Search Results - "Duquette, P H"

Potentiation of acute acetaminophen lethality by selenium and vitamin E deficiency in mice by Peterson, F J, Lindemann, N J, Duquette, P H, Holtzman, J L

“…The effects of selenium, vitamin E, and DL-methionine deficiency on the acute lethality and hepatotoxicity of acetaminophen in male CD-1 mice were studied…”
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Studies on the N-demethylation and O-de-ethylation of ethylmorphine[6-3H] by male rat hepatic microsomes by Duquette, P H, Holtzman, J L

“…A sensitive and convenient radioassay for the in vitro determination of ethylmorphine N-demethylase and O-de-ethylase activity has been developed…”
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Studies of the metabolic N- and O-demethylation of [6-3H]codeine by Duquette, P H, Peterson, F J, Crankshaw, D L, Lindemann, N J, Holtzman, J L

“…We have modified our radiometric assay for ethylmorphine N-demethylase to examine the metabolism of codeine. We find that the current assay gives excellent…”
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The presence of an inhibitor of ethylmorphine N-demethylase in old ethylmorphine by Duquette, P H, Holtzman, J L

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Role of substrate lipophilicity on the N-demethylation and type I binding of 3-O-alkylmorphine analogs by Duquette, Peter H, Erickson, Richard R, Holtzman, Jordan L

“…A series of 3-O-alkylmorphine analogues was synthesized to determine if there was a good correlation between the rate of metabolism, type I binding affinity,…”
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Ethanol induction of acetaminophen toxicity and metabolism by Peterson, F J, Holloway, D E, Erickson, R R, Duquette, P H, McClain, C J, Holtzman, J L

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Dietary ascorbic acid and hepatic mixed function oxidase activity in the guinea pig by Peterson, F J, Holloway, D E, Duquette, P H, Rivers, J M

“…Studies were carried out to characterize the response of hepatic mixed function oxidase (MFO) activity to chronic ascorbic acid deficiency and excessive…”
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Puromycin analogs. Ribosomal binding and peptidyl transferase substrate activity of a carbocyclic analog of 8-azapuromycin by Duquette, Peter H, Ritter, Clare L, Vince, Robert

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The effect of phenobarbital, 3-methylcholanthrene, and pregnenolone-16 alpha-carbonitrile on the N-demethylation and O-de-ethylation of [6-H3]ethylmorphine by Duquette, P H, Peterson, F J, Erickson, R R, Holtzman, J L

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