“…Damage of molecules as a consequence of oxidative stress has been implicated in the pathogenesis of chronic diseases related to aging. Diet is a key…”
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DNA damage and antioxidants; fluctuations through the year in a central European population group
Published in Food and chemical toxicology (01-08-2002)“…Dietary antioxidant levels in the blood depend on intake of fruits and vegetables and therefore might be expected to show seasonal variation. A group of…”
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Oxidative Damage to DNA: Do We Have a Reliable Biomarker?
Published in Environmental health perspectives (01-05-1996)“…Oxidized bases in DNA can be measured directly by high-performance liquid chromatography (HPLC). 7,8-Dihydro-8-oxo-guanine (8-OHgua), as the most abundant…”
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Use of single cell gel electrophoresis assays for the detection of DNA-protective effects of dietary factors in humans: Recent results and trends
Published in Mutation research (01-01-2009)“…This article summarises the results of human dietary intervention trials employing the comet assay (single cell gel electrophoresis, SCGE), which have been…”
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Nutritional supplementation with antioxidants decreases chromosomal damage in humans
Published in Mutagenesis (01-07-2003)“…In order to investigate the effects of antioxidant supplementation on chromosome damage, a 3 month antioxidant supplementation trial was conducted on groups of…”
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Global and gene specific DNA methylation in breast cancer cells was not affected during epithelial-to-mesenchymal transition in vitro
Published in Neoplasma (2016)“…Epithelial-to-mesenchymal transition (EMT) significantly affects the risk of metastasising in breast cancer. Plasticity and reversibility of EMT suggest that…”
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Inter-individual differences in repair of DNA base oxidation, measured in vitro with the comet assay
Published in Mutagenesis (01-07-2001)“…There is a need for a reliable, robust and sensitive assay for DNA repair, suitable for use with human lymphocyte samples in molecular epidemiological…”
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Biological activity of plant extract isolated from Papaver rhoeas on human lymfoblastoid cell line
Published in Neoplasma (2011)“…Varied medicinal plants are known as a source of natural phytochemicals with antioxidant activities that can protect organisms from oxidative stress and from…”
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Comet assay in human biomonitoring studies: Reliability, validation, and applications
Published in Environmental and molecular mutagenesis (1997)“…The comet assay (single‐cell gel electrophoresis), which measures DNA strand breaks at the level of single cells, is very easily applied to human lymphocytes,…”
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