Search Results - "Dupont, Aline"

The intestinal epithelium as guardian of gut barrier integrity by Zhang, Kaiyi, Hornef, Mathias W., Dupont, Aline

“…Summary A single layer of epithelial cells separates the intestinal lumen from the underlying sterile tissue. It is exposed to a multitude of nutrients and a…”
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Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition by Fulde, Marcus, Sommer, Felix, Chassaing, Benoit, van Vorst, Kira, Dupont, Aline, Hensel, Michael, Basic, Marijana, Klopfleisch, Robert, Rosenstiel, Philip, Bleich, André, Bäckhed, Fredrik, Gewirtz, Andrew T., Hornef, Mathias W.

“…Alterations in enteric microbiota are associated with several highly prevalent immune-mediated and metabolic diseases 1 – 3 , and experiments involving faecal…”
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Minimal SPI1-T3SS effector requirement for Salmonella enterocyte invasion and intracellular proliferation in vivo by Zhang, Kaiyi, Riba, Ambre, Nietschke, Monika, Torow, Natalia, Repnik, Urska, Pütz, Andreas, Fulde, Marcus, Dupont, Aline, Hensel, Michael, Hornef, Mathias

“…Effector molecules translocated by the Salmonella pathogenicity island (SPI)1-encoded type 3 secretion system (T3SS) critically contribute to the pathogenesis…”
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P. gingivalis in Periodontal Disease and Atherosclerosis - Scenes of Action for Antimicrobial Peptides and Complement by Hussain, Mehak, Stover, Cordula M, Dupont, Aline

“…According to the NHS, it is estimated that over 50% of the adult population are, to some extent, affected by gum disease and approximately 15% of UK population…”
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Antimicrobial peptides and the enteric mucus layer act in concert to protect the intestinal mucosa by Dupont, Aline, Heinbockel, Lena, Brandenburg, Klaus, Hornef, Mathias W

“…The intestinal mucosa squares the circle by allowing efficient nutrient absorption while generating a firm barrier toward the enteric microbiota,…”
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Age-dependent enterocyte invasion and microcolony formation by Salmonella by Zhang, Kaiyi, Dupont, Aline, Torow, Natalia, Gohde, Frederik, Gohde, Fredrik, Leschner, Sara, Lienenklaus, Stefan, Weiss, Siegfried, Brinkmann, Melanie M, Kühnel, Mark, Hensel, Michael, Fulde, Marcus, Hornef, Mathias W

“…The coordinated action of a variety of virulence factors allows Salmonella enterica to invade epithelial cells and penetrate the mucosal barrier. The influence…”
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Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice by Dupont, Aline, Sommer, Felix, Zhang, Kaiyi, Repnik, Urska, Basic, Marijana, Bleich, André, Kühnel, Mark, Bäckhed, Fredrik, Litvak, Yael, Fulde, Marcus, Rosenshine, Ilan, Hornef, Mathias W

“…Enteropathogenic Escherichia coli (EPEC) represents a major causative agent of infant diarrhea associated with significant morbidity and mortality in…”
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Preclinical Investigations Reveal the Broad-Spectrum Neutralizing Activity of Peptide Pep19-2.5 on Bacterial Pathogenicity Factors by HEINBOCKEL, Lena, SANCHEZ-GOMEZ, Susana, ERNST, Martin, GUTSMANN, Thomas, SCHÜRHOLZ, Tobias, BRANDENBURG, Klaus, MARTINEZ DE TEJADA, Guillermo, DÖMMING, Sabine, BRANDENBURG, Julius, KACONIS, Yani, HORNEF, Mathias, DUPONT, Aline, MARWITZ, Sebastian, GOLDMANN, Torsten

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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MicroRNA‐146a‐mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury by Chassin, Cécilia, Hempel, Cordelia, Stockinger, Silvia, Dupont, Aline, Kübler, Joachim F., Wedemeyer, Jochen, Vandewalle, Alain, Hornef, Mathias W.

“…Intestinal ischemia/reperfusion (I/R) injury causes inflammation and tissue damage and is associated with high morbidity and mortality. Uncontrolled activation…”
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Bacterial cell wall compounds as promising targets of antimicrobial agents I. Antimicrobial peptides and lipopolyamines by Martínez de Tejada, Guillermo, Sánchez-Gómez, Susana, Rázquin-Olazaran, Iosu, Kowalski, Ina, Kaconis, Yani, Heinbockel, Lena, Andrä, Jörg, Schürholz, Tobias, Hornef, Mathias, Dupont, Aline, Garidel, Patrick, Lohner, Karl, Gutsmann, Thomas, David, Sunil A, Brandenburg, Klaus

“…The first barrier that an antimicrobial agent must overcome when interacting with its target is the microbial cell wall. In the case of Gram-negative bacteria,…”
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CONEXÃO URBANA: ESTRATÉGIA DE DESENVOLVIMENTO SUSTENTÁVEL by Lima, Márcia Azevedo de, Dupont, Aline

