Search Results - "Durand, Sylvère"

Transmission of innate immune signaling by packaging of cGAMP in viral particles by Gentili, Matteo, Kowal, Joanna, Tkach, Mercedes, Satoh, Takeshi, Lahaye, Xavier, Conrad, Cécile, Boyron, Marilyn, Lombard, Bérangère, Durand, Sylvère, Kroemer, Guido, Loew, Damarys, Dalod, Marc, Théry, Clotilde, Manel, Nicolas

“…Infected cells detect viruses through a variety of receptors that initiate cell-intrinsic innate defense responses. Cyclic guanosine monophosphate…”
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Crizotinib-induced immunogenic cell death in non-small cell lung cancer by Liu, Peng, Zhao, Liwei, Pol, Jonathan, Levesque, Sarah, Petrazzuolo, Adriana, Pfirschke, Christina, Engblom, Camilla, Rickelt, Steffen, Yamazaki, Takahiro, Iribarren, Kristina, Senovilla, Laura, Bezu, Lucillia, Vacchelli, Erika, Sica, Valentina, Melis, Andréa, Martin, Tiffany, Xia, Lin, Yang, Heng, Li, Qingqing, Chen, Jinfeng, Durand, Sylvère, Aprahamian, Fanny, Lefevre, Deborah, Broutin, Sophie, Paci, Angelo, Bongers, Amaury, Minard-Colin, Veronique, Tartour, Eric, Zitvogel, Laurence, Apetoh, Lionel, Ma, Yuting, Pittet, Mikael J., Kepp, Oliver, Kroemer, Guido

“…Immunogenic cell death (ICD) converts dying cancer cells into a therapeutic vaccine and stimulates antitumor immune responses. Here we unravel the results of…”
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Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance by Pietrocola, Federico, Pol, Jonathan, Vacchelli, Erika, Rao, Shuan, Enot, David P., Baracco, Elisa E., Levesque, Sarah, Castoldi, Francesca, Jacquelot, Nicolas, Yamazaki, Takahiro, Senovilla, Laura, Marino, Guillermo, Aranda, Fernando, Durand, Sylvère, Sica, Valentina, Chery, Alexis, Lachkar, Sylvie, Sigl, Verena, Bloy, Norma, Buque, Aitziber, Falzoni, Simonetta, Ryffel, Bernhard, Apetoh, Lionel, Di Virgilio, Francesco, Madeo, Frank, Maiuri, Maria Chiara, Zitvogel, Laurence, Levine, Beth, Penninger, Josef M., Kroemer, Guido

“…Caloric restriction mimetics (CRMs) mimic the biochemical effects of nutrient deprivation by reducing lysine acetylation of cellular proteins, thus triggering…”
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Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer by Buqué, Aitziber, Bloy, Norma, Perez-Lanzón, Maria, Iribarren, Kristina, Humeau, Juliette, Pol, Jonathan G., Levesque, Sarah, Mondragon, Laura, Yamazaki, Takahiro, Sato, Ai, Aranda, Fernando, Durand, Sylvère, Boissonnas, Alexandre, Fucikova, Jitka, Senovilla, Laura, Enot, David, Hensler, Michal, Kremer, Margerie, Stoll, Gautier, Hu, Yang, Massa, Chiara, Formenti, Silvia C., Seliger, Barbara, Elemento, Olivier, Spisek, Radek, André, Fabrice, Zitvogel, Laurence, Delaloge, Suzette, Kroemer, Guido, Galluzzi, Lorenzo

“…Hormone receptor (HR) + breast cancer (BC) causes most BC-related deaths, calling for improved therapeutic approaches. Despite expectations, immune checkpoint…”
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Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism by Bárcena, Clea, Quirós, Pedro M., Durand, Sylvère, Mayoral, Pablo, Rodríguez, Francisco, Caravia, Xurde M., Mariño, Guillermo, Garabaya, Cecilia, Fernández-García, María Teresa, Kroemer, Guido, Freije, José M.P., López-Otín, Carlos

“…Dietary intervention constitutes a feasible approach for modulating metabolism and improving the health span and lifespan. Methionine restriction (MR) delays…”
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Diagnostic, Prognostic and Mechanistic Biomarkers of COVID-19 Identified by Mass Spectrometric Metabolomics by Bourgin, Mélanie, Durand, Sylvère, Kroemer, Guido

