Search Results - "Durett, April G"

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy by Di Stasi, Antonio, Tey, Siok-Keen, Dotti, Gianpietro, Fujita, Yuriko, Kennedy-Nasser, Alana, Martinez, Caridad, Straathof, Karin, Liu, Enli, Liu, Hao, Durett, April G, Grilley, Bambi, Cruz, Conrad R, Savoldo, Barbara, Gee, Adrian P, Schindler, John, Krance, Robert A, Heslop, Helen E, Spencer, David M, Rooney, Cliona M, Brenner, Malcolm K

“…The introduction of a transgene into human donor T cells that can kill the cells when dimerization is induced by a pharmacologic agent has improved prospects…”
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Manufacturing mesenchymal stromal cells for phase I clinical trials by Hanley, Patrick J, Mei, Zhuyong, da Graca Cabreira-Hansen, Maria, Klis, Mariola, Li, Wei, Zhao, Yali, Durett, April G, Zheng, Xingwu, Wang, Yongping, Gee, Adrian P, Horwitz, Edwin M

“…Abstract Mesenchymal stromal cells (MSCs) are multipotent progenitor cells capable of differentiating into adipocytes, osteoblasts and chondroblasts as well as…”
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Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation by Zhou, Xiaoou, Dotti, Gianpietro, Krance, Robert A., Martinez, Caridad A., Naik, Swati, Kamble, Rammurti T., Durett, April G., Dakhova, Olga, Savoldo, Barbara, Di Stasi, Antonio, Spencer, David M., Lin, Yu-Feng, Liu, Hao, Grilley, Bambi J., Gee, Adrian P., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K.

“…To test the feasibility of a single T-cell manipulation to eliminate alloreactivity while sparing antiviral and antitumor T cells, we infused 12 haploidentical…”
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Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene by Zhou, Xiaoou, Di Stasi, Antonio, Tey, Siok-Keen, Krance, Robert A., Martinez, Caridad, Leung, Kathryn S., Durett, April G., Wu, Meng-Fen, Liu, Hao, Leen, Ann M., Savoldo, Barbara, Lin, Yu-Feng, Grilley, Bambi J., Gee, Adrian P., Spencer, David M., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K., Dotti, Gianpietro

“…Adoptive transfer of donor-derived T lymphocytes expressing a safety switch may promote immune reconstitution in patients undergoing haploidentical…”
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Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications by Lapteva, Natalia, Durett, April G, Sun, Jiali, Rollins, Lisa A, Huye, Leslie L, Fang, Jian, Dandekar, Varada, Mei, Zhuyong, Jackson, Kimberley, Vera, Juan, Ando, Jun, Ngo, Minhtran C, Coustan-Smith, Elaine, Campana, Dario, Szmania, Susann, Garg, Tarun, Moreno-Bost, Amberly, Vanrhee, Frits, Gee, Adrian P, Rooney, Cliona M

“…Abstract Background aims Interest in natural killer (NK) cell-based immunotherapy has resurged since new protocols for the purification and expansion of large…”
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Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the Quantum Cell Expansion System by Hanley, Patrick J, Mei, Zhuyong, Durett, April G, da Graca Cabreira-Harrison, Marie, Klis, Mariola, Li, Wei, Zhao, Yali, Yang, Bing, Parsha, Kaushik, Mir, Osman, Vahidy, Farhaan, Bloom, Debra, Rice, R. Brent, Hematti, Peiman, Savitz, Sean I, Gee, Adrian P

“…Abstract Background The use of bone marrow–derived mesenchymal stromal cells (MSCs) as a cellular therapy for various diseases, such as graft-versus-host…”
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Jeane Hester, MD – Supervisor, Mentor, Collaborator and Friend by Durett, April G

