Search Results - "Durand, Ellen M"

A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish by Ablain, Julien, Durand, Ellen M., Yang, Song, Zhou, Yi, Zon, Leonard I.

“…CRISPR/Cas9 technology of genome editing has greatly facilitated the targeted inactivation of genes in vitro and in vivo in a wide range of organisms. In…”
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Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche by Tamplin, Owen J., Durand, Ellen M., Carr, Logan A., Childs, Sarah J., Hagedorn, Elliott J., Li, Pulin, Yzaguirre, Amanda D., Speck, Nancy A., Zon, Leonard I.

“…Hematopoietic stem and progenitor cells (HSPCs) can reconstitute and sustain the entire blood system. We generated a highly specific transgenic reporter of…”
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Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration by Trompouki, Eirini, Bowman, Teresa V., Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S., Cech, Jennifer N., Sessa, Anna K., Leblanc, Jocelyn L., Li, Pulin, Durand, Ellen M., Mosimann, Christian, Heffner, Garrett C., Daley, George Q., Paulson, Robert F., Young, Richard A., Zon, Leonard I.

“…BMP and Wnt signaling pathways control essential cellular responses through activation of the transcription factors SMAD (BMP) and TCF (Wnt). Here, we show…”
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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence by Jing, Lili, Tamplin, Owen J, Chen, Michael J, Deng, Qing, Patterson, Shenia, Kim, Peter G, Durand, Ellen M, McNeil, Ashley, Green, Julie M, Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K, Schlaeger, Thorsten M, Huttenlocher, Anna, Daley, George Q, Ravid, Katya, Zon, Leonard I

“…Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate…”
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Getting more for your marrow: Boosting hematopoietic stem cell numbers with PGE2 by Hagedorn, Elliott J., Durand, Ellen M., Fast, Eva M., Zon, Leonard I.

“…Throughout the lifetime of an individual, hematopoietic stem cells (HSCs) self-renew and differentiate into lineages that include erythrocytes, platelets and…”
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CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation by Hsu, Jingmei, Huang, Hsuan-Ting, Lee, Chung-Tsai, Choudhuri, Avik, Wilson, Nicola K., Abraham, Brian J., Moignard, Victoria, Kucinski, Iwo, Yu, Shuqian, Hyde, R. Katherine, Tober, Joanna, Cai, Xiongwei, Li, Yan, Guo, Yalin, Yang, Song, Superdock, Michael, Trompouki, Eirini, Calero-Nieto, Fernando J., Ghamari, Alireza, Jiang, Jing, Gao, Peng, Gao, Long, Nguyen, Vy, Robertson, Anne L., Durand, Ellen M., Kathrein, Katie L., Aifantis, Iannis, Gerber, Scott A., Tong, Wei, Tan, Kai, Cantor, Alan B., Zhou, Yi, Liu, P. Paul, Young, Richard A., Göttgens, Berthold, Speck, Nancy A., Zon, Leonard I.

“…Hematopoietic stem and progenitor cell (HSPC) formation and lineage differentiation involve gene expression programs orchestrated by transcription factors and…”
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Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment by Durand, Ellen M, Zon, Leonard I

“…PURPOSE OF REVIEWHematopoietic stem cell (HSC) transplantation is an effective treatment for leukemia, lymphoma, blood disorders, and autoimmune diseases…”
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Sorting zebrafish thrombocyte lineage cells with a Cd41 monoclonal antibody enriches hematopoietic stem cell activity by Gansner, John M., Leung, Alexander D., Superdock, Michael, Blair, Megan C., Ammerman, Michelle B., Durand, Ellen M., Barut, Bruce, Handin, Robert I., Stachura, David L., Lu, Chafen, Springer, Timothy A., Zon, Leonard I.

