Search Results - "Durston, Antony"
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What are the roles of retinoids, other morphogens, and Hox genes in setting up the vertebrate body axis?
Published in Genesis (New York, N.Y. : 2000) (01-07-2019)“…Summary This article is concerned with the roles of retinoids and other known anterior–posterior morphogens in setting up the embryonic vertebrate…”
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A Tribute to Lewis Wolpert and His Ideas on the 50th Anniversary of the Publication of His Paper 'Positional Information and the Spatial Pattern of Differentiation'. Evidence for a Timing Mechanism for Setting Up the Vertebrate Anterior-Posterior (A-P) Axis
Published in International journal of molecular sciences (07-04-2020)“…This article is a tribute to Lewis Wolpert and his ideas on the occasion of the recent 50th anniversary of the publication of his article 'Positional…”
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Collinear Hox-Hox interactions are involved in patterning the vertebrate anteroposterior (A-P) axis
Published in PloS one (11-04-2017)“…Investigating regulation and function of the Hox genes, key regulators of positional identity in the embryo, opened a new vista in developmental biology. One…”
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A tribute to D'Arcy Wentworth Thompson: Elucidation of a developmental principle
Published in BioEssays (01-08-2017)“…We show the vertebrate anterior –posterior axis is made by time space translation (TST). 1/ TST of Hox temporal to spatial collinearity makes the trunk part of…”
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Dislocation is a developmental mechanism in Dictyostelium and vertebrates
Published in Proceedings of the National Academy of Sciences - PNAS (03-12-2013)“…The excitable cells of Dictyostelium discoideum show traveling waves of signaling and generate a variety of complex wave forms during their morphogenesis…”
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Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning
Published in Frontiers in cell and developmental biology (29-11-2019)“…The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the…”
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Hoxc6 loss of function truncates the main body axis in Xenopus
Published in Cell cycle (Georgetown, Tex.) (03-06-2017)Get full text
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Patterning of the Vertebrate Head in Time and Space by BMP Signaling
Published in Journal of developmental biology (03-07-2023)“…How head patterning is regulated in vertebrates is yet to be understood. In this study, we show that frog embryos injected with Noggin at different blastula…”
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Two Tier Hox Collinearity Mediates Vertebrate Axial Patterning
Published in Frontiers in cell and developmental biology (04-09-2018)“…A two tier mechanism mediates Hox collinearity. Besides the familiar collinear chromatin modification within each Hox cluster (nanocollinearity), there is also…”
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Spiral waves and vertebrate embryonic handedness
Published in Journal of biosciences (01-06-2018)“…During early embryonic development, the vertebrate main body axis is segmented from head-to-tail into somites. Somites emerge sequentially from the presomitic…”
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Axial patterning in snakes and caecilians: Evidence for an alternative interpretation of the Hox code
Published in Developmental biology (01-08-2009)“…It is generally assumed that the characteristic deregionalized body plan of species with a snake-like morphology evolved through a corresponding homogenization…”
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MiR-10 represses HoxB1a and HoxB3a in zebrafish
Published in PloS one (02-01-2008)“…The Hox genes are involved in patterning the anterior-posterior axis. In addition to the protein coding Hox genes, the miR-10, miR-196 and miR-615 families of…”
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Vertical signalling involves transmission of Hox information from gastrula mesoderm to neurectoderm
Published in PloS one (16-12-2014)“…Development and patterning of neural tissue in the vertebrate embryo involves a set of molecules and processes whose relationships are not fully understood…”
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The zebrafish hoxDb cluster has been reduced to a single microRNA
Published in Nature genetics (01-06-2006)“…The zebrafish hoxDb cluster has been reduced to a single microRNA. The animal hox clusters consist of clustered homeodomain transcription factors involved in…”
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Extensive polycistronism and antisense transcription in the mammalian Hox clusters
Published in PloS one (04-04-2007)“…The Hox clusters play a crucial role in body patterning during animal development. They encode both Hox transcription factor and micro-RNA genes that are…”
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XMeis3 is necessary for mesodermal Hox gene expression and function
Published in PloS one (28-03-2011)“…Hox transcription factors provide positional information during patterning of the anteroposterior axis. Hox transcription factors can co-operatively bind with…”
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Xwnt8 directly initiates expression of labial Hox genes
Published in Developmental dynamics (01-01-2010)“…Hox transcription factors play an essential role in patterning the anteroposterior axis during embryogenesis and exhibit a complex array of spatial and…”
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Knockdown of the complete Hox paralogous group 1 leads to dramatic hindbrain and neural crest defects
Published in Development (Cambridge) (01-06-2005)“…The Hox paralogous group 1 (PG1) genes are the first and initially most anterior Hox genes expressed in the embryo. In Xenopus , the three PG1 genes, Hoxa1 ,…”
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Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution
Published in Journal of comparative neurology (1911) (10-01-2008)“…Knockout of the Nkx2.1 (Titf‐1) homeobox gene in the mouse leads to severe malformation and size reduction of the basal telencephalon/preoptic area and basal…”
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Hox collinearity - a new perspective
Published in The International journal of developmental biology (2011)“…Hox collinearity is a spectacular phenomenon that has excited life scientists since its discovery in 1978. Two mechanisms have been proposed to explain the…”
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