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Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Therapy (PACT) translational application by Sun, Jiali, Huye, Leslie E, Lapteva, Natalia, Mamonkin, Maksim, Hiregange, Manasa, Ballard, Brandon, Dakhova, Olga, Raghavan, Darshana, Durett, April G, Perna, Serena K, Omer, Bilal, Rollins, Lisa A, Leen, Ann M, Vera, Juan F, Dotti, Gianpietro, Gee, Adrian P, Brenner, Malcolm K, Myers, Douglas G, Rooney, Cliona M

“…Virus-specific T-cells (VSTs) proliferate exponentially after adoptive transfer into hematopoietic stem cell transplant (HSCT) recipients, eliminate virus…”
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The Effect of the Composition of Unrelated Donor Bone Marrow and Peripheral Blood Progenitor Cell Grafts on Transplantation Outcomes by Collins, Nancy H, Gee, Adrian P, Durett, April G, Kan, Fangyu, Zhang, Mei-Jie, Champlin, Richard E, Confer, Dennis, Eapen, Mary, Howard, Alan, King, Roberta, Laughlin, Mary J, Plante, Robert J, Setterholm, Michelle, Spellman, Stephen, Keever-Taylor, Carolyn, Wagner, John E, Weisdorf, Daniel J

“…To test the hypothesis that the outcome of hematopoietic stem cell (HSC) grafts is at least partially determined by the cellular composition of the graft, the…”
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Generation of EBV-Specific CD4+ Cytotoxic T Cells from Virus Naive Individuals by Savoldo, Barbara, Cubbage, Michael L, Durett, April G, Goss, John, Huls, M. Helen, Liu, Zhensheng, Teresita, Lopez, Gee, Adrian P, Ling, Paul D, Brenner, Malcolm K, Heslop, Helen E, Rooney, Cliona M

“…Adoptive immunotherapy with EBV-specific CTL (EBV-CTL) effectively prevents and treats EBV-driven lymphoproliferation in immunocompromised hosts…”
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T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells by Lapteva, Natalia, Gilbert, Margaret, Diaconu, Iulia, Rollins, Lisa A, Al-Sabbagh, Mina, Naik, Swati, Krance, Robert A, Tripic, Tamara, Hiregange, Manasa, Raghavan, Darshana, Dakhova, Olga, Rouce, Rayne H, Liu, Hao, Omer, Bilal, Savoldo, Barbara, Dotti, Gianpietro, Cruz, Conrad Russel, Sharpe, Keli, Gates, Melissa, Orozco, Aaron, Durett, April, Pacheco, Elizabeth, Gee, Adrian P, Ramos, Carlos A, Heslop, Helen E, Brenner, Malcolm K, Rooney, Cliona M

“…Current protocols for CD19 chimeric antigen receptor-expressing T cells (CD19.CAR-T cells) require recipients to tolerate preinfusion cytoreductive…”
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Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells) by Perin, Emerson C, Murphy, Michael P, March, Keith L, Bolli, Roberto, Loughran, John, Yang, Phillip C, Leeper, Nicholas J, Dalman, Ronald L, Alexander, Jason, Henry, Timothy D, Traverse, Jay H, Pepine, Carl J, Anderson, R David, Berceli, Scott, Willerson, James T, Muthupillai, Raja, Gahremanpour, Amir, Raveendran, Ganesh, Velasquez, Omaida, Hare, Joshua M, Hernandez Schulman, Ivonne, Kasi, Vijaykumar S, Hiatt, William R, Ambale-Venkatesh, Bharath, Lima, João A, Taylor, Doris A, Resende, Micheline, Gee, Adrian P, Durett, April G, Bloom, Jeanette, Richman, Sara, G'Sell, Patricia, Williams, Shari, Khan, Fouzia, Gyang Ross, Elsie, Santoso, Michelle R, Goldman, JoAnne, Leach, Dana, Handberg, Eileen, Cheong, Benjamin, Piece, Nichole, DiFede, Darcy, Bruhn-Ding, Barb, Caldwell, Emily, Bettencourt, Judy, Lai, Dejian, Piller, Linda, Simpson, Lara, Cohen, Michelle, Sayre, Shelly L, Vojvodic, Rachel W, Moyé, Lem, Ebert, Ray F, Simari, Robert D, Hirsch, Alan T

