Search Results - "Durant, Matthew"

Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma by Mondello, Patrizia, Tadros, Saber, Teater, Matt, Fontan, Lorena, Chang, Aaron Y, Jain, Neeraj, Yang, Haopeng, Singh, Shailbala, Ying, Hsia-Yuan, Chu, Chi-Shuen, Ma, Man Chun John, Toska, Eneda, Alig, Stefan, Durant, Matthew, de Stanchina, Elisa, Ghosh, Sreejoyee, Mottok, Anja, Nastoupil, Loretta, Neelapu, Sattva S, Weigert, Oliver, Inghirami, Giorgio, Baselga, José, Younes, Anas, Yee, Cassian, Dogan, Ahmet, Scheinberg, David A, Roeder, Robert G, Melnick, Ari M, Green, Michael R

“…mutations are highly recurrent in B-cell lymphomas and either inactivate its histone acetyltransferase (HAT) domain or truncate the protein. Herein, we show…”
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Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL by Fontan, Lorena, Goldstein, Rebecca, Casalena, Gabriella, Durant, Matthew, Teater, Matthew R., Wilson, Jimmy, Phillip, Jude, Xia, Min, Shah, Shivem, Us, Ilkay, Shinglot, Himaly, Singh, Ankur, Inghirami, Giorgio, Melnick, Ari

“…MALT1 inhibitors are promising therapeutic agents for B-cell lymphomas that are dependent on constitutive or aberrant signaling pathways. However, a potential…”
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Meiotic Cytokinesis in Saccharomyces cerevisiae : Spores That Just Need Closure by Durant, Matthew, Mucelli, Xheni, Huang, Linda S

“…In the budding yeast , sporulation occurs during starvation of a diploid cell and results in the formation of four haploid spores forming within the mother…”
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The Smk1 MAPK and Its Activator, Ssp2, Are Required for Late Prospore Membrane Development in Sporulating Saccharomyces cerevisiae by Durant, Matthew, Roesner, Joseph M, Mucelli, Xheni, Slubowski, Christian J, Klee, Erin, Seitz, Brian C, Wallis, Zoey, Huang, Linda S

“…During sporulation in the budding yeast , proper development of the prospore membrane is necessary for the formation of viable spores. The prospore membrane…”
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Physical activity of children and youth in Nova Scotia from 2001/02 and 2005/06 by Thompson, Angela M, McHugh, Tara-Leigh, Blanchard, Christopher M, Campagna, Philip D, Durant, Matthew A, Rehman, Laurene A, Murphy, Rene J.L, Wadsworth, Laurie A

“…Abstract Objectives This paper reports on physical activity of students in grades 3, 7, and 11 from two surveillance studies (from 2001 and 2005). Methods…”
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Dietary intake of Nova Scotia youth in grades 7 and 11 by Wadsworth, Laurie A, McHugh, Tara-Leigh, Thompson, Angela M, Campagna, Phillip D, Durant, Matthew A, Murphy, René J L, Rehman, Laurene A

“…We examined dietary intakes among Nova Scotia youth, and analyzed whether these intakes met existing dietary guidelines. Data from 1469 students in grades 7…”
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Molecular Choreography of Acute Exercise by Contrepois, Kévin, Wu, Si, Moneghetti, Kegan J., Hornburg, Daniel, Ahadi, Sara, Tsai, Ming-Shian, Metwally, Ahmed A., Wei, Eric, Lee-McMullen, Brittany, Quijada, Jeniffer V., Chen, Songjie, Christle, Jeffrey W., Ellenberger, Mathew, Balliu, Brunilda, Taylor, Shalina, Durrant, Matthew G., Knowles, David A., Choudhry, Hani, Ashland, Melanie, Bahmani, Amir, Enslen, Brooke, Amsallem, Myriam, Kobayashi, Yukari, Avina, Monika, Perelman, Dalia, Schüssler-Fiorenza Rose, Sophia Miryam, Zhou, Wenyu, Ashley, Euan A., Montgomery, Stephen B., Chaib, Hassan, Haddad, Francois, Snyder, Michael P.

“…Acute physical activity leads to several changes in metabolic, cardiovascular, and immune pathways. Although studies have examined selected changes in these…”
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Meiotic Cytokinesis in ISaccharomyces cerevisiae/I: Spores That Just Need Closure by Durant, Matthew, Mucelli, Xheni, Huang, Linda S

“…In the budding yeast Saccharomyces cerevisiae, sporulation occurs during starvation of a diploid cell and results in the formation of four haploid spores…”
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Meiosis II spindle disassembly requires two distinct pathways by Seitz, Brian C, Mucelli, Xheni, Majano, Maira, Wallis, Zoey, Dodge, Ashley C, Carmona, Catherine, Durant, Matthew, Maynard, Sharra, Huang, Linda S

“…During exit from meiosis II, cells undergo several structural rearrangements, including disassembly of the meiosis II spindles and cytokinesis. Each of these…”
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PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival by Lu, Xiaoqing, Fernando, Tharu M., Lossos, Chen, Yusufova, Nevin, Liu, Fan, Fontán, Lorena, Durant, Matthew, Geng, Huimin, Melnick, Jacob, Luo, Yuan, Vega, Francisco, Moy, Vincent, Inghirami, Giorgio, Nimer, Stephen, Melnick, Ari M., Lossos, Izidore S.

