Search Results - "Durand, Sarah C"

Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase Sensing in Human Hepatocytes by Verrier, Eloi R., Yim, Seung‐Ae, Heydmann, Laura, El Saghire, Houssein, Bach, Charlotte, Turon‐Lagot, Vincent, Mailly, Laurent, Durand, Sarah C., Lucifora, Julie, Durantel, David, Pessaux, Patrick, Manel, Nicolas, Hirsch, Ivan, Zeisel, Mirjam B., Pochet, Nathalie, Schuster, Catherine, Baumert, Thomas F.

“…Chronic hepatitis B virus (HBV) infection is a major cause of chronic liver disease and cancer worldwide. The mechanisms of viral genome sensing and the…”
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A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses by Verrier, Eloi R., Colpitts, Che C., Bach, Charlotte, Heydmann, Laura, Weiss, Amélie, Renaud, Mickaël, Durand, Sarah C., Habersetzer, François, Durantel, David, Abou‐Jaoudé, Georges, López Ledesma, Maria M., Felmlee, Daniel J., Soumillon, Magali, Croonenborghs, Tom, Pochet, Nathalie, Nassal, Michael, Schuster, Catherine, Brino, Laurent, Sureau, Camille, Zeisel, Mirjam B., Baumert, Thomas F.

“…Chronic hepatitis B and D infections are major causes of liver disease and hepatocellular carcinoma worldwide. Efficient therapeutic approaches for cure are…”
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Humanisation of a claudin-1-specific monoclonal antibody for clinical prevention and cure of HCV infection without escape by Colpitts, Che C, Tawar, Rajiv G, Mailly, Laurent, Thumann, Christine, Heydmann, Laura, Durand, Sarah C, Xiao, Fei, Robinet, Eric, Pessaux, Patrick, Zeisel, Mirjam B, Baumert, Thomas F

“…HCV infection is a leading cause of chronic liver disease and a major indication for liver transplantation. Although direct-acting antivirals (DAAs) have much…”
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Epidermal growth factor receptor signaling impairs the antiviral activity of interferon‐alpha by Lupberger, Joachim, Duong, François H.T., Fofana, Isabel, Zona, Laetitia, Xiao, Fei, Thumann, Christine, Durand, Sarah C., Pessaux, Patrick, Zeisel, Mirjam B., Heim, Markus H., Baumert, Thomas F.

“…Interferon‐alpha (IFN‐α) exhibits its antiviral activity through signal transducer and activator of transcription protein (STAT) signaling and the expression…”
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Functional Analysis of Claudin-6 and Claudin-9 as Entry Factors for Hepatitis C Virus Infection of Human Hepatocytes by Using Monoclonal Antibodies by Fofana, Isabel, Zona, Laetitia, Thumann, Christine, Heydmann, Laura, Durand, Sarah C, Lupberger, Joachim, Blum, Hubert E, Pessaux, Patrick, Gondeau, Claire, Reynolds, Gary M, McKeating, Jane A, Grunert, Fritz, Thompson, John, Zeisel, Mirjam B, Baumert, Thomas F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus–Infected Cells and Liver to Identify Pathways Associated With Disease Development by Lupberger, Joachim, Croonenborghs, Tom, Roca Suarez, Armando Andres, Van Renne, Nicolaas, Jühling, Frank, Oudot, Marine A., Virzì, Alessia, Bandiera, Simonetta, Jamey, Carole, Meszaros, Gergö, Brumaru, Daniel, Mukherji, Atish, Durand, Sarah C., Heydmann, Laura, Verrier, Eloi R., El Saghire, Hussein, Hamdane, Nourdine, Bartenschlager, Ralf, Fereshetian, Shaunt, Ramberger, Evelyn, Sinha, Rileen, Nabian, Mohsen, Everaert, Celine, Jovanovic, Marko, Mertins, Philipp, Carr, Steven A., Chayama, Kazuaki, Dali-Youcef, Nassim, Ricci, Romeo, Bardeesy, Nabeel M., Fujiwara, Naoto, Gevaert, Olivier, Zeisel, Mirjam B., Hoshida, Yujin, Pochet, Nathalie, Baumert, Thomas F.