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Stem cells The blood balance by Durand, Ellen M, Zon, Leonard I

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Mechanisms for improving diabetes patient-provider communication through optimal use of e-clinical technologies by Khurana, Laura, Durand, Ellen M, Gary, Sarah Tressel, Otero, Antonio V, Dumais, Kelly M, Beck, Jamie, Zurakowski, David, Hall, Christine Teel, Dallabrida, Susan M

“…Effective health care and patient adherence to their prescribed regimens relies on successful communication between patients and their providers. This study…”
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The blood balance by Durand, Ellen M., Zon, Leonard I.

“…Blood cells are generated from haematopoietic stem cells on demand. The protein Lkb1, which lies at the crossroad of energy metabolism and cell growth, seems…”
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Subjects with osteoarthritis can easily use a handheld touch screen electronic device to report medication use: qualitative results from a usability study by Khurana, Laura, Durand, Ellen M, Gary, Sarah T, Otero, Antonio V, Gerzon, Millie C, Beck, Jamie, Hall, Chris, Dallabrida, Susan M

“…Electronic data capture is increasingly used to improve collection of patient-reported outcome measures in clinical trials and care. The validation of…”
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Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy by Dallabrida, Susan M, Ismail, Nesreen S, Pravda, Elke A, Parodi, Emily M, Dickie, Renee, Durand, Ellen M, Lai, Jean, Cassiola, Flavia, Rogers, Rick A, Rupnick, Maria A

“…Angiopoietins were thought to be endothelial cell-specific via the tie2 receptor. We showed that angiopoietin-1 (ang1) also interacts with integrins on cardiac…”
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The blood balance: blood cells are generated from haematopoietic stem cells on demand. The protein Lkbl, which lies at the crossroad of energy metabolism and cell growth, seems to regulate these stem cells' dynamics by Durand, Ellen M, Zon, Leonard I

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High Resolution Imaging Reveals Hematopoietic Stem Cells in the Perivascular Niche Are Anchored to Mesenchymal Stromal Cells That Orient Their Divisions by Tamplin, Owen J., Durand, Ellen M., Carr, Logan A., Childs, Sarah J., Hagedorn, Elliott H., Zon, Leonard I.

“…Hematopoietic stem cells (HSC) reside in a highly structured microenvironment called the niche. There is two-way communication between a stem cell and its…”
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Hematopoietic Stem Cell Niche Interactions In The Embryo Can Modulate The Size Of The Stem Cell Pool Into Adulthood by Tamplin, Owen J., Durand, Ellen M., Carr, Logan A., Li, Pulin, Zon, Leonard I.

“…Hematopoietic stem cells (HSC) reside in the bone marrow niche and sustain the production of blood throughout life. The entire pool of these rare and important…”
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A Short Pulse of Prostaglandin E2 (PGE2) Induces Long Term Chromatin Changes in Hematopoietic Stem Cells Leading to Increased Self-Renewal and Engraftment by Fast, Eva M, Durand, Ellen M, Sporrij, Audrey, Ojeaburu, Leslie, Maher, Rebecca, Binder, Vera, Yang, Song, Zhou, Yi, Zon, Leonard I.

“…▪ Hematopoietic stem cells (HSCs) offer promising treatment options for many blood diseases. We have previously identified Prostaglandin E2 (PGE2), a small…”
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Stem Cell Arrival in Sites of Hematopoiesis Triggers Supportive Endothelial Niche Formation by Tamplin, Owen J., Durand, Ellen M., Lawson, Katy L., Zon, Leonard I.

“…Abstract 218 Hematopoietic stem and progenitor cells (HSPCs) self-renew and give rise to all blood cell types throughout adulthood. In mammals, definitive…”
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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence by Jing, Lili, Tamplin, Owen J., Chen, Michael J., Deng, Qing, Patterson, Shenia, Kim, Peter Geon, Durand, Ellen M., McNeil, Ashley, Green, Julie M., Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K., Schlaeger, Thorsten M., Huttenlocher, Anna, Daley, George Q., Ravid, Katya, Zon, Leonard I.

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