Search Results - "Duret, Helene"

Pivotal Role of Innate and Adaptive Immunity in Anthracycline Chemotherapy of Established Tumors by MATTAROLLO, Stephen R, LOI, Sherene, DURET, Helene, MA, Yuting, ZITVOGEL, Laurence, SMYTH, Mark J

“…We show, in a series of established experimental breast adenocarcinomas and fibrosarcomas induced by carcinogen de novo in mice, that the therapeutic efficacy…”
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Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy by Stagg, John, Loi, Sherene, Divisekera, Upulie, Ngiow, Shin Foong, Duret, Helene, Yagita, Hideo, Teng, Michele W, Smyth, Mark J

“…Trastuzumab, a monoclonal antibody targeting human epidermal growth factor receptor-2 (HER2/ErbB-2), has become the mainstay of treatment for HER2-positive…”
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CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis by STAGG, John, DIVISEKERA, Upulie, DURET, Helene, SPARWASSER, Tim, TENG, Michele W. L, DARCY, Phillip K, SMYTH, Mark J

“…CD73 is a cell-surface enzyme that suppresses immune responses by producing extracellular adenosine. In this study, we employed CD73 gene-targeted mice to…”
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NLRP3 Suppresses NK Cell―Mediated Responses to Carcinogen-Induced Tumors and Metastases by CHOW, Melvyn T, SCENEAY, Jaclyn, PAGET, Christophe, WONG, Christina S. F, DURET, Helene, TSCHOPP, Jurg, MÖLLER, Andreas, SMYTH, Mark J

“…The NLRP3 inflammasome acts as a danger signal sensor that triggers and coordinates the inflammatory response upon infectious insults or tissue injury and…”
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Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State by TENG, Michele W. L, VESELY, Matthew D, DURET, Helene, MCLAUGHLIN, Nicole, TOWNE, Jennifer E, SCHREIBER, Robert D, SMYTH, Mark J

“…Cancer immunoediting, the process by which the immune system controls tumor growth and shapes tumor immunogenicity, consists of 3 stages: elimination,…”
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TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells by Biroccio, Annamaria, Cherfils-Vicini, Julien, Augereau, Adeline, Pinte, Sébastien, Bauwens, Serge, Ye, Jing, Simonet, Thomas, Horard, Béatrice, Jamet, Karine, Cervera, Ludovic, Mendez-Bermudez, Aaron, Poncet, Delphine, Grataroli, Renée, de Rodenbeeke, Claire T’kint, Salvati, Erica, Rizzo, Angela, Zizza, Pasquale, Ricoul, Michelle, Cognet, Céline, Kuilman, Thomas, Duret, Helene, Lépinasse, Florian, Marvel, Jacqueline, Verhoeyen, Els, Cosset, François-Loïc, Peeper, Daniel, Smyth, Mark J., Londoño-Vallejo, Arturo, Sabatier, Laure, Picco, Vincent, Pages, Gilles, Scoazec, Jean-Yves, Stoppacciaro, Antonella, Leonetti, Carlo, Vivier, Eric, Gilson, Eric

“…Dysfunctional telomeres suppress tumour progression by activating cell-intrinsic programs that lead to growth arrest. Increased levels of TRF2, a key factor in…”
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NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma by Mattarollo, Stephen R., West, Alison C., Steegh, Kim, Duret, Helene, Paget, Christophe, Martin, Ben, Matthews, Geoffrey M., Shortt, Jake, Chesi, Marta, Bergsagel, P. Leif, Bots, Michael, Zuber, Johannes, Lowe, Scott W., Johnstone, Ricky W., Smyth, Mark J.

“…Immunomodulators are effective in controlling hematologic malignancy by initiating or reactivating host antitumor immunity to otherwise poorly immunogenic and…”
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Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies by VERBRUGGE, Inge, HAGEKYRIAKOU, Jim, HAYNES, Nicole M, SHARP, Leslie L, GALLI, Mara, WEST, Alison, MCLAUGHLIN, Nicole M, DURET, Hélène, YAGITA, Hideo, JOHNSTONE, Ricky W, SMYTH, Mark J

“…It is becoming increasingly evident that radiotherapy may benefit from coincident or subsequent immunotherapy. In this study, we examined whether the antitumor…”
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Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells by Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip R., Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence, Kroemer, Guido

