Search Results - "Dunston, Stanley M."

Allergic inflammation is augmented via histamine H4 receptor activation: the role of natural killer cells in vitro and in vivo by Ehling, Sarah, Roßbach, Kristine, Dunston, Stanley M, Stark, Holger, Bäumer, Wolfgang

“…Highlights • H4R activation induced NKp46+ cell chemotaxis in vitro and in vivo. • H4R activation enhanced CCL17 release from I-A/I-E+ cells co-localized with…”
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Deficient plakophilin-1 expression due to a mutation in PKP1 causes ectodermal dysplasia-skin fragility syndrome in Chesapeake Bay retriever dogs by Olivry, Thierry, Linder, Keith E, Wang, Ping, Bizikova, Petra, Bernstein, Joseph A, Dunston, Stanley M, Paps, Judy S, Casal, Margret L

“…In humans, congenital and hereditary skin diseases associated with epidermal cell-cell separation (acantholysis) are very rare, and spontaneous animal models…”
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Expression patterns of superficial epidermal adhesion molecules in an experimental dog model of acute atopic dermatitis skin lesions by Olivry, Thierry, Dunston, Stanley M.

“…Background The stratum corneum is critical for providing a functional skin barrier, especially in humans and dogs with atopic dermatitis. An effective barrier…”
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The novel high molecular weight Dermatophagoides farinae protein Zen‐1 is a major allergen in North American and European mite allergic dogs with atopic dermatitis by Olivry, Thierry, Dunston, Stanley M., Favrot, Claude, Prélaud, Pascal, Tsukui, Toshiroh

“…Background Atopic dogs with hypersensitivity to Dermatophagoides farinae (Df) have IgE recognizing high molecular weight (MW) allergens more often than the low…”
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Patch testing of experimentally sensitized beagle dogs: development of a model for skin lesions of atopic dermatitis by Olivry, Thierry, Deangelo, Kristin B, Dunston, Stanley M, Clarke, Katie B, Mccall, Catherine A

“…In humans with atopic dermatitis (AD), the epicutaneous application of allergens (atopy patch tests or APT) to which the patients are sensitized often results…”
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Proof of concept of the preventive efficacy of high‐dose recombinant mono‐allergen immunotherapy in atopic dogs sensitized to the Dermatophagoides farinae allergen Der f 2 by Olivry, Thierry, Paps, Judy S., Dunston, Stanley M.

“…Background Allergen immunotherapy is currently the only intervention proposed to specifically prevent clinical flares after allergen challenges. The low…”
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Clinical, histopathological and immunological characteristics of exfoliative cutaneous lupus erythematosus in 25 German short-haired pointers by Bryden, S.L, White, S.D, Dunston, S.M, Burrows, A.K, Olivry, T

“…Clinical, histopathological and immunological features of exfoliative cutaneous lupus erythematosus, an uncommon generalized exfoliative dermatitis occurring…”
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Stratum corneum removal facilitates experimental sensitization to mite allergens in atopic dogs by Olivry, Thierry, Wofford, Jessica, Paps, Judy S, Dunston, Stanley M

“…In humans with atopic dermatitis and in mouse models of IgE-mediated allergic diseases, evidence is mounting that the stratum corneum (SC) provides an…”
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Serum autoantibody profiles of IgA, IgE and IgM in canine pemphigus foliaceus by Bizikova, Petra, Olivry, Thierry, Mamo, Lisa B., Dunston, Stanley M.

“…Background Pemphigus foliaceus (PF) is the most common IgG‐mediated autoimmune skin disease in dogs. Studies of human PF have revealed the presence of other…”
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Evaluation of intraepidermal nerve fibres in the skin of normal and atopic dogs by Laprais, Aurore, Dunston, Stanley M., Torres, Sheila M. F., Favrot, Claude, Olivry, Thierry

“…Background Interest in intraepidermal nerve fibres (IENFs) is rising in human medicine, because variations in fibre density occur in some diseases and these…”
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Desmoglein-3 is a target autoantigen in spontaneous canine pemphigus vulgaris by Olivry, Thierry, Joubeh, Sohaila, Dunston, Stanley M., Nishiyama, Takafumi, Ghohestani, Reza F.

