Search Results - "Dupont, Christopher D."

Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1 by Hirahara, Kiyoshi, Ghoreschi, Kamran, Yang, Xiang-Ping, Takahashi, Hayato, Laurence, Arian, Vahedi, Golnaz, Sciumè, Giuseppe, Hall, Aisling O'Hara, Dupont, Christopher D., Francisco, Loise M., Chen, Qian, Tanaka, Masao, Kanno, Yuka, Sun, Hong-Wei, Sharpe, Arlene H., Hunter, Christopher A., O'Shea, John J.

“…Interleukin-27 (IL-27) is a key immunosuppressive cytokine that counters T helper 17 (Th17) cell-mediated pathology. To identify mechanisms by which IL-27…”
Get full text

Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii by Dupont, Christopher D, Christian, David A, Selleck, Elizabeth M, Pepper, Marion, Leney-Greene, Michael, Harms Pritchard, Gretchen, Koshy, Anita A, Wagage, Sagie, Reuter, Morgan A, Sibley, L David, Betts, Michael R, Hunter, Christopher A

“…During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to CD4+ and CD8+ T cells is essential for…”
Get full text

Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires by Jia, Bin, McNeil, Lisa K, Dupont, Christopher D, Tsioris, Konstantinos, Barry, Rachel M, Scully, Ingrid L, Ogunniyi, Adebola O, Gonzalez, Christopher, Pride, Michael W, Gierahn, Todd M, Liberator, Paul A, Jansen, Kathrin U, Love, J Christopher

“…The efficacy of protein-conjugated pneumococcal polysaccharide vaccines has been well characterized for children. The level of protection conferred by…”
Get full text

Guanylate-Binding Proteins: Niche Recruiters for Antimicrobial Effectors by Dupont, Christopher D., Hunter, Christopher A.

“…There are fundamental questions regarding how IFN-γ activates host cells to eliminate intracellular pathogens. In this issue of Immunity, Yamamoto et al…”
Get full text

A Host GPCR Signaling Network Required for the Cytolysis of Infected Cells Facilitates Release of Apicomplexan Parasites by Millholland, Melanie G., Mishra, Satish, Dupont, Christopher D., Love, Melissa S., Patel, Bhumit, Shilling, Dustin, Kazanietz, Marcelo G., Foskett, J. Kevin, Hunter, Christopher A., Sinnis, Photini, Greenbaum, Doron C.

“…Following intracellular replication, the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii cause host cell cytolysis to facilitate parasite…”
Get full text

Immune response and immunopathology during toxoplasmosis by Dupont, Christopher D., Christian, David A., Hunter, Christopher A.

“…Toxoplasma gondii is a protozoan parasite of medical and veterinary significance that is able to infect any warm-blooded vertebrate host. In addition to its…”
Get full text

Role of the NF-κB transcription factor c-Rel in the generation of CD8+ T-cell responses to Toxoplasma gondii by Jordan, Kimberly A., Dupont, Christopher D., Tait, Elia D., Liou, Hsiou-Chi, Hunter, Christopher A.

“…The nuclear factor κB transcription factor c-Rel is exclusively expressed in immune cells and plays a role in numerous cellular functions including…”
Get full text

African Trypanosomes Contain 5-Methylcytosine in Nuclear DNA by Militello, Kevin T, Wang, Ping, Jayakar, Sangeeta K, Pietrasik, Rebecca L, Dupont, Christopher D, Dodd, Kristi, King, Anthony M, Valenti, Paul R

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Flt3 Ligand Is Essential for Survival and Protective Immune Responses during Toxoplasmosis by Dupont, Christopher D, Harms Pritchard, Gretchen, Hidano, Shinya, Christian, David A, Wagage, Sagie, Muallem, Gaia, Tait Wojno, Elia D, Hunter, Christopher A

“…Dendritic cells (DCs) are critical for resistance to Toxoplasma gondii, and infection with this pathogen leads to increased numbers of DCs at local sites of…”
Get full text

Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells by Tait, Elia D, Jordan, Kimberly A, Dupont, Christopher D, Harris, Tajie H, Gregg, Beth, Wilson, Emma H, Pepper, Marion, Dzierszinski, Florence, Roos, David S, Hunter, Christopher A

“…The Toxoplasma gondii population consists of multiple strains, defined by genotype and virulence. Previous studies have established that protective immunity to…”
Get full text

Two Vaccines for Staphylococcus aureus Induce a B-Cell-Mediated Immune Response by Dupont, Christopher D, Scully, Ingrid L, Zimnisky, Ross M, Monian, Brinda, Rossitto, Christina P, O'Connell, Ellen B, Jansen, Kathrin U, Anderson, Annaliesa S, Love, J Christopher

