Search Results - "Duquette, Natacha"
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Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice
Published in PloS one (24-03-2016)“…Exercise is an effective approach for primary and secondary prevention of cardiovascular diseases (CVD) and loss of muscular mass and function. Its benefits…”
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Nestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)- cells
Published in PloS one (27-04-2017)“…Renal and lung fibrosis was characterized by the accumulation of collagen-immunoreactive mesenchymal cells expressing the intermediate filament protein nestin…”
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The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice
Published in PloS one (19-03-2014)“…To demonstrate that p53 modulates endothelial function and the stress response to a high-fat western diet (WD). Three-month old p53+/+ wild type (WT) and…”
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Lack of Angiopoietin‐Like‐2 Expression Limits the Metabolic Stress Induced by a High‐Fat Diet and Maintains Endothelial Function in Mice
Published in Journal of the American Heart Association (15-08-2014)“…Background Angiopoietin‐like‐2 (angptl2) is produced by several cell types including endothelial cells, adipocytes and macrophages, and contributes to the…”
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Abstract 2910: A novel Sortilin-targeted docetaxel peptide conjugate (TH1902), for the treatment of Sortilin-positive (SORT1+) triple-negative breast cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Rational: Breast cancers are comprised of several subtypes that share similar clinicopathological features, but that also exhibit several different…”
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Knockdown of ANGPTL2 promotes cardiac left ventricular dysfunction in mice via up‐regulation of NOX4
Published in The FASEB journal (01-04-2020)“…Abstract only Introduction Angiopoietin‐like 2 (ANGPTL2) is a pro‐inflammatory and pro‐oxidative glycoprotein that induces vascular endothelial dysfunction in…”
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Knockdown of angiopoietin like-2 protects against angiotensin II-induced cerebral endothelial dysfunction in mice
Published in American journal of physiology. Heart and circulatory physiology (01-03-2015)“…Angiopoietin like-2 (angptl2) is a circulating pro-inflammatory and pro-oxidative protein, but its role in regulating cerebral endothelial function remains…”
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ADCY9 (Adenylate Cyclase Type 9) Inactivation Protects From Atherosclerosis Only in the Absence of CETP (Cholesteryl Ester Transfer Protein)
Published in Circulation (New York, N.Y.) (16-10-2018)“…BACKGROUND:Pharmacogenomic studies have shown that ADCY9 genotype determines the effects of the CETP (cholesteryl ester transfer protein) inhibitor dalcetrapib…”
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Nestin upregulation characterizes vascular remodeling secondary to hypertension in the rat
Published in American journal of physiology. Heart and circulatory physiology (15-05-2015)“…Proliferation and hypertrophy of vascular smooth muscle cells represent hallmark features of vessel remodeling secondary to hypertension. The intermediate…”
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Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow
Published in American journal of physiology. Heart and circulatory physiology (15-03-2012)“…Endothelial dysfunction and oxidative stress contribute to the atherosclerotic process that includes stiffening of large peripheral arteries. In contrast, our…”
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Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice
Published in American journal of physiology. Heart and circulatory physiology (01-11-2011)“…The cardiac cycle imposes a mechanical stress that dilates elastic carotid arteries, while shear stress largely contributes to the endothelium-dependent…”
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Abstract 624: Interactions Between Adenylate Cyclase Type 9 (ADCY9) and Cholesteryl Ester Transfer Protein (CETP) in Atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2018)“…Abstract only Pharmacogenomic studies have shown that ADCY9 genotype determines the effects of the cholesteryl ester transfer protein (CETP) inhibitor…”
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Angiopoietin‐Like 2 Promotes Atherogenesis in Mice
Published in Journal of the American Heart Association (01-06-2013)“…Background Angiopoietin like‐2 (angptl2), a proinflammatory protein, is overexpressed in endothelial cells (ECs) from patients with coronary artery disease…”
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Abstract 16267: NADPH Oxidase Nox4 Up-regulation Contributes to the Worsening of Pressure Overload-induced Cardiac Dysfunction in Angiopoeitin-like 2 Knockdown Mice
Published in Circulation (New York, N.Y.) (10-11-2015)“…BackgroundAngiopoietin-like 2 (angptl2) is a circulating protein promoting vascular inflammation and endothelial dysfunction in mice, but little is known on…”
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Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice
Published in Pflügers Archiv (01-02-2013)“…We aimed to evaluate the lasting functional imprinting of exercise (EX) and catechin (CAT) on the vascular function of middle-age mice switched to a…”
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Voluntary exercise prevents cerebrovascular dysfunction and remodelling associated with atherosclerosis in mice
Published in The FASEB journal (01-04-2011)“…Physical exercise (PEx) has beneficial vascular effects. In mouse cerebral arteries atherosclerosis is associated endothelial dysfunction and changes in the…”
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Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice: e0151526
Published in PloS one (01-03-2016)“…Exercise is an effective approach for primary and secondary prevention of cardiovascular diseases (CVD) and loss of muscular mass and function. Its benefits…”
Get full text
Journal Article -
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The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes
Published in Cardiovascular diabetology (12-08-2013)“…Cardiac nestin(+) cells exhibit properties of a neural progenitor/stem cell population characterized by the de novo synthesis of neurofilament-M in response to…”
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