Search Results - "Duran‐Aniotz, Claudia"

Endoplasmic reticulum proteostasis impairment in aging by Martínez, Gabriela, Duran‐Aniotz, Claudia, Cabral‐Miranda, Felipe, Vivar, Juan P., Hetz, Claudio

“…Summary Perturbed neuronal proteostasis is a salient feature shared by both aging and protein misfolding disorders. The proteostasis network controls the…”
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Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging by Cabral‐Miranda, Felipe, Tamburini, Giovanni, Martinez, Gabriela, Ardiles, Alvaro O, Medinas, Danilo B, Gerakis, Yannis, Hung, Mei‐Li Diaz, Vidal, René, Fuentealba, Matias, Miedema, Tim, Duran‐Aniotz, Claudia, Diaz, Javier, Ibaceta‐Gonzalez, Cristobal, Sabusap, Carleen M, Bermedo‐Garcia, Francisca, Mujica, Paula, Adamson, Stuart, Vitangcol, Kaitlyn, Huerta, Hernan, Zhang, Xu, Nakamura, Tomohiro, Sardi, Sergio Pablo, Lipton, Stuart A, Kennedy, Brian K, Henriquez, Juan Pablo, Cárdenas, J Cesar, Plate, Lars, Palacios, Adrian G, Hetz, Claudio

“…Aging is a major risk factor to develop neurodegenerative diseases and is associated with decreased buffering capacity of the proteostasis network. We…”
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Promoting diversity and overcoming publication barriers in Latin American neuroscience and Alzheimer's disease research: A call to action by Lourenco, Mychael V., Borelli, Wyllians Vendramini, Duran‐Aniotz, Claudia, Zimmer, Eduardo R., Castro, Shamyr Sulyvan

“…Alzheimer's disease (AD) is a global health issue. Because AD is a condition demanding effective management, its socioeconomic burden is immense and threatens…”
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A predictive coding framework of allostatic–interoceptive overload in frontotemporal dementia by Migeot, Joaquin A., Duran-Aniotz, Claudia A., Signorelli, Camilo M., Piguet, Olivier, Ibáñez, Agustín

“…Recent allostatic–interoceptive explanations using predictive coding models propose that efficient regulation of the body’s internal milieu is necessary to…”
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The Latin American Brain Health Institute, a regional initiative to reduce the scale and impact of dementia by Duran‐Aniotz, Claudia, Sanhueza, Jorge, Grinberg, Lea T., Slachevsky, Andrea, Valcour, Victor, Robertson, Ian, Lawlor, Brian, Miller, Bruce, Ibáñez, Agustín

“…Latin American and Caribbean countries face complex challenges to improve brain health and reduce the impact of dementia. Regional hubs devoted to research,…”
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Protein misfolding cyclic amplification of infectious prions by Morales, Rodrigo, Duran-Aniotz, Claudia, Diaz-Espinoza, Rodrigo, Camacho, Manuel V, Soto, Claudio

“…Prions are proteinaceous infectious agents responsible for the transmission of prion diseases. The lack of a procedure for cultivating prions in the laboratory…”
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Latin American women in dementia research: outstanding contributions, barriers, and opportunities from Argentinian, Chilean, and Colombian colleagues by Fittipaldi, Sol, Baez, Sandra, Gonzalez-Silva, Carolina, Duran-Aniotz, Claudia

“…Women's contributions to science have been consistently underrepresented throughout history. Despite many efforts and some progresses being made to reduce…”
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The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science by Ibanez, Agustin, Yokoyama, Jennifer S, Possin, Katherine L, Matallana, Diana, Lopera, Francisco, Nitrini, Ricardo, Takada, Leonel T, Custodio, Nilton, Sosa Ortiz, Ana Luisa, Avila-Funes, José Alberto, Behrens, Maria Isabel, Slachevsky, Andrea, Myers, Richard M, Cochran, J Nicholas, Brusco, Luis Ignacio, Bruno, Martin A, Brucki, Sonia M D, Pina-Escudero, Stefanie Danielle, Okada de Oliveira, Maira, Donnelly Kehoe, Patricio, Garcia, Adolfo M, Cardona, Juan Felipe, Santamaria-Garcia, Hernando, Moguilner, Sebastian, Duran-Aniotz, Claudia, Tagliazucchi, Enzo, Maito, Marcelo, Longoria Ibarrola, Erika Mariana, Pintado-Caipa, Maritza, Godoy, Maria Eugenia, Bakman, Vera, Javandel, Shireen, Kosik, Kenneth S, Valcour, Victor, Miller, Bruce L

“…Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places…”
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Multiscale entropy analysis of retinal signals reveals reduced complexity in a mouse model of Alzheimer’s disease by Araya-Arriagada, Joaquín, Garay, Sebastián, Rojas, Cristóbal, Duran-Aniotz, Claudia, Palacios, Adrián G., Chacón, Max, Medina, Leonel E.

