Search Results - "Durchschlag, Helmut"
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1
Integrity of Proteins in Human Saliva after Sterilization by Gamma Irradiation
Published in Applied and Environmental Microbiology (01-02-2011)“…Microbial contamination of whole human saliva is unwanted for certain in vitro applications, e.g., when utilizing it as a growth substratum for biofilm…”
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2
Hydrodynamic multibead modeling: problems, pitfalls and solutions. 3. Comparison of new approaches for improved predictions of translational properties
Published in European biophysics journal (01-07-2013)“…Modeling simple and complex biopolymers in solution requires the shapes of these molecules to be approximated by bead modeling procedures, primarily for the…”
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3
Computational and Experimental Evidence for the Evolution of a (βα) 8-Barrel Protein from an Ancestral Quarter-Barrel Stabilised by Disulfide Bonds
Published in Journal of molecular biology (21-05-2010)“…The evolution of the prototypical (βα) 8-barrel protein imidazole glycerol phosphate synthase (HisF) was studied by complementary computational and…”
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4
Modelling of bacteriophage capsids and free nucleic acids
Published in Journal of applied crystallography (01-04-2007)“…The reconstruction of sphere shells as realized in bacteriophage capsids can be achieved by ab initio modelling approaches based on a genetic algorithm or…”
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Hydrodynamic multibead modeling: problems, pitfalls, and solutions. 2. Proteins
Published in European biophysics journal (01-02-2010)“…Hydrodynamic models of proteins have been generated by recourse to crystallographic data and applying a filling model strategy in order to predict both…”
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Hydrodynamic multibead modeling: problems, pitfalls, and solutions. 1. Ellipsoid models
Published in European biophysics journal (01-02-2010)“…The shape of macromolecules can be approximated by filling models, if both hydrodynamic and scattering properties should be predicted. Modeling of complex…”
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A comparison of protein models obtained by small-angle X-ray scattering and crystallography
Published in Journal of applied crystallography (01-12-2007)“…The technique of small‐angle scattering can be used advantageously for deriving the shape of proteins in solution. Presently, advanced ab initio approaches…”
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Modeling complex biological macromolecules: reduction of multibead models
Published in Journal of biological physics (01-12-2007)“…The shape of simple and complex biological macromolecules can be approximated by bead modeling procedures. Such approaches are required, for example, for the…”
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9
X-ray-based structural models for the in situ X-irradiation of a sulfur-containing enzyme
Published in Radiation physics and chemistry (Oxford, England : 1993) (01-08-2007)“…The X-ray damage of the sulfhydryl enzyme malate synthase from yeast has been investigated by physicochemical studies including time-resolved small-angle X-ray…”
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10
A mutation affecting the association equilibrium of formyltransferase from the hyperthermophilic Methanopyrus kandleri and its influence on the enzyme's activity and thermostability
Published in European journal of biochemistry (01-11-2000)“…Formyltransferase from Methanopyrus kandleri is composed of only one type of subunit of molecular mass 32 kDa. The enzyme is in a monomer/dimer/tetramer…”
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11
Tracking individual water molecules bound to proteins
Published in Acta crystallographica. Section A, Foundations of crystallography (16-08-2009)“…Abstract only…”
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12
Comparative investigations of biopolymer hydration by physicochemical and modeling techniques
Published in Biophysical chemistry (28-11-2001)“…The comparative investigation of biopolymer hydration by physicochemical techniques, particularly by small-angle X-ray scattering, has shown that the values…”
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13
Modeling of protein solution structures
Published in Journal of applied crystallography (01-06-2003)“…Reconstructions of low‐resolution three‐dimensional solution structures of proteins from one‐dimensional small‐angle X‐ray scattering (SAXS) data can be…”
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Journal Article Conference Proceeding -
14
X-Ray Induced Inactivation of the Sulfhydryl Enzyme Malate Synthase in the Presence of Various Additives Probing the Extent of Primary and Post-Irradiation Inactivation and Repair by Rapid Screening on the Microlevel
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-06-1990)“…The sulfhydryl enzyme malate synthase was inactivated by X-irradiation in air-saturated aqueous solution, in the absence or presence of a variety of additives…”
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15
A comparison of models for giant haemoglobins derived from different techniques
Published in Acta crystallographica. Section A, Foundations of crystallography (29-08-2010)“…Abstract only…”
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16
Modeling the hydration of proteins: prediction of structural and hydrodynamic parameters from X-ray diffraction and scattering data
Published in European biophysics journal (01-08-2003)“…The implications of protein-water interactions are of importance for understanding the solution behavior of proteins and for analyzing the fine structure of…”
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17
Small Angle X-Ray Scattering Studies and Modeling of Eudistylia vancouverii Chlorocruorin and Macrobdella decora Hemoglobin
Published in Biophysical journal (01-08-2004)“…Annelids possess giant extracellular oxygen carriers that exhibit a hexagonal bilayer appearance and have molecular masses of ∼3.5 MDa. By small angle x-ray…”
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18
Modeling of complex protein structures
Published in Physica A (01-11-2002)“…The solution structure of simple and complex proteins can be modeled efficaciously, starting either from solution scattering data or from the 3D structures…”
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Comparative investigations of the effects of X- and UV-irradiation on lysozyme in the absence or presence of additives
Published in Radiation physics and chemistry (Oxford, England : 1993) (01-06-2003)“…The radiation damage of lysozyme has been investigated in aqueous solution, after preceding X- and UV-irradiation in the absence or presence of various…”
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Prediction of structural and hydrodynamic parameters of hydrated proteins by computer modeling based on the results from high-resolution techniques
Published in Physica A (01-02-2002)“…The solution behavior of proteins is governed by their molecular characteristics and the water molecules that bind to the protein surface. Based on the 3D…”
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