“…The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to…”
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CCL2/CCR2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy by YUTING MA, MATTAROLLO, Stephen R, YIDAN WANG, SISTIGU, Antonella, SCHULTZE, Joachim L, STOLL, Gautier, GALLUZZI, Lorenzo, ZITVOGEL, Laurence, SMYTH, Mark J, KROEMER, Guido, ADJEMIAN, Sandy, HENG YANG, AYMERIC, Laetitia, HANNANI, Dalil, PORTELA CATANI, João Paulo, DURET, Helene, TENG, Michele W. L, KEPP, Oliver

“…The therapeutic efficacy of anthracyclines relies, at least partially, on the induction of a dendritic cell- and T-lymphocyte-dependent anticancer immune…”
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Sun exposure and high preharvest fruit temperatures increase antioxidants, heat shock proteins and thermotolerance of mango fruit (Mangifera indica L.) by Kagy, Valérie, Duret, Hélène, Mangeas, Morgan, Bouteiller, Marcelle, Murcia, Irma, Pineau, René, Amir, Hamid, Brewster, Di, Olsson, Shane, White, Anne, Requejo-Jackman, Cecilia, Jackman, Richard, Thorp, Grant, Clark, Chris, Woolf, Allan B.

“…Preharvest sun-exposure can improve the tolerance of fruit during postharvest handling conditions and thus we examined the postharvest responses of mangos…”
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Role of γδ T cells in α-galactosylceramide-mediated immunity by Paget, Christophe, Chow, Melvyn T, Duret, Helene, Mattarollo, Stephen R, Smyth, Mark J

“…Attempts to harness mouse type I NKT cells in different therapeutic settings including cancer, infection, and autoimmunity have proven fruitful using the…”
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Type I NKT‐cell‐mediated TNF‐α is a positive regulator of NLRP3 inflammasome priming by Chow, Melvyn T., Duret, Helene, Andrews, Daniel M., Faveeuw, Christelle, Möller, Andreas, Smyth, Mark J., Paget, Christophe

“…The NLRP3 inflammasome plays a crucial role in the innate immune response to pathogens and exogenous or endogenous danger signals. Its activity must be…”
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Transient Foxp3+ regulatory T‐cell depletion enhances therapeutic anticancer vaccination targeting the immune‐stimulatory properties of NKT cells by Mattarollo, Stephen R, Steegh, Kim, Li, Ming, Duret, Helene, Foong Ngiow, Shin, Smyth, Mark J

“…The natural killer T (NKT) cell ligand, alpha‐galactosylceramide (α‐GalCer), represents a potential adjuvant to boost immunotherapeutic vaccination strategies…”
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Anti-IL-23 Monoclonal Antibody Synergizes in Combination with Targeted Therapies or IL-2 to Suppress Tumor Growth and Metastases by TENG, Michele W. L, VON SCHEIDT, Bianca, DURET, Helene, TOWNE, Jennifer E, SMYTH, Mark J

“…Immunosuppressive barricades erected by tumors during the evolution of immune escape represent a major obstacle to many potentially effective cancer therapies…”
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Type I NKT ‐cell‐mediated TNF ‐α is a positive regulator of NLRP 3 inflammasome priming by Chow, Melvyn T., Duret, Helene, Andrews, Daniel M., Faveeuw, Christelle, Möller, Andreas, Smyth, Mark J., Paget, Christophe

“…The NLRP 3 inflammasome plays a crucial role in the innate immune response to pathogens and exogenous or endogenous danger signals. Its activity must be…”
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Type I NKT-cell-mediated TNF-[alpha] is a positive regulator of NLRP3 inflammasome priming by Chow, Melvyn T, Duret, Helene, Andrews, Daniel M, Faveeuw, Christelle, Moller, Andreas, Smyth, Mark J, Paget, Christophe

“…The NLRP3 inflammasome plays a crucial role in the innate immune response to pathogens and exogenous or endogenous danger signals. Its activity must be…”
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Role of gamma delta T Cells in alpha -Galactosylceramide-Mediated Immunity by Paget, Christophe, Chow, Melvyn T, Duret, Helene, Mattarollo, Stephen R, Smyth, Mark J

“…Attempts to harness mouse type I NKT cells in different therapeutic settings including cancer, infection, and autoimmunity have proven fruitful using the…”
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Studying the role of the immune system on the antitumor activity of a Hedgehog inhibitor against murine osteosarcoma by Paget, Christophe, Duret, Helene, Ngiow, Shin Foong, Kansara, Maya, Thomas, David M., Smyth, Mark J.

“…Recent evidence demonstrates that the efficacy of conventional anticancer therapies including chemotherapy requires a functional immune system. Here, we…”
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Le musée face à l’art de son temps by Duret, Hélène

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