“…Alzheimer’s disease (AD) is one of the most significant health challenges of our time, affecting a growing number of the elderly population. In recent years,…”
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Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches by Duran-Aniotz, Claudia, Moreno-Gonzalez, Ines, Medinas, Danilo B, Morales, Rodrigo

“…The authors cover literature involving biochemical and seeding properties of major ALS-linked proteins including superoxide dismutase 1 (SOD1), transactive…”
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Systematic Review: microRNAs as Potential Biomarkers in Mild Cognitive Impairment Diagnosis by Ogonowski, Natalia, Salcidua, Stefanny, Leon, Tomas, Chamorro-Veloso, Nayaret, Valls, Cristian, Avalos, Constanza, Bisquertt, Alejandro, Rentería, Miguel E, Orellana, Paulina, Duran-Aniotz, Claudia

“…The rate of progression from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD) is estimated at >10% per year, reaching up to 80-90% after 6 years…”
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Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to Alzheimer's disease by Blanco, Kevin, Salcidua, Stefanny, Orellana, Paulina, Sauma-Pérez, Tania, León, Tomás, Steinmetz, Lorena Cecilia López, Ibañez, Agustín, Duran-Aniotz, Claudia, de la Cruz, Rolando

“…Mild cognitive impairment (MCI) is often considered an early stage of dementia, with estimated rates of progression to dementia up to 80-90% after…”
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Risk factors for loneliness in family caregivers of people with dementia and enduring mental health conditions during the COVID‐19 pandemic in Latin America by Leon, Tomas, Miranda‐Castillo, Claudia, Slachevsky, Andrea, Tapia‐Muñoz, Thamara, Olavarria, Loreto, Castro, Loreto, Pinto, Alejandra, Chen, Yaohua Sophie, Leroi, Iracema, Lawlor, Brian, Duran‐Aniotz, Claudia, Grycuk, Emilia, Beber, Bárbara Costa, Peres, Fernando Aguzzoli, Nubia, Carla, Gaitan, Pablo, Vilar‐Compte, Mireya, O'Sullivan, Roger

“…Background During the COVID‐19 pandemic, loneliness has increased in the general population due to government measures to contain the spread of the disease. In…”
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Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability by Duran-Aniotz, Claudia, Moreno-Gonzalez, Ines, Gamez, Nazaret, Perez-Urrutia, Nelson, Vegas-Gomez, Laura, Soto, Claudio, Morales, Rodrigo

“…Amyloid-β (Aβ) misfolding is one of the hallmark pathological features of Alzheimer's disease (AD). AD can manifest with diverse symptomatology including…”
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Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease by Duran-Aniotz, Claudia, Morales, Rodrigo, Moreno-Gonzalez, Ines, Hu, Ping Ping, Fedynyshyn, Joseph, Soto, Claudio

“…Recent studies in animal models of Alzheimer's disease (AD) show that amyloid-beta (Aβ) misfolding can be transmissible; however, the mechanisms by which this…”
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Aged Cattle Brain Displays Alzheimer's Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model by Moreno-Gonzalez, Ines, Edwards, 3rd, George, Morales, Rodrigo, Duran-Aniotz, Claudia, Escobedo, Jr, Gabriel, Marquez, Mercedes, Pumarola, Marti, Soto, Claudio

“…Alzheimer's disease (AD) is one of the leading causes of dementia in late life. Although the cause of AD neurodegenerative changes is not fully understood,…”
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ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related disorders by Torres, Mauricio, Matamala, José Manuel, Duran-Aniotz, Claudia, Cornejo, Victor Hugo, Foley, Andrew, Hetz, Claudio

“…•Prion-like propagation mechanisms in animal models of Alzheimer's disease.•Alteration of the secretory pathway and UPR activation by amyloids.•Description of…”
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DEF8 and Autophagy-Associated Genes Are Altered in Mild Cognitive Impairment, Probable Alzheimer's Disease Patients, and a Transgenic Model of the Disease by Leyton, Esteban, Matus, Diego, Espinoza, Sandra, Benitez, José Matías, Cortés, Bastián I, Gomez, Wileidy, Arévalo, Nohela B, Murgas, Paola, Manque, Patricio, Woehlbier, Ute, Duran-Aniotz, Claudia, Hetz, Claudio, Behrens, María Isabel, SanMartín, Carol D, Nassif, Melissa

“…Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer's disease (AD). However, few studies are available concerning…”
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Infusion of blood from mice displaying cerebral amyloidosis accelerates amyloid pathology in animal models of Alzheimer's disease by Morales, Rodrigo, Duran-Aniotz, Claudia, Bravo-Alegria, Javiera, Estrada, Lisbell D, Shahnawaz, Mohammad, Hu, Ping-Ping, Kramm, Carlos, Morales-Scheihing, Diego, Urayama, Akihiko, Soto, Claudio

“…Previous studies showed that injection of tissue extracts containing amyloid-β (Aβ) aggregates accelerate amyloid deposition in the brain of mouse models of…”
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Associations of body mass index and sarcopenia with screen-detected mild cognitive impairment in older adults in Colombia by O’Donovan, Gary, Sarmiento, Olga L., Hessel, Philipp, Muniz-Terrera, Graciela, Duran-Aniotz, Claudia, Ibáñez, Agustín

“…Background and objective More research is required to understand associations of body mass index (BMI) and sarcopenia with cognition, especially in Latin…”
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