“…A number of studies have assessed the impact of SARS-CoV-2 infection and COVID-19 severity on the metabolome of exhaled air, saliva, plasma, and urine to…”
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Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers by Danlos, François-Xavier, Grajeda-Iglesias, Claudia, Durand, Sylvère, Sauvat, Allan, Roumier, Mathilde, Cantin, Delphine, Colomba, Emeline, Rohmer, Julien, Pommeret, Fanny, Baciarello, Giulia, Willekens, Christophe, Vasse, Marc, Griscelli, Frank, Fahrner, Jean-Eudes, Goubet, Anne-Gaëlle, Dubuisson, Agathe, Derosa, Lisa, Nirmalathasan, Nitharsshini, Bredel, Delphine, Mouraud, Séverine, Pradon, Caroline, Stoclin, Annabelle, Rozenberg, Flore, Duchemin, Jérôme, Jourdi, Georges, Ellouze, Syrine, Levavasseur, Françoise, Albigès, Laurence, Soria, Jean-Charles, Barlesi, Fabrice, Solary, Eric, André, Fabrice, Pène, Frédéric, Ackerman, Félix, Mouthon, Luc, Zitvogel, Laurence, Marabelle, Aurélien, Michot, Jean-Marie, Fontenay, Michaela, Kroemer, Guido

“…The circulating metabolome provides a snapshot of the physiological state of the organism responding to pathogenic challenges. Here we report alterations in…”
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Influence of microbiota-associated metabolic reprogramming on clinical outcome in patients with melanoma from the randomized adjuvant dendritic cell-based MIND-DC trial by Alves Costa Silva, Carolina, Piccinno, Gianmarco, Suissa, Déborah, Bourgin, Mélanie, Schreibelt, Gerty, Durand, Sylvère, Birebent, Roxanne, Fidelle, Marine, Sow, Cissé, Aprahamian, Fanny, Manghi, Paolo, Punčochář, Michal, Asnicar, Francesco, Pinto, Federica, Armanini, Federica, Terrisse, Safae, Routy, Bertrand, Drubay, Damien, Eggermont, Alexander M. M., Kroemer, Guido, Segata, Nicola, Zitvogel, Laurence, Derosa, Lisa, Bol, Kalijn F., de Vries, I. Jolanda M.

“…Tumor immunosurveillance plays a major role in melanoma, prompting the development of immunotherapy strategies. The gut microbiota composition, influencing…”
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Chemical activation of SAT1 corrects diet-induced metabolic syndrome by Castoldi, Francesca, Hyvönen, Mervi T., Durand, Sylvère, Aprahamian, Fanny, Sauvat, Allan, Malik, Shoaib A., Baracco, Elisa Elena, Vacchelli, Erika, Opolon, Paule, Signolle, Nicolas, Lefevre, Déborah, Bossut, Noelie, Eisenberg, Tobias, Dammbrueck, Christopher, Pendl, Tobias, Kremer, Margerie, Lachkar, Sylvie, Einer, Claudia, Michalke, Bernhard, Zischka, Hans, Madeo, Frank, Keinänen, Tuomo A., Maiuri, Maria Chiara, Pietrocola, Federico, Kroemer, Guido

“…The pharmacological targeting of polyamine metabolism is currently under the spotlight for its potential in the prevention and treatment of several…”
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3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis by Cerrato, Giulia, Alvarez-Lucena, Carlota, Sauvat, Allan, Hu, Yanhua, Forveille, Sabrina, Chen, Guo, Durand, Sylvère, Aprahamian, Fanny, Leduc, Marion, Motiño, Omar, Boscá, Lisardo, Xu, Qingbo, Kepp, Oliver, Kroemer, Guido

“…Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing…”
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Metabolic effects of fasting on human and mouse blood in vivo by Pietrocola, Federico, Demont, Yohann, Castoldi, Francesca, Enot, David, Durand, Sylvère, Semeraro, Michaela, Baracco, Elisa Elena, Pol, Jonathan, Bravo-San Pedro, Jose Manuel, Bordenave, Chloé, Levesque, Sarah, Humeau, Juliette, Chery, Alexis, Métivier, Didier, Madeo, Frank, Maiuri, M. Chiara, Kroemer, Guido

“…Starvation is a strong physiological stimulus of macroautophagy/autophagy. In this study, we addressed the question as to whether it would be possible to…”
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Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate by Sica, Valentina, Bravo-San Pedro, Jose Manuel, Izzo, Valentina, Pol, Jonathan, Pierredon, Sandra, Enot, David, Durand, Sylvère, Bossut, Noélie, Chery, Alexis, Souquere, Sylvie, Pierron, Gerard, Vartholomaiou, Evangelia, Zamzami, Naoufal, Soussi, Thierry, Sauvat, Allan, Mondragón, Laura, Kepp, Oliver, Galluzzi, Lorenzo, Martinou, Jean-Claude, Hess-Stumpp, Holger, Ziegelbauer, Karl, Kroemer, Guido, Maiuri, Maria Chiara

“…Inhibition of oxidative phosphorylation (OXPHOS)…”
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Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy by Wu, Qi, Tian, Ai-Ling, Durand, Sylvère, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Xie, Wei, Liu, Peng, Zhao, Liwei, Zhang, Shuai, Pan, Hui, Carmona-Gutierrez, Didac, Madeo, Frank, Tu, Yi, Kepp, Oliver, Kroemer, Guido