“…O fortalecimento dos polos urbanos vai ao encontro do desenvolvimento urbano sustentável. Entretanto, a integração entre esses polos pode ser dificultada, por…”
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Bacterial cell wall compounds as promising targets of antimicrobial agents II. Immunological and clinical aspects by Schuerholz, Tobias, Dömming, Sabine, Hornef, Mathias, Dupont, Aline, Kowalski, Ina, Kaconis, Yani, Heinbockel, Lena, Andrä, Jörg, Garidel, Patrick, Gutsmann, Thomas, David, Sunil, Sánchez-Gómez, Susana, Martinez de Tejada, Guillermo, Brandenburg, Klaus

“…The bacterial cell wall represents the primary target for antimicrobial agents. Microbial destruction is accompanied by the release of potent immunostimulatory…”
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Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence by Schaubeck, Monika, Clavel, Thomas, Calasan, Jelena, Lagkouvardos, Ilias, Haange, Sven Bastiaan, Jehmlich, Nico, Basic, Marijana, Dupont, Aline, Hornef, Mathias, von Bergen, Martin, Bleich, André, Haller, Dirk

“…Dysbiosis of the intestinal microbiota is associated with Crohn's disease (CD). Functional evidence for a causal role of bacteria in the development of chronic…”
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The intestinal epithelium as guardian of gut barrier integrity: The epithelium as a barrier to infection by Zhang, Kaiyi, Hornef, Mathias W., Dupont, Aline

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Stabilization but No Functional Influence of HIF-1α Expression in the Intestinal Epithelium during Salmonella Typhimurium Infection by Robrahn, Laura, Dupont, Aline, Jumpertz, Sandra, Zhang, Kaiyi, Holland, Christian H, Guillaume, Joël, Rappold, Sabrina, Roth, Johanna, Cerovic, Vuk, Saez-Rodriguez, Julio, Hornef, Mathias W, Cramer, Thorsten

“…Hypoxia-inducible transcription factor 1 (HIF-1) has been shown to enhance microbial killing and ameliorate the course of bacterial infections. While the…”
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Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host by Zhang, Kaiyi, Repnik, Urska, Diab, Nour, Friske, Daniel, Pütz, Andreas, Bachmann, Alina Z, Gubbi, Narasimha Murthy Keshava Prasad, Hensel, Michael, Förstner, Konrad U, Westermann, Alexander J, Dupont, Aline, Hornef, Mathias W

“…The intestinal epithelium is the first line of defense against enteric pathogens. Removal of infected cells by exfoliation prevents mucosal translocation and…”
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Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes by Zou, Mangge, Pezoldt, Joern, Mohr, Juliane, Philipsen, Lars, Leufgen, Andrea, Cerovic, Vuk, Wiechers, Carolin, Pils, Marina, Ortiz, Diego, Hao, Lianxu, Yang, Juhao, Beckstette, Michael, Dupont, Aline, Hornef, Mathias, Dersch, Petra, Strowig, Till, Müller, Andreas J., Raila, Jens, Huehn, Jochen

“…Gut-draining mesenteric and celiac lymph nodes (mLNs and celLNs) critically contribute to peripheral tolerance toward food and microbial antigens by supporting…”
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Synthetic Anti-lipopolysaccharide Peptides (SALPs) as Effective Inhibitors of Pathogen-Associated Molecular Patterns (PAMPs) by Correa, Wilmar, Heinbockel, Lena, Martinez-de-Tejada, Guillermo, Sánchez, Susana, Garidel, Patrick, Schürholz, Tobias, Mier, Walter, Dupont, Aline, Hornef, Mathias, Gutsmann, Thomas, Mauss, Karl, Weindl, Günther, Brandenburg, Klaus

“…Antimicrobial peptides (AMPs) are in the focus of scientific research since the 1990s. In most cases, the main aim was laid on the design of AMP to kill…”
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Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition by Fulde, Marcus, Sommer, Felix, Chassaing, Benoit, van Vorst, Kira, Dupont, Aline, Hensel, Michael, Basic, Marijana, Klopfleisch, Robert, Rosenstiel, Philip, Bleich, André, Bäckhed, Fredrik, Gewirtz, Andrew T., Hornef, Mathias W.

“…In Fig. 1d of this Letter, the third group along should have been labelled ‘WT’ rather than ‘ Tlr5 ’. This has been corrected online…”
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Intestinal mucus affinity and biological activity of an orally administered antibacterial and anti-inflammatory peptide by Dupont, Aline, Kaconis, Yani, Yang, Ines, Albers, Thorben, Woltemate, Sabrina, Heinbockel, Lena, Andersson, Mats, Suerbaum, Sebastian, Brandenburg, Klaus, Hornef, Mathias W

“…Antimicrobial peptides (AMP) provide protection from infection by pathogenic microorganisms and restrict bacterial growth at epithelial surfaces to maintain…”
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