“…The mechanisms of hepatitis C virus (HCV) infection, liver disease progression, and hepatocarcinogenesis are only partially understood. We performed genomic,…”
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Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis by Bandiera, Simonetta, Pernot, Sophie, El Saghire, Hussein, Durand, Sarah C, Thumann, Christine, Crouchet, Emilie, Ye, Tao, Fofana, Isabel, Oudot, Marine A, Barths, Jochen, Schuster, Catherine, Pessaux, Patrick, Heim, Markus H, Baumert, Thomas F, Zeisel, Mirjam B

“…Hepatitis C virus (HCV)-induced chronic liver disease is a leading cause of hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying HCC…”
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Targeting the liver clock improves fibrosis by restoring TGF-β signaling by Crouchet, Emilie, Dachraoui, Mayssa, Jühling, Frank, Roehlen, Natascha, Oudot, Marine A., Durand, Sarah C., Ponsolles, Clara, Gadenne, Cloé, Meiss-Heydmann, Laura, Moehlin, Julien, Martin, Romain, Brignon, Nicolas, Del Zompo, Fabio, Teraoka, Yuji, Aikata, Hiroshi, Abe-Chayama, Hiromi, Chayama, Kazuaki, Saviano, Antonio, Heide, Danijela, Onea, Mihaela, Geyer, Lucas, Wolf, Thibaut, Felli, Emanuele, Pessaux, Patrick, Heikenwälder, Mathias, Chambon, Pierre, Schuster, Catherine, Lupberger, Joachim, Mukherji, Atish, Baumert, Thomas F.

“…Liver fibrosis is the major driver of hepatocellular carcinoma and liver disease-related death. Approved antifibrotic therapies are absent and compounds in…”
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Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment by Roehlen, Natascha, Muller, Marion, Nehme, Zeina, Crouchet, Emilie, Jühling, Frank, Del Zompo, Fabio, Cherradi, Sara, Duong, Francois H.T., Almeida, Nuno, Saviano, Antonio, Fernández-Vaquero, Mirian, Riedl, Tobias, El Saghire, Houssein, Durand, Sarah C., Ponsolles, Clara, Oudot, Marine A., Martin, Romain, Brignon, Nicolas, Felli, Emanuele, Pessaux, Patrick, Lallement, Antonin, Davidson, Irwin, Bandiera, Simonetta, Thumann, Christine, Marchand, Patrice, Moll, Solange, Nicolay, Brandon, Bardeesy, Nabeel, Hoshida, Yujin, Heikenwälder, Mathias, Iacone, Roberto, Toso, Alberto, Meyer, Markus, Elson, Greg, Schweighoffer, Tamas, Teixeira, Geoffrey, Zeisel, Mirjam B., Laquerriere, Patrice, Lupberger, Joachim, Schuster, Catherine, Mailly, Laurent, Baumert, Thomas F.

“…Despite recent approvals, the response to treatment and prognosis of patients with advanced hepatocellular carcinoma (HCC) remain poor. Claudin-1 (CLDN1) is a…”
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Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity by Herzog, Katharina, Bandiera, Simonetta, Pernot, Sophie, Fauvelle, Catherine, Jühling, Frank, Weiss, Amélie, Bull, Anne, Durand, Sarah C, Chane-Woon-Ming, Béatrice, Pfeffer, Sébastien, Mercey, Marion, Lerat, Hervé, Meunier, Jean-Christophe, Raffelsberger, Wolfgang, Brino, Laurent, Baumert, Thomas F, Zeisel, Mirjam B

“…Infection of human hepatocytes by the hepatitis C virus (HCV) is a multistep process involving both viral and host factors. microRNAs (miRNAs) are small…”
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An atlas of the human liver diurnal transcriptome and its perturbation by hepatitis C virus infection by Mukherji, Atish, Jühling, Frank, Simanjuntak, Yogy, Crouchet, Emilie, Del Zompo, Fabio, Teraoka, Yuji, Haller, Alexandre, Baltzinger, Philippe, Paritala, Soumith, Rasha, Fahmida, Fujiwara, Naoto, Gadenne, Cloé, Slovic, Nevena, Oudot, Marine A., Durand, Sarah C., Ponsolles, Clara, Schuster, Catherine, Zhuang, Xiaodong, Holmes, Jacinta, Yeh, Ming-Lun, Abe-Chayama, Hiromi, Heikenwälder, Mathias, Sangiovanni, Angelo, Iavarone, Massimo, Colombo, Massimo, Foung, Steven K. H., McKeating, Jane A., Davidson, Irwin, Yu, Ming-Lung, Chung, Raymond T., Hoshida, Yujin, Chayama, Kazuaki, Lupberger, Joachim, Baumert, Thomas F.

