Search Results - "Duong, Hao A."
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Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes
Published in Nature structural & molecular biology (01-02-2014)“…Autorepression of PER-encoding genes underlies the periodic fluctuations in expression that drive the circadian clock. New work shows that histone deacetylase…”
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A Molecular Mechanism for Circadian Clock Negative Feedback
Published in Science (American Association for the Advancement of Science) (17-06-2011)“…Circadian rhythms in mammals are generated by a feedback loop in which the three PERIOD (PER) proteins, acting in a large complex, inhibit the transcriptional…”
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Environmental circadian disruption re-writes liver circadian proteomes
Published in Nature communications (01-07-2024)“…Circadian gene expression is fundamental to the establishment and functions of the circadian clock, a cell-autonomous and evolutionary-conserved timing system…”
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Histone monoubiquitination by Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback
Published in Nature structural & molecular biology (01-10-2015)“…New data show that Clock–Bmal1, the central transcriptional activator that drives expression of circadian target genes, also recruits the Ddb1–Cullin-4…”
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Purification and analysis of PERIOD protein complexes of the mammalian circadian clock
Published in Methods in enzymology (01-01-2015)“…In mammals, circadian rhythms are generated at least in part by a cell-autonomous transcriptional feedback loop in which the three PERIOD (PER) and two…”
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Dorsal interacting protein 3 potentiates activation by Drosophila Rel homology domain proteins
Published in Developmental and comparative immunology (2008)“…Dorsal interacting protein 3 (Dip3) contains a MADF DNA-binding domain and a BESS protein interaction domain. The Dip3 BESS domain was previously shown to bind…”
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TALE Homeodomain Proteins Regulate Gonadotropin-releasing Hormone Gene Expression Independently and via Interactions with Oct-1
Published in The Journal of biological chemistry (16-07-2004)“…Gonadotropin-releasing hormone (GnRH) is the central regulator of reproductive function. Expression of the GnRH gene is confined to a rare population of…”
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Non-cell-autonomous inhibition of photoreceptor development by Dip3
Published in Developmental biology (01-11-2008)“…We show here that the Drosophila MADF/BESS domain transcription factor Dip3, which is expressed in differentiating photoreceptors, regulates neuronal…”
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Temporal orchestration of repressive chromatin modifiers by mammalian circadian clock PERIOD complexes
Published in Nature structural & molecular biology (12-01-2014)“…The mammalian circadian clock is built on a molecular feedback loop in which the PERIOD (PER) proteins, acting in a large, poorly-understood complex, repress…”
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Transformation of eye to antenna by misexpression of a single gene
Published in Mechanisms of development (01-01-2008)“…In Drosophila, the eye and antenna originate from a single epithelium termed the eye-antennal imaginal disc. Illumination of the mechanisms that subdivide this…”
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Histone mono-ubiquitination by a Clock–Bmal1 complex marks Per1 and Per2 genes for circadian feedback
Published in Nature structural & molecular biology (31-08-2015)“…Circadian rhythms in mammals are driven by a feedback loop in which the transcription factor Clock–Bmal1 activates expression of Per and Cry proteins, which…”
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