Search Results - "Durocher, Francine"

The Importance of Breast Adipose Tissue in Breast Cancer by Kothari, Charu, Diorio, Caroline, Durocher, Francine

“…Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose tissue is generally linked to excessive body fat, and it is well known…”
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Breast Cancer and Microcalcifications: An Osteoimmunological Disorder? by Clemenceau, Alisson, Michou, Laetitia, Diorio, Caroline, Durocher, Francine

“…The presence of microcalcifications in the breast microenvironment, combined with the growing evidences of the possible presence of osteoblast-like or…”
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Adiposity, breast density, and breast cancer risk: epidemiological and biological considerations by Soguel, Ludivine, Durocher, Francine, Tchernof, André, Diorio, Caroline

“…Excess total body fat and abdominal adipose tissue are recognized risk factors for metabolic diseases but also for some types of cancers, including breast…”
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Epigenome-wide DNA methylation and risk of breast cancer: a systematic review by Ennour-Idrissi, Kaoutar, Dragic, Dzevka, Durocher, Francine, Diorio, Caroline

“…DNA methylation is a potential biomarker for early detection of breast cancer. However, robust evidence of a prospective relationship between DNA methylation…”
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Trastuzumab effects depend on HER2 phosphorylation in HER2-negative breast cancer cell lines by Burguin, Anna, Furrer, Daniela, Ouellette, Geneviève, Jacob, Simon, Diorio, Caroline, Durocher, Francine

“…The breast cancer (BC) biomarker HER2 (Human Epidermal Receptor 2) is overexpressed in 25% of BC. Only patients with HER2-positive tumors receive…”
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The emergence of an ethical duty to disclose genetic research results: international perspectives by KNOPPERS, Bartha Maria, JOLY, Yann, SIMARD, Jacques, DUROCHER, Francine

“…The last decade has witnessed the emergence of international ethics guidelines discussing the importance of disclosing global and also, in certain…”
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Machine learning analysis identifies genes differentiating triple negative breast cancers by Kothari, Charu, Osseni, Mazid Abiodoun, Agbo, Lynda, Ouellette, Geneviève, Déraspe, Maxime, Laviolette, François, Corbeil, Jacques, Lambert, Jean-Philippe, Diorio, Caroline, Durocher, Francine

“…Triple negative breast cancer (TNBC) is one of the most aggressive form of breast cancer (BC) with the highest mortality due to high rate of relapse,…”
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Exploring the impact of night shift work on methylation of circadian genes by Ritonja, Jennifer A., Aronson, Kristan J., Flaten, Lisa, Topouza, Danai G., Duan, Qing Ling, Durocher, Francine, Tranmer, Joan E., Bhatti, Parveen

“…Night shift work is associated with increased breast cancer risk, but the molecular mechanisms are not well-understood. The objective of this study was to…”
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Role of Secreted Frizzled-Related Protein 1 in Early Mammary Gland Tumorigenesis and Its Regulation in Breast Microenvironment by Clemenceau, Alisson, Diorio, Caroline, Durocher, Francine

“…In mice, the lack of ( ) is responsible for mammogenesis and hyperplasia, while, in bovines, its overexpression is associated with post-lactational mammary…”
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Associations of Biomarkers of Inflammation and Breast Cancer in the Breast Adipose Tissue of Women with Combined Measures of Adiposity by Chang, Sue-Ling, Tchernof, André, Durocher, Francine, Diorio, Caroline

“…Background. Mechanisms underlying the obesity-breast cancer link involve inflammation but need to be elucidated. Determining obesity by combining body mass…”
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An isoform of AIF1 involved in breast cancer by Slim, Ferial Amira, Ouellette, Geneviève, Ennour-Idrissi, Kaoutar, Jacob, Simon, Diorio, Caroline, Durocher, Francine

“…Inflammation is a major player in breast cancer (BC) progression. Allograft-inflammatory factor-1 (AIF1) is a crucial mediator in the inflammatory response…”
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Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population by Litim, Nadhir, Labrie, Yvan, Desjardins, Sylvie, Ouellette, Geneviève, Plourde, Karine, Belleau, Pascal, Durocher, Francine

“…The majority of genes associated with breast cancer susceptibility, including BRCA1 and BRCA2 genes, are involved in DNA repair mechanisms. Moreover, among the…”
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Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families by Plourde, Karine V, Labrie, Yvan, Desjardins, Sylvie, Belleau, Pascal, Ouellette, Geneviève, Durocher, Francine

“…ZNF350/ZBRK1 is a transcription factor, which associates with BRCA1 to co-repress GADD45A to regulate DNA damage repair, and the expression of ZNF350 is…”
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Breast Cancer Treatments: Updates and New Challenges by Burguin, Anna, Diorio, Caroline, Durocher, Francine

