Search Results - "Durham, Dianne"

Canalostomy as a Surgical Approach for Cochlear Gene Therapy in the Rat by Gassner, Davina, Durham, Dianne, Pfannenstiel, Susanna C., Brough, Douglas E., Staecker, Hinrich

“…This article presents a unique approach for the delivery of gene therapy vectors into the cochlea of the laboratory rat. Mice and guinea pigs are established…”
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Women Physicians and Promotion in Academic Medicine by Richter, Kimber P, Clark, Lauren, Wick, Jo A, Cruvinel, Erica, Durham, Dianne, Shaw, Pamela, Shih, Grace H, Befort, Christie A, Simari, Robert D

“…In analyses of data on graduates from all U.S. medical schools from 1979 through 2013, women were less likely than men to be promoted from assistant to…”
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Conductive Hearing Loss Results in a Decrease in Central Auditory System Activity in the Young Gerbil by Tucci, Debara L., Cant, Nell B., Durham, Dianne

“…Objectives/Hypothesis: The impact of childhood conductive HL (CHL) on development of auditory function has long been debated. The present study was conducted…”
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Early Onset Region and Cell Specific Alterations of Doublecortin Expression in the CNS of Animals with Sound Damage Induced Hearing Loss by Freemyer, Andrea, Neal, Christopher, Nelson-Brantley, Jennifer, Staecker, Hinrich, Durham, Dianne

“…•Unilateral sound damage was used, survival time 25-30 days post damage•Significant hearing loss at 5/7 tested frequencies•Hearing loss related increases in…”
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Post-tenure Review at U.S. Medical Schools by Bunton, Sarah A., Walling, Anne, Durham, Dianne

“…PURPOSETo assess post-tenure review policies at U.S. medical schools by examining how prevalent post-tenure review is, what models of post-tenure review are…”
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Round window administration of gentamicin: a new method for the study of ototoxicity of cochlear hair cells by Husmann, Kathrin R, Morgan, Adam S, Girod, Douglas A, Durham, Dianne

“…Damage to inner ear sensory hair cells after systemic administration of ototoxic drugs has been documented in humans and animals. Birds have the ability to…”
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Methionine Sulfoxide Reductase A Knockout Mice Show Progressive Hearing Loss and Sensitivity to Acoustic Trauma by Alqudah, Safa, Chertoff, Mark, Durham, Dianne, Moskovitz, Jackob, Staecker, Hinrich, Peppi, Marcello

“…Methionine sulfoxide reductases (MsrA and MsrB) protect the biological activity of proteins from oxidative modifications to methionine residues and are…”
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Hair cell counts in a rat model of sound damage: Effects of tissue preparation & identification of regions of hair cell loss by Neal, Christopher, Kennon-McGill, Stefanie, Freemyer, Andrea, Shum, Axel, Staecker, Hinrich, Durham, Dianne

“…Exposure to intense sound can damage or kill cochlear hair cells (HC). This loss of input typically manifests as noise induced hearing loss, but it can also be…”
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Afferent influences on brainstem auditory nuclei of the chick: nucleus magnocellularis neuronal activity following cochlea removal by Born, D E, Durham, D, Rubel, E W

“…Elimination of presynaptic elements often results in marked changes, such as atrophy and death, in postsynaptic neurons in the central nervous system. These…”
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Effects of neonatal whisker lesions on mouse central trigeminal pathways by Durham, D, Woolsey, T A

“…The mystacial vibrissae or whiskers on the face have a large representation in the rodent central nervous system. In rats and mice the projections arising from…”
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Hair Cell Counts in a Rat Model of Sound Damage: Effects of Tissue 1 Preparation & Identification of Regions of Hair Cell Loss by Neal, Christopher, Kennon-McGill, Stefanie, Freemyer, Andrea, Shum, Axel, Staecker, Hinrich, Durham, Dianne

“…Exposure to intense sound can damage or kill cochlear hair cells. This loss of input typically manifests as noise induced hearing loss, but it can also be…”
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Hearing, reactive metabolite formation, and oxidative stress in cochleae after a single acute overdose of acetaminophen: an in vivo study by McGill, Mitchell R., Kennon-McGill, Stefanie, Durham, Dianne, Jaeschke, Hartmut

“…Context: Although the liver is the primary target organ in acetaminophen (APAP) toxicity, other organs are affected. Previous data suggested that chronic APAP…”
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Efficacy and toxicity of peritumoral delivery of nanoconjugated cisplatin in an in vivo murine model of head and neck squamous cell carcinoma by Cohen, Stephanie M, Rockefeller, Nick, Mukerji, Ridhwi, Durham, Dianne, Forrest, M Laird, Cai, Shuang, Cohen, Mark S, Shnayder, Yelizaveta

“…Treatment of locally advanced head and neck squamous cell carcinoma (HNSCC) uses a multidisciplinary approach often limited by the toxicity and drug resistance…”
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Effect of unilateral noise exposure on the tonotopic distribution of spontaneous activity in the cochlear nucleus and inferior colliculus in the cortically intact and decorticate rat by Imig, Thomas J., Durham, Dianne

“…Effects of unilateral noise exposure on spontaneous activity (SA) in the anteroventral and dorsal cochlear nuclei (AVCN and DCN) and the central nucleus of the…”
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Histochemical and fluorescent analyses of mitochondrial integrity in chick auditory neurons following deafferentation by Karnes, Hope Elizabeth, Scaletty, Peter Nicholas, Durham, Dianne

“…Neurons rely exclusively on mitochondrial oxidative phosphorylation to meet cellular energy demands, and disruption of mitochondrial function often…”
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Functional organization in cortical barrels of normal and vibrissae-damaged mice: a (3H) 2-deoxyglucose study by Durham, D, Woolsey, T A

“…The large mystacial vibrissae on the faces of rodents have punctate representations in all stations in the central trigeminal pathway, including layer IV of…”
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Teaching of Anatomy in an Integrated, Electronic Curriculum: Implementation and Evaluation by Klein, Robert M, Durham, Dianne, Fishback, James L, Paolo, Anthony, Bonaminio, Giulia A, Shaw, Pam, Karr, Michael, Enders, George C

“…In 2006, KUSOM instituted a technology‐ and module‐based, integrated medical curriculum. Tablet PCs are used to integrate technology components and learning…”
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Effects of cochlea removal on GABAergic terminals in nucleus magnocellularis of the chicken by Code, R A, Durham, D, Rubel, E W

“…The effects of unilateral cochlea removal on GABA-immunoreactive (GABA-I) terminals in nucleus magnocellularis (NM) of the chick were assessed by…”
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Acute whisker removal reduces neuronal activity in barrels of mouse SmL cortex by Durham, D, Woolsey, T A

“…The autoradiographic 2-deoxy-D glucose (2-DG) method has been used to map relative changes in metabolic activity in the CNS during various functional states…”
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Afferent regulation of neurons in the brain stem auditory system by Rubel, E W, Hyson, R L, Durham, D

“…We have reviewed a series of experiments which begin to examine the cellular events underlying afferent regulation of neuronal structure. Our initial interest…”
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