Search Results - "Durbin, Joan E."
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Interferon induction and function at the mucosal surface
Published in Immunological reviews (01-09-2013)“…Summary Interferons (IFNs) are produced in response to virus infection and induce an antiviral state in virtually all cell types. In addition to upregulating…”
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2
Type III IFNs: Beyond antiviral protection
Published in Seminars in immunology (01-06-2019)“…The unexpected discovery of a novel family of antiviral mediators, type III IFNs or IFN-λs, challenged the widely accepted primacy of type I IFNs in antiviral…”
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COVID-19 and emerging viral infections: The case for interferon lambda
Published in The Journal of experimental medicine (04-05-2020)“…With the first reports on coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the…”
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Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections
Published in PLoS pathogens (29-04-2016)“…Type I (IFN-α/β) and type III (IFN-λ) interferons (IFNs) exert shared antiviral activities through distinct receptors. However, their relative importance for…”
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5
Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2016)“…Clinical observations link respiratory virus infection and Pseudomonas aeruginosa colonization in chronic lung disease, including cystic fibrosis (CF) and…”
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Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Critical role of interferons in gastrointestinal injury repair
Published in Nature communications (11-05-2021)“…The etiology of ulcerative colitis is poorly understood and is likely to involve perturbation of the complex interactions between the mucosal immune system and…”
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Induction and function of type I and III interferon in response to viral infection
Published in Current opinion in virology (01-12-2011)“…► Viral infection induces type I and III IFN through recognition of viral nucleic acid. ► Ubiquitin is a key signaling component downstream of nucleic acid…”
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Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo
Published in Journal of Virology (01-11-2010)“…Author's Correction ( vol. 85 , p. 650 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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10
An intranasal recombinant NDV-BRSV Fopt vaccine is safe and reduces lesion severity in a colostrum-deprived calf model of RSV infection
Published in Scientific reports (29-12-2022)“…Human respiratory syncytial virus (HRSV) is a major cause of severe lower respiratory tract disease in infants and the elderly, yet no safe, effective vaccine…”
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11
Animal models of respiratory syncytial virus infection and disease
Published in Current opinion in virology (01-08-2015)“…•Human RSV cannot be adapted to rodent species.•The pattern of infection seen in mice is unlike that found in the human host, infecting different cell…”
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Differential Type I Interferon Induction by Respiratory Syncytial Virus and Influenza A Virus In Vivo
Published in Journal of Virology (01-09-2007)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Contribution of type III interferons to antiviral immunity: location, location, location
Published in The Journal of biological chemistry (05-05-2017)“…Type I interferons (IFN-α/β) and the more recently identified type III IFNs (IFN-λ) function as the first line of defense against virus infection and regulate…”
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14
Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
Published in Cell cycle (Georgetown, Tex.) (01-03-2011)“…The anti-tumor function of Stat1 as a regulator of innate immunity and tumor immune surveillance has been long studied and is well understood; however, less…”
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Correction: Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections
Published in PLoS pathogens (15-06-2016)“…[This corrects the article DOI: 10.1371/journal.ppat.1005600.]…”
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Protection against Respiratory Syncytial Virus by a Recombinant Newcastle Disease Virus Vector
Published in Journal of Virology (01-02-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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17
Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
Published in Cell (09-02-1996)“…The STAT1 transcription factor is activated in response to many cytokines and growth factors. To study the requirement for STAT1 in vivo, we disrupted the…”
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STAT1 Negatively Regulates Lung Basophil IL-4 Expression Induced by Respiratory Syncytial Virus Infection
Published in The Journal of immunology (1950) (01-08-2009)“…IL-4 contributes to immunopathology induced in mice by primary respiratory syncytial virus (RSV) infection. However, the cellular source of IL-4 in RSV…”
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19
Type I IFN Modulates Innate and Specific Antiviral Immunity
Published in The Journal of immunology (1950) (15-04-2000)“…IFNs protect from virus infection by inducing an antiviral state and by modulating the immune response. Using mice deficient in multiple aspects of IFN…”
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The Role of IFN in Respiratory Syncytial Virus Pathogenesis
Published in The Journal of immunology (1950) (15-03-2002)“…Formalin-inactivated respiratory syncytial virus (RSV) vaccine preparations have been shown to cause enhanced disease in naive hosts following natural…”
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