“…Chronic liver disease and cancer are global health challenges. The role of the circadian clock as a regulator of liver physiology and disease is well…”
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IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies by Duong, Francois H T, Trincucci, Gaia, Boldanova, Tujana, Calabrese, Diego, Campana, Benedetta, Krol, Ilona, Durand, Sarah C, Heydmann, Laura, Zeisel, Mirjam B, Baumert, Thomas F, Heim, Markus H

“…The molecular mechanisms that link IFN-λ3 genotypes to differential induction of interferon (IFN)-stimulated genes (ISGs) in the liver of patients with chronic…”
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HRas Signal Transduction Promotes Hepatitis C Virus Cell Entry by Triggering Assembly of the Host Tetraspanin Receptor Complex by Zona, Laetitia, Lupberger, Joachim, Sidahmed-Adrar, Nazha, Thumann, Christine, Harris, Helen J., Barnes, Amy, Florentin, Jonathan, Tawar, Rajiv G., Xiao, Fei, Turek, Marine, Durand, Sarah C., Duong, François H.T., Heim, Markus H., Cosset, François-Loïc, Hirsch, Ivan, Samuel, Didier, Brino, Laurent, Zeisel, Mirjam B., Le Naour, François, McKeating, Jane A., Baumert, Thomas F.

“…Hepatitis C virus (HCV) entry is dependent on coreceptor complex formation between the tetraspanin superfamily member CD81 and the tight junction protein…”
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Hepatitis B virus compartmentalization and single-cell differentiation in hepatocellular carcinoma by Jühling, Frank, Saviano, Antonio, Ponsolles, Clara, Heydmann, Laura, Crouchet, Emilie, Durand, Sarah C, El Saghire, Houssein, Felli, Emanuele, Lindner, Véronique, Pessaux, Patrick, Pochet, Nathalie, Schuster, Catherine, Verrier, Eloi R, Baumert, Thomas F

“…Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC) world-wide. The molecular mechanisms of viral hepatocarcinogenesis…”
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Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation by Crouchet, Emilie, Li, Shen, Sojoodi, Mozhdeh, Bandiera, Simonetta, Fujiwara, Naoto, El Saghire, Hussein, Zhu, Shijia, Qian, Tongqi, Rasha, Fahmida Akter, Del Zompo, Fabio, Barrett, Stephen C., Schaeffer, Eugénie, Oudot, Marine A., Ponsolles, Clara, Durand, Sarah C., Ghoshal, Sarani, Arora, Gunisha, Giannone, Fabio, Chung, Raymond T., Slovic, Nevena, Van Renne, Nicolaas, Felli, Emanuele, Pessaux, Patrick, Lupberger, Joachim, Pochet, Nathalie, Schuster, Catherine, Tanabe, Kenneth K., Hoshida, Yujin, Fuchs, Bryan C., Baumert, Thomas F.

“…Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients, for which chemopreventive strategies are lacking. Recently, we developed a…”
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A human liver cell atlas reveals heterogeneity and epithelial progenitors by Aizarani, Nadim, Saviano, Antonio, Sagar, Mailly, Laurent, Durand, Sarah, Herman, Josip S., Pessaux, Patrick, Baumert, Thomas F., Grün, Dominic

