Search Results - "Duru, Nadire"

Fibrinolysis and Inflammation in Venous Thrombus Resolution by Mukhopadhyay, Subhradip, Johnson, Tierra A, Duru, Nadire, Buzza, Marguerite S, Pawar, Nisha R, Sarkar, Rajabrata, Antalis, Toni M

“…Clinical observations and accumulating laboratory evidence support a complex interplay between coagulation, inflammation, innate immunity and fibrinolysis in…”
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Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer by Gernapudi, Ramkishore, Yao, Yuan, Zhang, Yongshu, Wolfson, Benjamin, Roy, Sanchita, Duru, Nadire, Eades, Gabriel, Yang, Peixin, Zhou, Qun

“…The tumor microenvironment plays a critical role in regulating breast tumor progression. Signaling between preadipocytes and breast cancer cells has been found…”
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Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis by Lo, Pang-Kuo, Zhang, Yongshu, Wolfson, Benjamin, Gernapudi, Ramkishore, Yao, Yuan, Duru, Nadire, Zhou, Qun

“…Dysregulation of long non-codng RNA (lncRNA) expression has been found to contribute to tumorigenesis. However, the roles of lncRNAs in BRCA1-related breast…”
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HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells by DURU, Nadire, MING FAN, SHIYONG LI, SPITZ, Douglas R, LAM, Kit S, WICHA, Max S, JIAN JIAN LI, CANDAS, Demet, MENAA, Cheikh, LIU, Hsin-Chen, NANTAJIT, Danupon, YUNFEI WEN, KAI XIAO, ELDRIDGE, Angela, CHROMY, Brett A

“…To understand the role of HER2-associated signaling network in breast cancer stem cells (BCSC) using radioresistant breast cancer cells and clinical recurrent…”
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Three Dimensional Culture of Human Renal Cell Carcinoma Organoids by Batchelder, Cynthia A, Martinez, Michele L, Duru, Nadire, Meyers, Frederick J, Tarantal, Alice F

“…Renal cell carcinomas arise from the nephron but are heterogeneous in disease biology, clinical behavior, prognosis, and response to systemic therapy…”
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Cyclin B1/Cdk1 phosphorylation of mitochondrial p53 induces anti-apoptotic response by Nantajit, Danupon, Fan, Ming, Duru, Nadire, Wen, Yunfei, Reed, John C, Li, Jian Jian

“…The pro-apoptotic function of p53 has been well defined in preventing genomic instability and cell transformation. However, the intriguing fact that p53…”
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Characterization of the CD49f+/CD44+/CD24- single-cell derived stem cell population in basal-like DCIS cells by Duru, Nadire, Gernapudi, Ramkishore, Lo, Pang-Kuo, Yao, Yuan, Wolfson, Benjamin, Zhang, Yongshu, Zhou, Qun

“…The molecular mechanisms responsible for the Ductal Carcinoma in Situ (DCIS)-Invasive Ductal Carcinoma (IDC) transition have yet to be elucidated. Due to the…”
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Leptin-regulated gene expression in MCF-7 breast cancer cells: mechanistic insights into leptin-regulated mammary tumor growth and progression by Perera, Candida N, Chin, Hwei G, Duru, Nadire, Camarillo, Ignacio G

“…Obesity is a recently established risk factor for breast cancer incidence and mortality. A characteristic of obesity is elevated circulating levels of…”
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Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility by Snijders, Antoine M, Marchetti, Francesco, Bhatnagar, Sandhya, Duru, Nadire, Han, Ju, Hu, Zhi, Mao, Jian-Hua, Gray, Joe W, Wyrobek, Andrew J

“…High dose ionizing radiation (IR) is a well-known risk factor for breast cancer but the health effects after low-dose (LD, <10 cGy) exposures remain highly…”
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Mechanisms of the alternative activation of macrophages and non-coding RNAs in the development of radiation-induced lung fibrosis by Duru, Nadire, Wolfson, Benjamin, Zhou, Qun

“…Radiation-induced lung fibrosis(RILF) is a common side effect of thoracic irradiation therapy and leads to high mortality rates after cancer treatment…”
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YY1 is a novel potential therapeutic target for the treatment of HPV infection-induced cervical cancer by arsenic trioxide by He, Guifen, Wang, Qian, Zhou, Yuqi, Wu, Xiaohua, Wang, Lan, Duru, Nadire, Kong, Xiangtao, Zhang, Pingzhao, Wan, Bo, Sui, Long, Guo, Qisang, Li, Jian-Jian, Yu, Long

