Search Results - "Durántez, Maika"
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Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation
Published in The Journal of immunology (1950) (01-10-2015)“…Regulatory T cell (Treg) activity is modulated by a cooperative complex between the transcription factor NFAT and FOXP3, a lineage specification factor for…”
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Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma
Published in Cancers (19-01-2021)“…(1) Background: Despite the indisputable effectiveness of dexamethasone (DEXA) to reduce inflammation in glioblastoma (GBM) patients, its influence on tumour…”
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Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors
Published in Cancer research (Chicago, Ill.) (01-05-2011)“…Low antigen expression and an absence of coimmunostimulatory signals may be partly responsible for the low immunogenicity of many tumors. It may be possible to…”
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Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin
Published in International journal of cancer (01-08-2012)“…Cervical carcinoma is one of the most common cancers in women worldwide. It is well established that chronic infection of the genital tract by various…”
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Usefulness of an immunohistochemical score in advanced pancreatic neuroendocrine tumors treated with CAPTEM or everolimus
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-01-2021)“…Pancreatic neuroendocrine tumors are rare neoplasms for which few predictive and/or prognostic biomarkers have been validated. Our previous work suggested the…”
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The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo
Published in Journal of Immunology (15-01-2007)“…Vaccination strategies based on the in vivo targeting of Ags to dendritic cells (DCs) are needed to improve the induction of specific T cell immunity against…”
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Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses
Published in Vaccine (16-04-2012)“…Highlights ► Anaphylatoxin C5a and the extra domain A (EDA) from fibronectin induce DC maturation. ► Fusion of C5a and EDA to an antigen improve the…”
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A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo
Published in BioMed research international (01-01-2013)“…The development of tools for efficient targeting of antigens to antigen presenting cells is of great importance for vaccine development. We have previously…”
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Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis
Published in Vaccine (18-10-2010)“…Abstract Staphylococcus epidermidis releases a complex of at least four peptides, termed phenol-soluble modulins (PSM), which stimulate macrophages to produce…”
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