“…The human liver is an essential multifunctional organ. The incidence of liver diseases is rising and there are limited treatment options. However, the cellular…”
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A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery by Crouchet, Emilie, Bandiera, Simonetta, Fujiwara, Naoto, Li, Shen, El Saghire, Hussein, Fernández-Vaquero, Mirian, Riedl, Tobias, Sun, Xiaochen, Hirschfield, Hadassa, Jühling, Frank, Zhu, Shijia, Roehlen, Natascha, Ponsolles, Clara, Heydmann, Laura, Saviano, Antonio, Qian, Tongqi, Venkatesh, Anu, Lupberger, Joachim, Verrier, Eloi R., Sojoodi, Mozhdeh, Oudot, Marine A., Duong, François H. T., Masia, Ricard, Wei, Lan, Thumann, Christine, Durand, Sarah C., González-Motos, Victor, Heide, Danijela, Hetzer, Jenny, Nakagawa, Shigeki, Ono, Atsushi, Song, Won-Min, Higashi, Takaaki, Sanchez, Roberto, Kim, Rosa S., Bian, C. Billie, Kiani, Karun, Croonenborghs, Tom, Subramanian, Aravind, Chung, Raymond T., Straub, Beate K., Schuppan, Detlef, Ankavay, Maliki, Cocquerel, Laurence, Schaeffer, Evelyne, Goossens, Nicolas, Koh, Anna P., Mahajan, Milind, Nair, Venugopalan D., Gunasekaran, Ganesh, Schwartz, Myron E., Bardeesy, Nabeel, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Felli, Emanuele, Pessaux, Patrick, Tanabe, Kenneth K., Heikenwälder, Mathias, Schuster, Catherine, Pochet, Nathalie, Zeisel, Mirjam B., Fuchs, Bryan C., Hoshida, Yujin, Baumert, Thomas F.

“…Chronic liver disease and hepatocellular carcinoma (HCC) are life-threatening diseases with limited treatment options. The lack of clinically…”
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A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity by Roehlen, Natascha, Saviano, Antonio, El Saghire, Houssein, Crouchet, Emilie, Nehme, Zeina, Del Zompo, Fabio, Jühling, Frank, Oudot, Marine A, Durand, Sarah C, Duong, François H T, Cherradi, Sara, Gonzalez Motos, Victor, Almeida, Nuno, Ponsolles, Clara, Heydmann, Laura, Ostyn, Tessa, Lallement, Antonin, Pessaux, Patrick, Felli, Emanuele, Cavalli, Andrea, Sgrignani, Jacopo, Thumann, Christine, Koutsopoulos, Olga, Fuchs, Bryan C, Hoshida, Yujin, Hofmann, Maike, Vyberg, Mogens, Viuff, Birgitte Martine, Galsgaard, Elisabeth D, Elson, Greg, Toso, Alberto, Meyer, Markus, Iacone, Roberto, Schweighoffer, Tamas, Teixeira, Geoffrey, Moll, Solange, De Vito, Claudio, Roskams, Tania, Davidson, Irwin, Heide, Danijela, Heikenwälder, Mathias, Zeisel, Mirjam B, Lupberger, Joachim, Mailly, Laurent, Schuster, Catherine, Baumert, Thomas F

“…Tissue fibrosis is a key driver of end-stage organ failure and cancer, overall accounting for up to 45% of deaths in developed countries. There is a large…”
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A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response by Crouchet, Emilie, Almeida, Nuno, Durand, Sarah C., Parnot, Marie, Oudot, Marine A., Giannone, Fabio, Gadenne, Cloé, Roehlen, Natascha, Saviano, Antonio, Felli, Emanuele, Pessaux, Patrick, Duong, Huong Tuan F., Ohdan, Hideki, Aikata, Hiroshi, Chayama, Kazuaki, Baumert, Thomas F., Schuster, Catherine

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Hepatitis B virus evasion from cGAS sensing in human hepatocytes by Verrier, Eloi R., Yim, Seung-Ae, Heydmann, Laura, El Saghire, Houssein, Bach, Charlotte, Turon-Lagot, Vincent, Mailly, Laurent, Durand, Sarah C., Lucifora, Julie, Durantel, David, Pessaux, Patrick, Manel, Nicolas, Hirsch, Ivan, Zeisel, Mirjam B., Pochet, Nathalie, Schuster, Catherine, Baumert, Thomas F.

“…Chronic hepatitis B virus (HBV) infection is a major cause of chronic liver disease and cancer worldwide. The mechanisms of viral genome sensing and the…”
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