Search Results - "Durdu, Sevi"

Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia by Mazaheri, Fargol, Breus, Oksana, Durdu, Sevi, Haas, Petra, Wittbrodt, Jochen, Gilmour, Darren, Peri, Francesca

“…The removal of dying neurons by microglia has a key role during both development and in several diseases. To date, little is known about the cellular and…”
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Directional tissue migration through a self-generated chemokine gradient by Donà, Erika, Barry, Joseph D., Valentin, Guillaume, Quirin, Charlotte, Khmelinskii, Anton, Kunze, Andreas, Durdu, Sevi, Newton, Lionel R., Fernandez-Minan, Ana, Huber, Wolfgang, Knop, Michael, Gilmour, Darren

“…It is widely accepted that migrating cells and tissues navigate along pre-patterned chemoattractant gradients; here it is shown that migrating tissues can also…”
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BANP opens chromatin and activates CpG-island-regulated genes by Grand, Ralph S., Burger, Lukas, Gräwe, Cathrin, Michael, Alicia K., Isbel, Luke, Hess, Daniel, Hoerner, Leslie, Iesmantavicius, Vytautas, Durdu, Sevi, Pregnolato, Marco, Krebs, Arnaud R., Smallwood, Sébastien A., Thomä, Nicolas, Vermeulen, Michiel, Schübeler, Dirk

“…The majority of gene transcripts generated by RNA polymerase II in mammalian genomes initiate at CpG island (CGI) promoters 1 , 2 , yet our understanding of…”
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Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation by Kaluscha, Sebastian, Domcke, Silvia, Wirbelauer, Christiane, Stadler, Michael B., Durdu, Sevi, Burger, Lukas, Schübeler, Dirk

“…Cytosine methylation efficiently silences CpG-rich regulatory regions of genes and repeats in mammalian genomes. To what extent this entails direct inhibition…”
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Luminal signalling links cell communication to tissue architecture during organogenesis by Durdu, Sevi, Iskar, Murat, Revenu, Celine, Schieber, Nicole, Kunze, Andreas, Bork, Peer, Schwab, Yannick, Gilmour, Darren

“…Groups of cells within a migrating collective assemble shared luminal cavities that trap and concentrate the signalling molecule fibroblast growth factor,…”
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Readout of histone methylation by Trim24 locally restricts chromatin opening by p53 by Isbel, Luke, Iskar, Murat, Durdu, Sevi, Weiss, Joscha, Grand, Ralph S., Hietter-Pfeiffer, Eric, Kozicka, Zuzanna, Michael, Alicia K., Burger, Lukas, Thomä, Nicolas H., Schübeler, Dirk

“…The genomic binding sites of the transcription factor (TF) and tumor suppressor p53 are unusually diverse with regard to their chromatin features, including…”
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An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth by Young, Lucy C., Hartig, Nicole, Muñoz-Alegre, Marta, Oses-Prieto, Juan A., Durdu, Sevi, Bender, Sabine, Vijayakumar, Vineetha, Vietri Rudan, Matteo, Gewinner, Christina, Henderson, Stephen, Jathoul, Amit P., Ghatrora, Rupinder, Lythgoe, Mark F., Burlingame, Alma L., Rodriguez-Viciana, Pablo

“…SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the ERK-MAPK pathway, which is upregulated in the majority of human cancers…”
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Targeted Ablation Using Laser Nanosurgery by Gayathri Vegesna, Naga Venkata, Ronchi, Paolo, Durdu, Sevi, Terjung, Stefan, Pepperkok, Rainer

“…Laser-mediated dissection methods have been used for many years to micro-irradiate biological samples, but recent technological progress has rendered this…”
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A Combined ULBP2 and SEMA5A Expression Signature as a Prognostic and Predictive Biomarker for Colon Cancer by Demirkol, Secil, Gomceli, Ismail, Isbilen, Murat, Dayanc, Baris Emre, Tez, Mesut, Bostanci, Erdal Birol, Turhan, Nesrin, Akoglu, Musa, Ozyerli, Ezgi, Durdu, Sevi, Konu, Ozlen, Nissan, Aviram, Gonen, Mithat, Gure, Ali Osmay

“…Prognostic biomarkers for cancer have the power to change the course of disease if they add value beyond known prognostic factors, if they can help shape…”
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Abstract 4045: MRAS and SHOC2 interact with SCRIB and coordinate ERK pathway activation with polarity and tumorigenic growth by Young, Lucy C., Hartig, Nicole, Munoz-Alegre, Marta, Oses-Prieto, Juan A., Durdu, Sevi, Bender, Sabine, Vijakumar, Vineetha, Vietri Rudan, Matteo, Gewinner, Christina, Jathoul, Amit P., Ghatrora, Rupinder, Lythgoe, Mark L., Burlingame, Alma L., Rodriguez-Viciana, Pablo

“…Abstract SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the ERK-MAPK pathway, which is upregulated in the majority of human…”
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Abstract A22: An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth by Young, Lucy C., Hartig, Nicole, Munoz-Alegre, Marta, Oses-Prieto, Juan A., Durdu, Sevi, Bender, Sabine, Vijayakumar, Vineetha, Rudan, Matteo Vietri, Gewinner, Christina, Henderson, Stephen, Jathoul, Amit P., Ghatrora, Rupinder, Lythgoe, Mark F., Burlingame, Alma L., Rodriguez-Viciana, Pablo

“…Abstract SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the ERK-MAPK pathway, which is upregulated in the majority of human…”
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