“…: Pemphigus vulgaris (PV) is an autoimmune blistering skin disease of humans and companion animals. In human patients, PV is associated with the production of…”
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Immunopathology of vesicular cutaneous lupus erythematosus in the rough collie and shetland sheepdog: a canine homologue of subacute cutaneous lupus erythematosus in humans by Jackson, H.A, Olivery, T, Berget, F, Dunston, S.M, Bonnefont, C, Chabanne, L

“…Clinical and histological features of an erosive disease in the rough collie and Shetland sheepdog are most consistent with a vesicular variant of cutaneous…”
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Canine epidermolysis bullosa acquisita: a retrospective study of 20 cases by Bizikova, Petra, Linder, Keith E., Wofford, Jessica A., Mamo, Lisa B., Dunston, Stanley M., Olivry, Thierry

“…Background Epidermolysis bullosa acquisita (EBA) is a rare autoimmune subepidermal blistering disease of dogs and humans. Objectives Our objectives were to…”
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Isotype determination of circulating autoantibodies in canine autoimmune subepidermal blistering dermatoses by Favrot, Claude, Dunston, Stanley M., Paradis, Manon, Olivry, Thierry

“…The three most common canine autoimmune blistering skin diseases (AISBD), bullous pemphigoid (BP), mucous membrane pemphigoid (MMP) and epidermolysis bullosa…”
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Investigations on the nature and pathogenicity of circulating antikeratinocyte antibodies in dogs with pemphigus foliaceus by Olivry, Thierry, Dunston, Stanley M, Walker, Robina H, Alhaidari, Zeineb, Messinger, Linda, Liu, Zhi

“…In humans with pemphigus foliaceus (PF), pathogenic autoantibodies are principally of IgG4 subclass and they cause superficial vesiculation when injected into…”
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Lack of detection of circulating skin-specific IgE autoantibodies in dogs with moderate or severe atopic dermatitis by Olivry, Thierry, Dunston, Stanley M., Pluchino, Kristen, Porter, Kyleigh, Hammerberg, Bruce

“…Human patients with atopic dermatitis (AD) commonly exhibit IgE reactivity to cutaneous self-antigens. The presence of serum IgE autoantibodies appears to…”
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Clinical and immunological heterogeneity of canine subepidermal blistering dermatoses with anti-laminin-332 (laminin-5) auto-antibodies by Olivry, Thierry, Bizikova, Petra, Dunston, Stanley M, Bond, Ross, Halliwell, Richard, Loeffler, Anette, Pucheu-Haston, Cherie M, Chen, Mei, Peter Marinkovich, M

“…Laminin-332 (laminin-5) is a basement membrane heterotrimeric protein composed of alpha-3, beta-3 and gamma-2 laminin chains. Laminin-332 polypeptides are…”
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Desmoglein-1 is a minor autoantigen in dogs with pemphigus foliaceus by Olivry, Thierry, LaVoy, Alora, Dunston, Stanley M., Brown, Rachel S., Lennon, Elizabeth M., Warren, Simon J., Prisayanh, Phillip, Müller, Eliane J., Suter, Maja M., Dean, Gregg A.

“…The majority of human patients with pemphigus foliaceus (PF) have circulating IgG autoantibodies that target conformational epitopes on the desmosomal cadherin…”
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A Spontaneous Canine Model of Mucous Membrane (Cicatricial) Pemphigoid, an Autoimmune Blistering Disease Affecting Mucosae and Mucocutaneous Junctions by Olivry, Thierry, Dunston, Stanley M, Schachter, Marianne, Xu, Luting, Nguyen, Ngon, Marinkovich, M.Peter, Chan, Lawrence S

“…Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering dermatosis of humans that was previously known as cicatricial pemphigoid. It is characterized…”
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A randomized controlled trial of misoprostol monotherapy for canine atopic dermatitis: effects on dermal cellularity and cutaneous tumour necrosis factor-alpha by Olivry, Thierry, Dunston, Stanley M., Rivierre, Christine, Jackson, Hilary A., Murphy, K. Marcy, Peters, Erin, Dean, Gregg A.

“…In this blinded randomized placebo‐controlled trial, 20 dogs with atopic dermatitis (AD) were given placebo (8 dogs) or misoprostol (12 dogs) at 5 µg kg−1,…”
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