Search Results - "Duranton, B"
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Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells
Published in The Journal of pharmacology and experimental therapeutics (01-07-2001)“…Geraniol and other monoterpenes found in essential oils of fruits and herbs have been suggested to represent a new class of agents for cancer chemoprevention…”
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Promotion of intestinal carcinogenesis by Streptococcus bovis
Published in Carcinogenesis (New York) (01-04-2000)“…The involvement of Streptococcus bovis, an member of the human gut flora, in colorectal neoplastic diseases is an object of controversy. The aim of this study…”
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Resveratrol Inhibits Intestinal Tumorigenesis and Modulates Host-Defense-Related Gene Expression in an Animal Model of Human Familial Adenomatous Polyposis
Published in Nutrition and cancer (01-01-2001)“…We studied the effect of oral administration of resveratrol, a natural constituent of grapes, on tumorigenesis in Min mice. Min mice are congenic mice…”
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Polyamine metabolism in primary human colon adenocarcinoma cells (SW480) and their lymph node metastatic derivatives (SW620)
Published in Amino acids (01-01-2003)“…The natural polyamines are multifunctional constituents of all eucaryotic cells. The objective of this work was to compare aspects of polyamine metabolism in…”
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Effect of the polyamine oxidase inactivator MDL 72527 on N(1)-(n-octanesulfonyl)spermine toxicity
Published in The international journal of biochemistry & cell biology (01-10-2000)“…N(1)-(n-octanesulfonyl)spermine (N(1)OSSpm) is a potent calmodulin antagonist. In the present work, its toxicity to DHD/K12/TRb and CaCo-2 cells, two colon…”
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Spermine cytotoxicity to human colon carcinoma-derived cells (CaCo-2)
Published in Cell biology and toxicology (01-01-2000)“…Spermine is a constituent of all vertebrate cells. Nevertheless, it exerts toxic effects if it accumulates in cells. Spermine is a natural substrate of the…”
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Cytotoxic effects of the polyamine oxidase inactivator MDL 72527 to two human colon carcinoma cell lines SW480 and SW620
Published in Cell biology and toxicology (01-01-2002)“…N1,N4-bis(2,3-butadienyl)-1,4-butanediamine (MDL 72527) was considered to be a selective inactivator of FAD-dependent tissue polyamine oxidase. Recently MDL…”
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Promotion of intestinal carcinogenesis by dietary methionine
Published in Carcinogenesis (New York) (01-03-1999)“…The metabolism of the polyamines spermidine and spermine is known to be enhanced in rapidly proliferating cells. Methionine is a precursor of the aminopropyl…”
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Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells
Published in Cancer letters (29-09-2000)“…Resveratrol, a natural polyphenolic phytoalexine present in grapes and wines, has been reported to exert a variety of important pharmacological effects. We…”
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Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis
Published in Cancer detection and prevention (2000)“…This study was performed to determine whether a single oral dose of ornithine (Orn), the substrate of ornithine decarboxylase (ODC), increases blood…”
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Inhibition of polyamine oxidase enhances the cytotoxicity of polyamine oxidase substrates. A model study with N 1-( n-octanesulfonyl)spermine and human colon cancer cells
Published in The international journal of biochemistry & cell biology (01-07-2000)“…N 1-( n-octanesulfonyl)spermine (N 1 OSSpm) is a substrate of polyamine oxidase. It shares several properties with spermine, such as antagonism of NMDA-type…”
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Concomitant Changes in Polyamine Pools and DNA Methylation during Growth Inhibition of Human Colonic Cancer Cells
Published in Experimental cell research (15-09-1998)“…The effects of CGP 48664 and DFMO, selective inhibitors of the key enzymes of polyamine biosynthesis, namely, ofS-adenosylmethionine decarboxylase (AdoMetDC)…”
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Preventive administration of ornithine alpha-ketoglutarate improves intestinal mucosal repair after transient ischemia in rats
Published in Critical care medicine (01-01-1998)“…OBJECTIVESTo investigate whether the preventive enteral administration of a polyamine precursor, such as ornithine alpha-ketoglutarate (OKG), has a beneficial…”
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Effect of the polyamine oxidase inactivator MDL 72527 on N1-(n-octanesulfonyl)spermine toxicity
Published in The international journal of biochemistry & cell biology (01-10-2000)“…N 1-(n-octanesulfonyl)spermine ( N 1OSSpm) is a potent calmodulin antagonist. In the present work, its toxicity to DHD/K12/TRb and CaCo-2 cells, two colon…”
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Journal Article -
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NO synthase inhibition promotes preneoplastic changes in the colon of rats
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-08-1999)Get full text
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Nitric Oxide Synthase Inhibition Promotes Carcinogen-Induced Preneoplastic Changes in the Colon of Rats
Published in Nitric oxide (01-12-2000)“…l-Arginine is metabolized either to polyamines through arginase and ornithine decarboxylase (ODC) activities or to citrulline and nitric oxide (NO, nitrogen…”
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Inhibition of polyamine oxidase enhances the cytotoxicity of polyamine oxidase substrates. A model study with N1-(n-octanesulfonyl)spermine and human colon cancer cells
Published in The international journal of biochemistry & cell biology (01-07-2000)“…N(1)-(n-octanesulfonyl)spermine (N(1) OSSpm) is a substrate of polyamine oxidase. It shares several properties with spermine, such as antagonism of NMDA-type…”
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Suppression of preneoplastic changes in the intestine of rats fed low levels of polyamines
Published in Cancer research (Chicago, Ill.) (15-02-1997)“…Administration for 7 days of an enteral diet that is naturally deficient in polyamines strikingly reduces the preneoplastic changes observed in the intestines…”
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P.40 Promotion of intestinal preneoplastic changes bydietary methionine
Published in Clinical nutrition (Edinburgh, Scotland) (01-08-1998)Get full text
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