“…The germinal center (GC) reaction plays an important role in generating humoral immunity and is believed to give rise to most B-cell lymphomas. GC entry and…”
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Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure by Johnston, Sara C, Ricks, Keersten M, Jay, Alexandra, Raymond, Jo Lynne, Rossi, Franco, Zeng, Xiankun, Scruggs, Jennifer, Dyer, David, Frick, Ondraya, Koehler, Jeffrey W, Kuehnert, Paul A, Clements, Tamara L, Shoemaker, Charles J, Coyne, Susan R, Delp, Korey L, Moore, Joshua, Berrier, Kerry, Esham, Heather, Shamblin, Joshua, Sifford, Willie, Fiallos, Jimmy, Klosterman, Leslie, Stevens, Stephen, White, Lauren, Bowling, Philip, Garcia, Terrence, Jensen, Christopher, Ghering, Jeanean, Nyakiti, David, Bellanca, Stephanie, Kearney, Brian, Giles, Wendy, Alli, Nazira, Paz, Fabian, Akers, Kristen, Danner, Denise, Barth, James, Johnson, Joshua A, Durant, Matthew, Kim, Ruth, Hooper, Jay W, Smith, Jeffrey M, Kugelman, Jeffrey R, Beitzel, Brett F, Gibson, Kathleen M, Pitt, Margaret L M, Minogue, Timothy D, Nalca, Aysegul

“…Airborne transmission is predicted to be a prevalent route of human exposure with SARS-CoV-2. Aside from African green monkeys, nonhuman primate models that…”
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Mapping MALT1 Signaling Connectivity Unveils Novel B-Cell Feedback Mechanisms Directing Assembly of Potent Anti-Lymphoma Regimens by Fontan, Lorena, Durant, Matthew, Goldstein, Rebecca, Teater, Matthew R, Casalena, Gabriella, Xia, Min, Wilson, Jimmy, Us, Ilkay, Inghirami, Giorgio, Melnick, Ari

“…MALT1 inhibition is a promising strategy against B-cell receptor (BCR)-dependent lymphomas including ABC DLBCL, CLL and MCL. MALT1 is downstream of the most…”
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Chemically Induced Degradation of MALT1 to Treat B-Cell Lymphomas by Fontan, Lorena, Hatcher, John, Scott, David, Qiao, Qi, Us, Ilkay, Du, Guangyan, Durant, Matthew, Wilson, Jimmy, Wu, Hao, Gray, Nathanael, Melnick, Ari

“…MALT1 is a protease and scaffold protein involved in signal transduction to NF-κB downstream of several receptors including B-cell (BCR) and T-cell receptors…”
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Abstract 797: Targeting HDAC3 reactivates immunosurveillance and enhances immunocheckpoint activity in B-cell lymphoma by Mondello, Patrizia, Teater, Matt, Fontan, Lorena, Durant, Matthew, Stanchina, Elisa de, Inghirami, Giorgio, Green, Michael, Melnick, Ari

“…Somatic mutation of the histone acetyltransferase CREBBP occurs in ~40% of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) patients. CREBBP…”
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A Comparison of Energy Provision by Diet Order in a Long-Term Care Facility by Durant, Matthew

“…Involuntary weight loss (IWL) is common in the North American elderly population and affects as many as 60 per cent of nursing home residents, representing a…”
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Abstract LB-303: Substrate-mimetic covalent inhibitor of MALT1 is most effective against CARD11 mutant ABC-DLBCL by Fontan, Lorena, Scott, David, Hatcher, John, Qiao, Qi, Us, Ilkay, Casalena, Gabriella, Bekkers, Mariette, Philippar, Ulrike, Durant, Matthew, Chennamadhavuni, Spandan, Wu, Hao, Gray, Nathaniel, Melnick, Ari

“…Diffuse Large B-cell lymphoma is the most common subtype of B-cell non Hodgkin Lymphoma (B-NHL) representing 30% of all B-NHL. There are three molecular…”
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Overweight Nova Scotia Children and Youth: The Roles of Household Income and Adherence to Canada's Food Guide to Healthy Eating by St John, Meredith, Durant, Matthew, Campagna, Phil D., Rehman, Laurene A., Thompson, Angela M., Wadsworth, Laurie A., Murphy, René J.L.

“…Objective: Poor diet quality has been observed in Nova Scotia children and youth, characterized by low intake from the traditional four food groups and a high…”
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Does availability of recreation facilities create more active children? by Rehman, Laurene, PhD, Campagna, Phil, PhD, Durant, Matthew, Murphy, Rene, Rainham, Daniel, Thompson, Angela, Wadsworth, Laurie

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Physical activity and body mass index of children and youth in the province of nova scotia 2001/02 and 2005/06 by Thompson, Angela M, Campagna, Philip D, Durant, Matthew, Murphy, Rene J.L, Rehman, Laurene A, Wadsworth, Laurie A

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Breakfast consumption habits and self-perceived weight concerns of Grade 7 and 11 nova scotia students point to new opportunities for public health intervention by BSc, Meredith St. John, Durant, Matthew, Wadsworth, Laurie A, Thompson, Angela M, Rehman, Laurene A, Campagna, Philip D, Murphy, René J.L

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