“…Breast cancer (BC) is the most frequent cancer diagnosed in women worldwide. This heterogeneous disease can be classified into four molecular subtypes (luminal…”
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Variations in the NBN/NBS1 gene and the risk of breast cancer in non-BRCA1/2 French Canadian families with high risk of breast cancer by Desjardins, Sylvie, Beauparlant, Joly Charles, Labrie, Yvan, Ouellette, Geneviève, Durocher, Francine

“…The Nijmegen Breakage Syndrome is a chromosomal instability disorder characterized by microcephaly, growth retardation, immunodeficiency, and increased…”
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Genetic sequence variations of BRCA1-interacting genes AURKA, BAP1, BARD1 and DHX9 in French Canadian families with high risk of breast cancer by Guénard, Frédéric, Labrie, Yvan, Ouellette, Geneviève, Beauparlant, Charles Joly, Durocher, Francine

“…Breast cancer is a heterogeneous disease displaying some degree of familial clustering. Highly penetrant breast cancer susceptibility genes represent…”
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Mutation analysis and characterization of ATR sequence variants in breast cancer cases from high-risk French Canadian breast/ovarian cancer families by Durocher, Francine, Labrie, Yvan, Soucy, Penny, Sinilnikova, Olga, Labuda, Damian, Bessette, Paul, Chiquette, Jocelyne, Laframboise, Rachel, Lépine, Jean, Lespérance, Bernard, Ouellette, Geneviève, Pichette, Roxane, Plante, Marie, Tavtigian, Sean V, Simard, Jacques

“…Ataxia telangiectasia-mutated and Rad3-related (ATR) is a member of the PIK-related family which plays, along with ATM, a central role in cell-cycle…”
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AURKA F31I Polymorphism and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers: A Consortium of Investigators of Modifiers of BRCA1/2 Study by COUCH, Fergus J, SINILNIKOVA, Olga, PEOCK, Susan, COOK, Margaret, BAYNES, Caroline, HODGSON, Shirley, MORRISON, Patrick J, PORTEOUS, Mary E, JAKUBOWSKA, Anna, LUBINSKI, Jan, GRONWALD, Jacek, SPURDLE, Amanda B, VIERKANT, Robert A, KCONFAB, SCHMUTZLER, Rita, VERSMOLD, Beatrix, ENGEL, Christoph, MEINDL, Alfons, SUTTER, Christian, HORST, Jurgen, SCHAEFER, Dieter, OFFIT, Kenneth, KIRCHHOFF, Tomas, PANKRATZ, V. Shane, ANDRULIS, Irene L, ILYUSHIK, Eduard, GLENDON, Gordon, DEVILEE, Peter, VREESWIJK, Maaike P. G, VASEN, Hans F. A, BORG, Ake, BACKENHORN, Katja, STRUEWING, Jeffery P, GREENE, Mark H, FREDERICKSEN, Zachary S, NEUHAUSEN, Susan L, REBBECK, Timothy R, NATHANSON, Katherine, DOMCHEK, Susan, WAGNER, Theresa, GARBER, Judy E, SZABO, Csilla, ZIKAN, Michal, FORETOVA, Lenka, OLSON, Janet E, STOPPA-LYONNET, Dominique, SELLERS, Thomas A, LINDOR, Noralane, NEVANLINNA, Heli, TOMMISKA, Johanna, AITTOMAKI, Kristiina, HAMANN, Ute, RASHID, Muhammad U, TORRES, Diana, SIMARD, Jacques, DUROCHER, Francine, COUPIER, Isabelle, HUGHES, David, HARDOUIN, Agnès, BERTHET, Pascaline

“…The AURKA oncogene is associated with abnormal chromosome segregation and aneuploidy and predisposition to cancer. Amplification of AURKA has been detected at…”
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Sleep quality traits correlate with inflammatory markers in the breast tissue of women by Chang, Sue-Ling, Durocher, Francine, Diorio, Caroline

“…[Display omitted] •Inflammation may be involved in the sleep and breast cancer association.•Tissue-based inflammatory markers examined with sleep duration,…”
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Mutation analysis and characterization of HSD17B2 sequence variants in breast cancer cases from French Canadian families with high risk of breast and ovarian cancer by Plourde, Marie, Manhes, Caroline, Leblanc, Gilles, Durocher, Francine, Dumont, Martine, Sinilnikova, Olga, BRCAs, INHERIT, Simard, Jacques

“…Estrogen exposure is a risk factor for breast cancer. Given that HSD17B2 gene encodes an enzyme that catalyses estradiol inactivation, it appears as a good…”
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