“…A number of natural plant products have a long-standing history in both traditional and modern medical applications. Some secondary metabolites induce…”
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The metabolomic signature of extreme longevity: naked mole rats versus mice by Viltard, Mélanie, Durand, Sylvère, Pérez-Lanzón, Maria, Aprahamian, Fanny, Lefevre, Deborah, Leroy, Christine, Madeo, Frank, Kroemer, Guido, Friedlander, Gérard

“…The naked mole-rat ( ) is characterized by a more than tenfold higher life expectancy compared to another rodent species of the same size, namely, the…”
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An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABAA receptor by Anagnostopoulos, Gerasimos, Motiño, Omar, Li, Sijing, Carbonnier, Vincent, Chen, Hui, Sica, Valentina, Durand, Sylvère, Bourgin, Mélanie, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Donne, Romain, Desdouets, Chantal, Sola, Marcelo Simon, Kotta, Konstantina, Montégut, Léa, Lambertucci, Flavia, Surdez, Didier, Sandrine, Grossetête, Delattre, Olivier, Maiuri, Maria Chiara, Bravo-San Pedro, José Manuel, Martins, Isabelle, Kroemer, Guido

“…Acyl-coenzyme-A-binding protein (ACBP), also known as a diazepam-binding inhibitor (DBI), is a potent stimulator of appetite and lipogenesis. Bioinformatic…”
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Modulation of the Bile Acid Enterohepatic Cycle by Intestinal Microbiota Alleviates Alcohol Liver Disease by Ciocan, Dragos, Spatz, Madeleine, Trainel, Nicolas, Hardonnière, Kévin, Domenichini, Séverine, Mercier-Nomé, Françoise, Desmons, Aurore, Humbert, Lydie, Durand, Sylvère, Kroemer, Guido, Lamazière, Antonin, Hugot, Cindy, Perlemuter, Gabriel, Cassard, Anne-Marie

“…Reshaping the intestinal microbiota by the ingestion of fiber, such as pectin, improves alcohol-induced liver lesions in mice by modulating bacterial…”
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Glucose Metabolism and Metabolomic Changes in Response to Prolonged Fasting in Individuals with Obesity, Type 2 Diabetes and Non-Obese People-A Cohort Trial by Tripolt, Norbert J, Hofer, Sebastian J, Pferschy, Peter N, Aziz, Faisal, Durand, Sylvère, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Waltenstorfer, Mara, Eisenberg, Tobias, Obermayer, Anna M A, Riedl, Regina, Kojzar, Harald, Moser, Othmar, Sourij, Caren, Bugger, Heiko, Oulhaj, Abderrahim, Pieber, Thomas R, Zanker, Matthias, Kroemer, Guido, Madeo, Frank, Sourij, Harald

“…Metabolic regulation of glucose can be altered by fasting periods. We examined glucose metabolism and metabolomics profiles after 12 h and 36 h fasting in…”
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Multifaceted modes of action of the anticancer probiotic Enterococcus hirae by Goubet, Anne-Gaëlle, Wheeler, Richard, Fluckiger, Aurélie, Qu, Bo, Lemaître, Fabien, Iribarren, Kristina, Mondragón, Laura, Tidjani Alou, Maryam, Pizzato, Eugénie, Durand, Sylvère, Derosa, Lisa, Aprahamian, Fanny, Bossut, Noélie, Moya-Nilges, Maryse, Derrien, Diane, Chen, Guo, Leduc, Marion, Joseph, Adrien, Pons, Nicolas, Le Chatelier, Emmanuelle, Segata, Nicola, Yonekura, Satoru, Iebba, Valerio, Kepp, Oliver, Raoult, Didier, André, Fabrice, Kroemer, Guido, Boneca, Ivo Gomperts, Zitvogel, Laurence, Daillère, Romain

“…A deviated repertoire of the gut microbiome predicts resistance to cancer immunotherapy. Enterococcus hirae compensated cancer-associated dysbiosis in various…”
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Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo by Enot, David P., Niso-Santano, Mireia, Durand, Sylvère, Chery, Alexis, Pietrocola, Federico, Vacchelli, Erika, Madeo, Frank, Galluzzi, Lorenzo, Kroemer, Guido

“…Recently, we reported that saturated and unsaturated fatty acids trigger autophagy through distinct signal transduction pathways. Saturated fatty acids like…”
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Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors by Tran, Bao-Tram Thi, Gelin, Aurore, Durand, Sylvère, Texier, Matthieu, Daste, Amaury, Toullec, Clémence, Benihoud, Karim, Breuskin, Ingrid, Gorphe, Philippe, Garic, Florence, Brenner, Catherine, Le Tourneau, Christophe, Fayette, Jérôme, Niki, Toshiro, David, Muriel, Busson, Pierre, Even, Caroline

“…Extra-cellular galectins 1, 3 and 9 (gal-1, -3 and -9) are known to act as soluble immunosuppressive agents in various malignancies. Previous publications have…”
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