Search Results - "Dupree, J. L."

Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner by Benusa, S D, George, N M, Sword, B A, DeVries, G H, Dupree, J L

“…Chronic microglia-mediated inflammation and oxidative stress are well-characterized underlying factors in neurodegenerative disease, whereby reactive…”
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Sulfatide is essential for the maintenance of CNS myelin and axon structure by Marcus, J., Honigbaum, S., Shroff, S., Honke, K., Rosenbluth, J., Dupree, J.L.

“…Galactocerebroside (GalC) and sulfatide are abundant myelin lipids. In mice incapable of synthesizing these lipids, myelin is thin and regionally unstable and…”
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Adult‐onset depletion of sulfatide leads to axonal degeneration with relative myelin sparing by Dustin, E., McQuiston, A. R., Honke, K., Palavicini, J. P., Han, X., Dupree, J. L.

“…3‐O‐sulfogalactosylceramide (sulfatide) constitutes a class of sphingolipids that comprise about 4% of myelin lipids in the central nervous system. Previously,…”
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Nfasc155H and MAG are Specifically Susceptible to Detergent Extraction in the Absence of the Myelin Sphingolipid Sulfatide by Pomicter, A. D., DeLoyht, J. M., Hackett, A. R., Purdie, N., Sato-Bigbee, C., Henderson, S. C., Dupree, J. L.

“…Mice incapable of synthesizing the myelin lipid sulfatide form paranodes that deteriorate with age. Similar instability also occurs in mice that lack…”
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Effects of galactolipid elimination on oligodendrocyte development and myelination by Marcus, Jill, Dupree, Jeffrey L., Popko, Brian

“…The galactolipids galactocerebroside and sulfatide, which require the enzyme UDP‐galactose:ceramide galactosyltransferase (CGT) for their synthesis, are among…”
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Demyelination and altered expression of myelin-associated glycoprotein isoforms in the central nervous system of galactolipid-deficient mice by Coetzee, Timothy, Dupree, Jeffrey L., Popko, Brian

“…Vertebrate myelin is enriched in the lipid galactocerebroside (GalC) and its sulfated derivated sulfatide. To understand the in vivo function of these lipids,…”
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Retardation of neuritic outgrowth and cytoskeletal changes accompany acetylcholinesterase inhibitor treatment in cultured rat dorsal root ganglion neurons by Dupree, J L, Bigbee, J W

“…Over the past two decades acetylcholinesterase (AChE) has been shown to be present in numerous non-cholinergic and non-cholinoceptive tissues. Interestingly,…”
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Adult CST-null mice maintain an increased number of oligodendrocytes by Shroff, S.M., Pomicter, A.D., Chow, W.N., Fox, M.A., Colello, R.J., Henderson, S.C., Dupree, J.L.

“…The galactolipids galactocerebroside and sulfatide have been implicated in oligodendrocyte (OL) development and myelin formation. Much of the early evidence…”
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A Myelin Galactolipid, Sulfatide, Is Essential for Maintenance of Ion Channels on Myelinated Axon But Not Essential for Initial Cluster Formation by Ishibashi, Tomoko, Dupree, Jeffrey L, Ikenaka, Kazuhiro, Hirahara, Yukie, Honke, Koichi, Peles, Elior, Popko, Brian, Suzuki, Kinuko, Nishino, Hitoo, Baba, Hiroko

“…Myelinated axons are divided into four distinct regions: the node of Ranvier, paranode, juxtaparanode, and internode, each of which is characterized by a…”
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Axo-Glial Interactions Regulate the Localization of Axonal Paranodal Proteins by Dupree, Jeffrey L., Girault, Jean-Antoine, Popko, Brian

“…Mice incapable of synthesizing the abundant galactolipids of myelin exhibit disrupted paranodal axo-glial interactions in the central and peripheral nervous…”
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Myelin-Associated Glycoprotein and Myelin Galactolipids Stabilize Developing Axo-Glial Interactions by Marcus, Jill, Dupree, Jeffrey L., Popko, Brian

“…We have analyzed mice that lack both the myelin-associated glycoprotein (MAG) and the myelin galactolipids, two glial components implicated in mediating…”
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The Neuronal Adhesion Protein TAG-1 Is Expressed by Schwann Cells and Oligodendrocytes and Is Localized to the Juxtaparanodal Region of Myelinated Fibers by Traka, Maria, Dupree, Jeffrey L, Popko, Brian, Karagogeos, Domna

“…The neural cell adhesion molecule TAG-1, which is a glycosylphosphatidylinositol-linked member of the Ig superfamily, is expressed by various neuronal…”
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Inverse correlation of acetylcholinesterase (AChE) activity with the presence of neurofilament inclusions in dorsal root ganglion neurons cultured in the presence of a reversible inhibitor of AChE by Dupree, J.L., Maynor, E.N., Bigbee, J.W.

“…We have previously shown that treatment of cultured dorsal root ganglion neurons (DRGN) with a highly specific, reversible acetylcholinesterase (AChE)…”
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Myelin Galactolipids Are Essential for Proper Node of Ranvier Formation in the CNS by Dupree, Jeffrey L, Coetzee, Timothy, Blight, Andrew, Suzuki, Kinuko, Popko, Brian

“…The vertebrate myelin sheath is greatly enriched in the galactolipids galactocerebroside (GalC) and sulfatide. Mice with a disruption in the gene that encodes…”
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Nodal sodium channel domain integrity depends on the conformation of the paranodal junction, not on the presence of transverse bands by Rosenbluth, Jack, Dupree, Jeffrey L., Popko, Brian

“…Our understanding of the role that axoglial interactions play in node of Ranvier formation and maintenance remains incomplete. Previous studies of CNS…”
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Galactolipids in the formation and function of the myelin sheath by Dupree, Jeffrey L., Suzuki, Kinuko, Popko, Brian

“…Among the most abundant components of myelin are the galactolipids galactocerebroside (GalC) and sulfatide. In spite of this abundance, the roles that these…”
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CaMKII  Regulates Oligodendrocyte Maturation and CNS Myelination by Waggener, C. T., Dupree, J. L., Elgersma, Y., Fuss, B.

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Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS by Domènech-Estévez, Enric, Baloui, Hasna, Meng, Xiaosong, Zhang, Yanqing, Deinhardt, Katrin, Dupree, Jeff L, Einheber, Steven, Chrast, Roman, Salzer, James L

“…The signaling pathways that regulate myelination in the PNS remain poorly understood. Phosphatidylinositol-4,5-bisphosphate 3-kinase 1A, activated in Schwann…”
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Interferon-γ inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress by Lin, Wensheng, Kemper, April, Dupree, Jeffrey L., Harding, Heather P., Ron, David, Popko, Brian

“…Interferon-γ (IFN-γ) is believed to play a deleterious role in the immune-mediated demyelinating disorder multiple sclerosis. Here we have exploited transgenic…”
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Seasonal localization of a collagenous protein in the organic matrix of spicules from the gorgonian Leptogorgia virgulata (Cnidaria: Gorgonacea) by KINGSLEY, R. J, DUPREE, J. L

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