“…Atherosclerotic peripheral artery disease affects 8% to 12% of Americans >65 years of age and is associated with a major decline in functional status,…”
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Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN Patients with Intermittent Claudication Injected with ALDH Bright Cells (PACE) Trial by Perin, Emerson C, Murphy, Michael P, March, Keith L, Bolli, Roberto, Loughran, John, Yang, Phillip C, Leeper, Nicholas J, Dalman, Ronald L, Alexander, Jason, Henry, Timothy D, Traverse, Jay H, Pepine, Carl J, Anderson, R David, Berceli, Scott, Willerson, James T, Muthupillai, Raja, Gahremanpour, Amir, Raveendran, Ganesh, Velasquez, Omaida, Hare, Joshua M, Schulman, Ivonne Hernandez, Kasi, Vijaykumar S, Hiatt, William R, Ambale-Venkatesh, Bharath, Lima, João A, Taylor, Doris A, Resende, Micheline, Gee, Adrian P, Durett, April G, Bloom, Jeanette, Richman, Sara, GʼSell, Patricia, Williams, Shari, Khan, Fouzia, Ross, Elsie Gyang, Santoso, Michelle R, Goldman, JoAnne, Leach, Dana, Handberg, Eileen, Cheong, Benjamin, Piece, Nichole, DiFede, Darcy, Bruhn-Ding, Barb, Caldwell, Emily, Bettencourt, Judy, Lai, Dejian, Piller, Linda, Simpson, Lara, Cohen, Michelle, Sayre, Shelly L, Vojvodic, Rachel W, Moyé, Lem, Ebert, Ray F, Simari, Robert D, Hirsch, Alan T

“…BACKGROUND—Atherosclerotic peripheral artery disease (PAD) affects 8-12% of Americans over 65 and is associated with a major decline in functional status,…”
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C-10. Inducible Caspase-9 Suicide Gene Controls Adverse Effects from Alloreplete T Cells after Haploidentical Stem Cell Transplantation by Zhou, Xiaoou, Dotti, Gianpietro, Krance, Robert A., Martinez, Caridad, Kamble, Rammurti T., Naik, Swati, Durett, April G., Dakhova, Olga, Savoldo, Barbara, Di Stasi, Antonio, Spencer, David M., Lin, Yu-Feng, Liu, Hao, Grilley, Bambi J., Gee, Adrian P., Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K.

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Efficient Manufacturing of Therapeutic Mesenchymal Stromal Cells Using the Quantum Cell Expansion System by Hanley, Patrick J., Mei, Zhuyong, Durett, April G., Cabreira-Harrison, Marie da Graca, Klis, Mariola, Li, Wei, Zhao, Yali, Yang, Bing, Parsha, Kaushik, Mir, Osman, Vahidy, Farhaan, Bloom, Debra, Rice, R. Brent, Hematti, Peiman, Savitz, Sean I, Gee, Adrian P.

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Flow Cytometric Analysis of Specimens by a Central Reference Laboratory in a Multi-Center Study: Factors Affecting Data Quality by Durett, April G., Gee, Adrian P., Collins, Nancy H., Eapen, Mary, Weisdorf, Daniel

“…Central reference flow cytometry laboratories are used in multicenter trials to eliminate inter laboratory variation in testing. Yet, factors that materially…”
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Identification of megakaryocyte precursors in peripheral blood stem cell collections from normal donors by Bojko, Peter, Hester, Jeane P., Durett, April G., Maadani, Farzaneh, Körbling, Martin, Champlin, Richard E.

“…Platelet engraftment, the time course and magnitude of platelet recovery (PR) post‐transplant, is imprecisely defined but is most often reported as the time to…”
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