Search Results - "Durand, Nathalie"
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Bioorthogonal Conjugation of Transition Organometallic Complexes to Peptides and Proteins: Strategies and Applications
Published in European journal of inorganic chemistry (09-01-2020)“…The advent of bioorthogonal chemistry has revolutionized the common practices in protein bioconjugation and contributed to a large extent to the development of…”
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A Solvent‐free, Catalyst‐free Formal [3+3] Cycloaddition Dearomatization Strategy: Towards New Fluorophores for Biomolecules Labelling
Published in ChemSusChem (22-04-2021)“…A general, sustainable dearomatization reaction for nitrogen‐containing heterocycles was developed. Under solvent free conditions and without catalyst, the…”
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‘Clickable’ cyclopentadienyl iron carbonyl complexes for bioorthogonal conjugation of mid‐infrared labels to a model protein and PAMAM dendrimer
Published in Applied organometallic chemistry (01-04-2019)“…Owing to the intrinsic limitations of the conventional bioconjugation methods involving native nucleophilic functions of proteins, we sought to develop…”
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Inverse electron‐demand Diels‐Alder (iEDDA) bioorthogonal conjugation of half‐sandwich transition metallocarbonyl entities to a model protein
Published in Applied organometallic chemistry (01-04-2020)“…Novel transition metallocarbonyl complexes carrying a norbornene or an oxanorbornene group were synthesized by [4 + 2] cycloaddition between the organometallic…”
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Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of Its Oxidized Derivatives
Published in Molecules (Basel, Switzerland) (08-10-2022)“…The first fluorescent ferrociphenol derivative (P797) has been synthesized via McMurry cross-coupling followed by copper-catalyzed [3 + 2] azide-alkyne…”
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The Use of Glycidol to Introduce Aldehyde Functions Into Proteins - Application to the Fluorescent Labelling of Bovine Serum Albumin and Avidin
Published in European Journal of Organic Chemistry (01-11-2007)“…The reactions between 2,3‐epoxypropan‐1‐ol (glycidol) and either the nonglycosylated protein bovine serum albumin (BSA) or the glycoprotein avidin (AV) allowed…”
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Synthesis of Metal-Carbonyl-Dendrimer-Antibody Immunoconjugates: Towards a New Format for Carbonyl Metallo Immunoassay
Published in Chembiochem : a European journal of chemical biology (02-04-2004)“…We report the preparation of metal-carbonyl-dendrimer-antibody conjugates. These metal-carbonyl-multilabeled antibodies are designed to be used in a new…”
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Immobilization of atrazine on gold, a first step towards the elaboration of an indirect immunosensor: characterization by XPS and PM-IRRAS
Published in Surface and interface analysis (01-09-2006)“…As part of our long‐term goal to design a novel type of immunosensor based on IR transduction, we devised two strategies to immobilize derivatives of the…”
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Self-Assembling of Redox-Active Atrazine Poly(ethylenimine) Conjugates - Interfacial Electrochemical and Spectroscopic Characterization
Published in Electroanalysis (New York, N.Y.) (01-04-2006)“…Thin films of polymers tethered with both atrazine haptens and ferrocenyl (Fc) probes were formed on polycrystalline gold electrodes by taking advantage of the…”
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Cover Feature: A Solvent‐free, Catalyst‐free Formal [3+3] Cycloaddition Dearomatization Strategy: Towards New Fluorophores for Biomolecules Labelling (ChemSusChem 8/2021)
Published in ChemSusChem (22-04-2021)“…The Cover Feature shows how the Nature‐derived methylcoumalate reacts with N‐aromatics to provide fluorescent molecules helpful for bioimaging. More…”
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conserved acidic motif in the N-terminal domain of nitrate reductase is necessary for the inactivation of the enzyme in the dark by phosphorylation and 14-3-3 binding
Published in Plant physiology (Bethesda) (1999)“…It has previously been shown that the N-terminal domain of tobacco (Nicotiana tabacum) nitrate reductase (NR) is involved in the inactivation of the enzyme by…”
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First carbonyl metallo immunoassay in the environmental area: application to the herbicide chlortoluron
Published in Applied organometallic chemistry (01-11-2002)“…We report a new, non‐isotopic, immunoassay (CMIA) for chlortoluron, a pesticide of the phenylurea family. The novel feature of this assay is the use of metal…”
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A new bioorthogonal cross-linker with alkyne and hydrazide end groups for chemoselective ligation. Application to antibody labelling
Published in Tetrahedron (25-11-2012)“…We describe here the synthesis of the first bioorthogonal cross-linking reagent based on aminocaproic acid core with a hydrazide function at one end to react…”
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Fabrication of multifunctional magnetic nanoparticles bearing metallocarbonyl probes and antibodies
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (05-09-2014)“…The metallocarbonyl-labeled magnetic nanoparticles were derivatized with rabbit IgG to provide IR reporter immunoprobes. •Synthesis and characterization of…”
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Atrazine-Based Self-Assembled Monolayers and Their Interaction with Anti-Atrazine Antibody: Building of an Immunosensor
Published in Langmuir (31-12-2013)“…As a part of our objective to build an immunosensor for the detection of the pesticide atrazine (ATZ) in environmental samples, we studied the self-assembling…”
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Site-specific conjugation of metal carbonyl dendrimer to antibody and its use as detection reagent in immunoassay
Published in Analytical biochemistry (15-12-2010)“…We describe here the conjugation of polyclonal goat anti-rabbit antibody to generation 4 polyamidoamine (G4–PAMAM) dendrimers carrying (i) (η…”
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Infrared optical immunosensor: Application to the measurement of the herbicide atrazine
Published in Analytical biochemistry (01-02-2008)“…A new approach to optically transduce antigen–antibody association, needing no label, is described herein, taking advantage of the ability of…”
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The effect of marine bioactive substances (N PRO) and exogenous cytokinins on nitrate reductase activity in Arabidopsis thaliana
Published in Physiologia plantarum (01-12-2003)“…We investigated the effect of exogenous cytokinins and marine bioactive substances containing seaweed extracts (marketed by the ROULLIER Group under the trade…”
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Preparation and characterization of poly(amidoamine) dendrimers functionalized with a rhenium carbonyl complex and PEG as new IR probes for carbonyl metallo immunoassay
Published in Journal of organometallic chemistry (06-12-2004)“…The first poly(amidoamine) (PAMAM) dendrimers tethered with both (η 5-cyclopentadienyl) rhenium tricarbonyl (CpRe(CO) 3)units and polyethylene glycol (PEG)…”
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Purified polyclonal anti-phenylurea antibodies for an improved immunoaffinity chromatography
Published in Food and agricultural immunology (01-09-1998)“…A one-step technique for the purification of isoproturon antibody has been developed to overcome the common elution problems encountered when high-affinity…”
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