“…causes severe disease in humans for which no licensed vaccine exists. A novel vaccine (SA4Ag) is in development, targeting the capsular polysaccharides (CPs)…”
Get full text

Phase I open-label, ascending dose trial of AGEN1884, an anti-CTLA-4 monoclonal antibody, in advanced solid malignancies: Dose selection for combination with PD-1 blockade by Wilky, Breelyn A., Kumthekar, Priya, Wesolowski, Robert, Hwang, Jimmy J., Park, Steven I., Proscurshim, Igor, Yuan, Guojun, Dupont, Christopher D, Shebanova, Olga, Cuillerot, Jean-Marie, Dow, Edward, Raizer, Jeffrey J., Gentry, Carleen, Ross, Ainsley, Drouin, Elise, Wilson, Nicholas, Goldberg, John M., Buell, Jennifer, Stein, Robert Benjamin

“…Abstract only…”
Get full text

Phase 1/2 open-label, multiple ascending dose trial of AGEN2034, an anti-PD-1 monoclonal antibody, in advanced solid malignancies: Results of dose escalation by Moore, Kathleen N., Dresher, Charles, Liu, Joyce, O'Malley, David M., Wang, Edward Wenge, Wang, Judy Sing-Zan, Subbiah, Vivek, Wilky, Breelyn A., Yuan, Guojun, Dupont, Christopher D, Gonzalez, Ana M, Savitsky, David, Coulter, Sara, Shebanova, Olga, Dow, Ed, Proscurshim, Igor, Buell, Jennifer, Stein, Robert Benjamin, Youssoufian, Hagop

“…Abstract only…”
Get full text

Flt3L is essential for survival and protective immune responses during toxoplasmosis by Dupont, Christopher D., Pritchard, Gretchen Harms, Hidano, Shinya, Christian, David A., Wagage, Sagie, Muallem, Gaia, Tait Wojno, Elia D., Hunter, Christopher A.

“…Dendritic cells (DCs) are critical for resistance to Toxoplasma gondii , and infection with this pathogen leads to increased numbers of DCs at local sites of…”
Get full text

Immune response and immunopathology during toxoplasmosis1 by Dupont, Christopher D., Christian, David A., Hunter, Christopher A.

“…Toxoplasma gondii is a protozoan parasite of medical and veterinary significance that is able to infect any warm-blooded vertebrate host. In addition to its…”
Get full text

Immune response and immunopathology during toxoplasmosis: Immunoparasitology by DUPONT, Christopher D, CHRISTIAN, David A, HUNTER, Christopher A

Get full text

Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii: e1004047 by Dupont, Christopher D, Christian, David A, Selleck, Elizabeth M, Pepper, Marion, Leney-Greene, Michael, Pritchard, Gretchen Harms, Koshy, Anita A, Wagage, Sagie, Reuter, Morgan A, Sibley, L David, Betts, Michael R, Hunter, Christopher A

“…During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to CD4+ and CD8+ T cells is essential for…”
Get full text

Parasite fate and involvement of infected cells in the induction of [CD4.sup.+] and [CD8.sup.+] T cell responses to toxoplasma gondii by Dupont, Christopher D, Christian, David A, Selleck, Elizabeth M, Pepper, Marion, Leney-Greene, Michael, Pritchard, Gretchen Harms, Koshy, Anita A, Wagage, Sagie, Reuter, Morgan A, Sibley, L. David, Betts, Michael R, Hunter, Christopher A

“…During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to [CD4.sup.+] and [CD8.sup.+] T cells is…”
Get full text

Two Vaccines for italic toggle="yes">Staphylococcus aureus /italic> Induce a B-Cell-Mediated Immune Response by Christopher D. Dupont, Ingrid L. Scully, Ross M. Zimnisky, Brinda Monian, Christina P. Rossitto, Ellen B. O'Connell, Kathrin U. Jansen, Annaliesa S. Anderson, J. Christopher Love

“…ABSTRACT Staphylococcus aureus causes severe disease in humans for which no licensed vaccine exists. A novel S. aureus vaccine (SA4Ag) is in development,…”
Get full text

Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells1 by Tait, Elia D., Jordan, Kimberly A., Dupont, Christopher D., Harris, Tajie H., Gregg, Beth, Wilson, Emma H., Pepper, Marion, Dzierszinski, Florence, Roos, David S., Hunter, Christopher A.

“…The Toxoplasma gondii population consists of multiple strains, defined by genotype and virulence. Previous studies have established that protective immunity to…”
Get full text