Search Results - "Duran, Tibo"

Where Might Artificial Intelligence Be Going in Pharmaceutical Development? by Duran, Tibo, Chaudhuri, Bodhisattwa

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On the Applicability of the Coarse Grained Coupled CFD-DEM Model to Predict the Heat Transfer During the Fluidized Bed Drying of Pharmaceutical Granules by Aziz, Hossain, Sansare, Sameera, Duran, Tibo, Gao, Yijie, Chaudhuri, Bodhisattwa

“…Fluidized bed dryer often used in the pharmaceutical industry for drying of wet granules. Coupled computational fluid dynamics (CFD) – discrete element method…”
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Molecular Dynamics Modeling Based Investigation of the Effect of Freezing Rate on Lysozyme Stability by Duran, Tibo, Minatovicz, Bruna, Bellucci, Ryan, Bai, Jun, Chaudhuri, Bodhisattwa

“…Purpose The stability of protein drug products frozen during fill finish operations is greatly affected by the freezing rate applied. Non-optimal freezing…”
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CHARMM-GUI Synthetic Polymer Modeler for Modeling and Simulation of Synthetic Polymers by Kyo Choi, Yeol, Duran, Tibo, Im, Wonpil

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Studying the ssDNA loaded adeno-associated virus aggregation using coarse-grained molecular dynamics simulations by Duran, Tibo, Naik, Shivangi, Sharifi, Leila, DiLuzio, Willow R., Chanda, Arani, Chaudhuri, Bodhisattwa

“…Measurement of the center of mass (COM) distance between two empty capsids at 300 K (green line), two full capsids at 300 K (blue line), two empty capsids at…”
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Mitigation of Tribocharging in Pharmaceutical Powders using Surface Modified V-Blenders by Mehta, Tanu, Mukherjee, Raj, Shah, Ami, Mastriani, Trey, Duran, Tibo, Chaudhuri, Bodhisattwa

“…Introduction The pharmaceutical industry involves handling of powders on a large scale for manufacturing of solid dosage forms such as tablets and capsules…”
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Artificial neural networks in tandem with molecular descriptors as predictive tools for continuous liposome manufacturing by Sansare, Sameera, Duran, Tibo, Mohammadiarani, Hossein, Goyal, Manish, Yenduri, Gowtham, Costa, Antonio, Xu, Xiaoming, O'Connor, Thomas, Burgess, Diane, Chaudhuri, Bodhisattwa

“…[Display omitted] The current study utilized an artificial neural network (ANN) to generate computational models to achieve process optimization for a…”
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Coarse-Grained Molecular Dynamics Simulations of Paclitaxel-Loaded Polymeric Micelles by Duran, Tibo, Costa, Antonio, Gupta, Anand, Xu, Xiaoming, Zhang, Hailing, Burgess, Diane, Chaudhuri, Bodhisattwa

“…A continuous manufacturing technology based on coaxial turbulent jet in coflow was previously developed to produce paclitaxel-loaded polymeric micelles…”
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Manufacturing process of liposomal Formation: A coarse-grained molecular dynamics simulation by Duran, Tibo, P. Costa, Antonio, Kneski, Jake, Xu, Xiaoming, J. Burgess, Diane, Mohammadiarani, Hossein, Chaudhuri, Bodhisattwa

“…[Display omitted] A method of producing liposomes has been previously developed using a continuous manufacturing technology that involves a co-axial turbulent…”
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Head-to-head comparison of in vitro and in vivo efficacy of pHLIP-conjugated anti-seed gamma peptide nucleic acids by Dhuri, Karishma, Duran, Tibo, Chaudhuri, Bodhisattwa, Slack, Frank J, Vikram, Ajit, Glazer, Peter M, Bahal, Raman

“…Gamma peptide nucleic acids (γPNAs) have recently garnered attention in diverse therapeutic and diagnostic applications. Serine and…”
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Uncovering the Mechanism of Hepatotoxiciy of PFAS Targeting L-FABP Using GCN and Computational Modeling by Jividen, Lucas, Duran, Tibo, Niu, Xi-Zhi, Bai, Jun

“…Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with known toxicity and bioaccumulation issues. Their widespread industrial…”
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Exploring Latent Space for Generating Peptide Analogs Using Protein Language Models by Liang, Po-Yu, Huang, Xueting, Duran, Tibo, Wiemer, Andrew J, Bai, Jun

“…Generating peptides with desired properties is crucial for drug discovery and biotechnology. Traditional sequence-based and structure-based methods often…”
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