Search Results - "Dupuis, Julien P"

NMDA receptor functions in health and disease: Old actor, new dimensions by Dupuis, Julien P., Nicole, Olivier, Groc, Laurent

“…N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) play key roles in synaptogenesis, synaptic maturation, long-term plasticity, neuronal network…”
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Surface trafficking of neurotransmitter receptors: From cultured neurons to intact brain preparations by Dupuis, Julien P., Groc, Laurent

“…Over the last decade, developments in single molecule imaging have changed our vision of synaptic physiology. By providing high spatio-temporal resolution maps…”
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Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission by Murphy-Royal, Ciaran, Dupuis, Julien P, Varela, Juan A, Panatier, Aude, Pinson, Benoît, Baufreton, Jérôme, Groc, Laurent, Oliet, Stéphane H R

“…The authors find that glutamate release increases the diffusion of the astrocytic glutamate transporter GLT-1 in the plasma membrane. This activity-dependent…”
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Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients by Jézéquel, Julie, Johansson, Emily M., Dupuis, Julien P., Rogemond, Véronique, Gréa, Hélène, Kellermayer, Blanka, Hamdani, Nora, Le Guen, Emmanuel, Rabu, Corentin, Lepleux, Marilyn, Spatola, Marianna, Mathias, Elodie, Bouchet, Delphine, Ramsey, Amy J., Yolken, Robert H., Tamouza, Ryad, Dalmau, Josep, Honnorat, Jérôme, Leboyer, Marion, Groc, Laurent

“…The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric disorders has fostered new conceptual and clinical frameworks…”
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Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices by Varela, Juan A., Dupuis, Julien P., Etchepare, Laetitia, Espana, Agnès, Cognet, Laurent, Groc, Laurent

“…Single-molecule imaging has changed the way we understand many biological mechanisms, particularly in neurobiology, by shedding light on intricate molecular…”
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Distance-dependent regulation of NMDAR nanoscale organization along hippocampal neuron dendrites by Ferreira, Joana S., Dupuis, Julien P., Kellermayer, Blanka, Bénac, Nathan, Manso, Constance, Bouchet, Delphine, Levet, Florian, Butler, Corey, Sibarita, Jean-Baptiste, Groc, Laurent

“…Hippocampal pyramidal neurons are characterized by a unique arborization subdivided in segregated dendritic domains receiving distinct excitatory synaptic…”
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Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors by Ladepeche, Laurent, Dupuis, Julien P., Bouchet, Delphine, Doudnikoff, Evelyne, Yang, Luting, Campagne, Yohan, Bézard, Erwan, Hosy, Eric, Groc, Laurent

“…Dopamine is a powerful modulator of glutamatergic neurotransmission and NMDA receptor-dependent synaptic plasticity. Although several intracellular cascades…”
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Editorial: NMDA receptors in physiology and disease by Baez, María Verónica, Dupuis, Julien P, Calfa, Gaston Diego

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Multi-Dimensional Spectral Single Molecule Localization Microscopy by Butler, Corey, Saraceno, G Ezequiel, Kechkar, Adel, Bénac, Nathan, Studer, Vincent, Dupuis, Julien P, Groc, Laurent, Galland, Rémi, Sibarita, Jean-Baptiste

“…Single molecule localization (SML) and tracking (SPT) techniques, such as (spt)PALM, (u/DNA)PAINT and quantum dot tracking, have given unprecedented insight…”
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Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain by Godin, Antoine G., Varela, Juan A., Gao, Zhenghong, Danné, Noémie, Dupuis, Julien P., Lounis, Brahim, Groc, Laurent, Cognet, Laurent

“…A super-resolution imaging technique based on single-nanotube tracking is used to study the nanoscale organization and local viscosity of the brain…”
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Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the KATP channel subunits SUR2A and Kir6.2 by Dupuis, Julien P., Revilloud, Jean, Moreau, Christophe J., Vivaudou, Michel

