Search Results - "Durif, G."
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1
Kernel-based testing for single-cell differential analysis
Published in Genome Biology (03-05-2024)“…Single-cell technologies offer insights into molecular feature distributions, but comparing them poses challenges. We propose a kernel-testing framework for…”
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Noninvasive prenatal diagnosis of genetic diseases induced by triplet repeat expansion by linked read haplotyping and Bayesian approach
Published in Scientific reports (06-07-2022)“…The field of noninvasive prenatal diagnosis (NIPD) has undergone significant progress over the last decade. Direct haplotyping has been successfully applied…”
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The Fate of a Polygenic Phenotype Within the Genomic Landscapes of Introgression in the European Seabass Hybrid Zone
Published in Molecular biology and evolution (04-09-2024)“…Abstract Unraveling the evolutionary mechanisms and consequences of hybridization is a major concern in biology. Many studies have documented the interplay…”
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4
Probabilistic count matrix factorization for single cell expression data analysis
Published in Bioinformatics (15-10-2019)“…Abstract Motivation The development of high-throughput single-cell sequencing technologies now allows the investigation of the population diversity of cellular…”
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High dimensional classification with combined adaptive sparse PLS and logistic regression
Published in Bioinformatics (01-02-2018)“…Abstract Motivation The high dimensionality of genomic data calls for the development of specific classification methodologies, especially to prevent…”
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DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification
Published in BMC bioinformatics (02-10-2021)“…Abstract Background Quantification of tumor heterogeneity is essential to better understand cancer progression and to adapt therapeutic treatments to patient…”
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Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans
Published in Cell reports (Cambridge) (25-05-2021)“…The CD8+ T cell response to an antigen is composed of many T cell clones with unique T cell receptors, together forming a heterogeneous repertoire of effector…”
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High Dimensional Classification with combined Adaptive Sparse PLS and Logistic Regression
Published 30-08-2017“…Bioinformatics 34, 485-493 (2018) Motivation: The high dimensionality of genomic data calls for the development of specific classification methodologies,…”
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