“…YY1 is a zinc finger transcription factor involved in the regulation of cell growth, development, and differentiation. Although YY1 can regulate human…”
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Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M Progression by Wang, Zhaoqing, Fan, Ming, Candas, Demet, Zhang, Tie-Qiao, Qin, Lili, Eldridge, Angela, Wachsmann-Hogiu, Sebastian, Ahmed, Kazi M., Chromy, Brett A., Nantajit, Danupon, Duru, Nadire, He, Fuchu, Chen, Min, Finkel, Toren, Weinstein, Lee S., Li, Jian Jian

“…A substantial amount of mitochondrial energy is required for cell-cycle progression. The mechanisms underlying the coordination of the mitochondrial…”
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Matriptase drives dissemination of ovarian cancer spheroids by a PAR-2/PI3K/Akt/MMP9 signaling axis by Pawar, Nisha R, Buzza, Marguerite S, Duru, Nadire, Strong, Amando A, Antalis, Toni M

“…The transmembrane serine protease matriptase is a key regulator of both barrier-disruptive and protective epithelial cell-cell interactions. Elevated…”
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Breast cancer adaptive resistance: HER2 and cancer stem cell repopulation in a heterogeneous tumor society by Duru, Nadire, Candas, Demet, Jiang, Guochun, Li, Jian Jian

“…Purpose The lethal effects of cancer are associated with the enhanced tumor aggressiveness in recurrent and metastatic lesions that show resistant phenotype to…”
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Tumor-associated myoepithelial cells promote the invasive progression of ductal carcinoma in situ through activation of TGFβ signaling by Lo, Pang-Kuo, Zhang, Yongshu, Yao, Yuan, Wolfson, Benjamin, Yu, Justine, Han, Shu-Yan, Duru, Nadire, Zhou, Qun

“…The normal myoepithelium has a tumor-suppressing nature and inhibits the progression of ductal carcinoma in situ (DCIS) into invasive ductal carcinoma (IDC)…”
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A High-Fat Diet Promotes Mammary Gland Myofibroblast Differentiation through MicroRNA 140 Downregulation by Wolfson, Benjamin, Zhang, Yongshu, Gernapudi, Ramkishore, Duru, Nadire, Yao, Yuan, Lo, Pang-Kuo, Zhou, Qun

“…Human breast adipose tissue is a heterogeneous cell population consisting of mature white adipocytes, multipotent mesenchymal stem cells, committed progenitor…”
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Noncoding RNAs in breast cancer by Lo, Pang-Kuo, Wolfson, Benjamin, Zhou, Xipeng, Duru, Nadire, Gernapudi, Ramkishore, Zhou, Qun

“…The mammalian transcriptome has recently been revealed to encompass a large number of noncoding RNAs (ncRNAs) that play a variety of important regulatory roles…”
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NRF2/miR-140 signaling confers radioprotection to human lung fibroblasts by Duru, Nadire, Gernapudi, Ramkishore, Zhang, Yongshu, Yao, Yuan, Lo, Pang-Kuo, Wolfson, Benjamin, Zhou, Qun

“…Highlights • Ionizing radiation induces BRCA1-dependent activation of NRF2 in human lung fibroblasts. • BRCA1 activates NRF2 through the negative regulation of…”
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Protease‐activated receptor 2 (PAR‐2) biased agonism in ovarian cancer progression by Pawar, Nisha R., Duru, Nadire, Conway, Gregory D., Antalis, Toni M.

“…Ovarian cancer is one of the most fatal gynecological malignancies due to its delayed clinical presentation, indicating a need to investigate molecular…”
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The role of Plasminogen Activator Inhibitor Type‐2 (PAI‐2) in modulating venous thrombus resolution by Johnson, Tierra A, Mukhopadhyay, Subhradip, Duru, Nadire, Buzza, Marguerite S, Antalis, Toni M

“…Deep Vein Thrombosis (DVT) which can arise from vascular endothelial injury, venous stasis, and/or alterations in blood hypercoagulability, affects patients of…”
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