“…Cardiac ATP-sensitive potassium (K ATP ) channels are metabolic sensors formed by the association of the inward rectifier potassium channel Kir6.2 and the…”
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Impact of Disease-causing SUR1 Mutations on the KATP Channel Subunit Interface Probed with a Rhodamine Protection Assay by Hosy, Eric, Dupuis, Julien P., Vivaudou, Michel

“…The function of the ATP-sensitive potassium (KATP) channel relies on the proper coupling between its two subunits: the pore-forming Kir6.2 and the regulator…”
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Ketamine alleviates NMDA receptor hypofunction through synaptic trapping by Villéga, Frédéric, Fernandes, Alexandra, Jézéquel, Julie, Uyttersprot, Floriane, Benac, Nathan, Zenagui, Sarra, Bastardo, Laurine, Gréa, Hélène, Bouchet, Delphine, Villetelle, Léa, Nicole, Olivier, Rogemond, Véronique, Honnorat, Jérôme, Dupuis, Julien P, Groc, Laurent

“…Activity-dependent modulations of N-methyl-D-aspartate glutamate receptor (NMDAR) trapping at synapses regulate excitatory neurotransmission and shape…”
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Tracking single membrane targets of human autoantibodies using single nanoparticle imaging by Jézéquel, Julie, Dupuis, Julien P., Maingret, François, Groc, Laurent

“…•An increasing number of neuropsychiatric diseases have been associated with the expression of human autoantibodies directed against neuronal…”
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Surface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapses by Dupuis, Julien P, Ladépêche, Laurent, Seth, Henrik, Bard, Lucie, Varela, Juan, Mikasova, Lenka, Bouchet, Delphine, Rogemond, Véronique, Honnorat, Jérôme, Hanse, Eric, Groc, Laurent

“…NMDA‐type glutamate receptors (NMDAR) are central actors in the plasticity of excitatory synapses. During adaptive processes, the number and composition of…”
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Dynamics of surface neurotransmitter receptors and transporters in glial cells: Single molecule insights by Ciappelloni, Silvia, Murphy-Royal, Ciaran, Dupuis, Julien P., Oliet, Stéphane H.R., Groc, Laurent

“…[Display omitted] •Principle of single nanoparticle tracking on live glial cells.•Single molecule imaging revealed high surface dynamics of proteins onto…”
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Coupling ion channels to receptors for biomolecule sensing by Moreau, Christophe J, Vivaudou, Michel, Dupuis, Julien P, Revilloud, Jean, Arumugam, Karthik

“…Nanoscale electrical biosensors are promising tools for diagnostics and high-throughput screening systems. The electrical signal allows label-free assays with…”
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Long-term depression at distinct glutamatergic synapses in the basal ganglia by Dupuis, Julien P, Bioulac, Bernard H, Baufreton, Jérôme

“…Long-term adaptations of synaptic transmission are believed to be the cellular basis of information storage in the brain. In particular, long-term depression…”
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Tuning the allosteric regulation of artificial muscarinic and dopaminergic ligand-gated potassium channels by protein engineering of G protein-coupled receptors by Moreau, Christophe J., Revilloud, Jean, Caro, Lydia N., Dupuis, Julien P., Trouchet, Amandine, Estrada-Mondragón, Argel, Nieścierowicz, Katarzyna, Sapay, Nicolas, Crouzy, Serge, Vivaudou, Michel

“…Ligand-gated ion channels enable intercellular transmission of action potential through synapses by transducing biochemical messengers into electrical signal…”
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Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the K(ATP) channel subunits SUR2A and Kir6.2 by Dupuis, Julien P, Revilloud, Jean, Moreau, Christophe J, Vivaudou, Michel

“…Cardiac ATP-sensitive potassium (K(ATP)) channels are metabolic sensors formed by the association of the inward rectifier potassium channel Kir6.2 and the…”
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