Search Results - "Dunsing, Valentin"
-
1
Multicolor fluorescence fluctuation spectroscopy in living cells via spectral detection
Published in eLife (08-09-2021)“…Signaling pathways in biological systems rely on specific interactions between multiple biomolecules. Fluorescence fluctuation spectroscopy provides a powerful…”
Get full text
Journal Article -
2
Optimal fluorescent protein tags for quantifying protein oligomerization in living cells
Published in Scientific reports (13-07-2018)“…Fluorescence fluctuation spectroscopy has become a popular toolbox for non-disruptive analysis of molecular interactions in living cells. The quantification of…”
Get full text
Journal Article -
3
Serotonin signaling regulates actomyosin contractility during morphogenesis in evolutionarily divergent lineages
Published in Nature communications (08-09-2023)“…Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously…”
Get full text
Journal Article -
4
Mandipropamid as a chemical inducer of proximity for in vivo applications
Published in Nature chemical biology (01-01-2022)“…Direct control of protein interactions by chemically induced protein proximity holds great potential for both cell and synthetic biology as well as therapeutic…”
Get full text
Journal Article -
5
A Fluorescence Fluctuation Spectroscopy Assay of Protein-Protein Interactions at Cell-Cell Contacts
Published in Journal of visualized experiments (01-12-2018)“…A variety of biological processes involves cell-cell interactions, typically mediated by proteins that interact at the interface between neighboring cells. Of…”
Get full text
Journal Article -
6
Purely Polysaccharide-Based Biofilm Matrix Provides Size-Selective Diffusion Barriers for Nanoparticles and Bacteriophages
Published in Biomacromolecules (14-10-2019)“…Biofilms are complex mixtures of proteins, DNA, and polysaccharides surrounding bacterial communities as protective barriers that can be biochemically modified…”
Get full text
Journal Article -
7
Influenza A M2 recruits M1 to the plasma membrane: A fluorescence fluctuation microscopy study
Published in Biophysical journal (21-12-2021)“…Influenza A virus (IAV) is a respiratory pathogen that causes seasonal epidemics with significant mortality. One of the most abundant proteins in IAV particles…”
Get full text
Journal Article -
8
Spectral Detection Enables Multi-Color Fluorescence Fluctuation Spectroscopy Studies in Living Cells
Published in Biophysical journal (12-02-2021)Get full text
Journal Article -
9
A Fluorescence Fluctuation Spectroscopy Assay of Protein-Protein Interactions at Cell-Cell Contacts
Published in Journal of visualized experiments (01-12-2018)Get full text
Journal Article -
10
Direct evidence of amyloid precursor-like protein 1 trans interactions in cell-cell adhesion platforms investigated via fluorescence fluctuation spectroscopy
Published in Molecular biology of the cell (01-12-2017)“…The amyloid precursor-like protein 1 (APLP1) is a type I transmembrane protein that plays a role in synaptic adhesion and synaptogenesis. Past investigations…”
Get full text
Journal Article -
11
Benchmarking of novel green fluorescent proteins for the quantification of protein oligomerization in living cells
Published in PloS one (03-08-2023)“…Protein-protein-interactions play an important role in many cellular functions. Quantitative non-invasive techniques are applied in living cells to evaluate…”
Get full text
Journal Article -
12
Biomimetic asymmetric bacterial membranes incorporating lipopolysaccharides
Published in Biophysical journal (06-06-2023)“…Gram-negative bacteria are equipped with a cell wall that contains a complex matrix of lipids, proteins, and glycans, which form a rigid layer protecting…”
Get full text
Journal Article -
13
Pantoea stewartii WceF is a glycan biofilm-modifying enzyme with a bacteriophage tailspike-like fold
Published in The Journal of biological chemistry (01-01-2021)“…Pathogenic microorganisms often reside in glycan-based biofilms. Concentration and chain length distribution of these mostly anionic exopolysaccharides (EPS)…”
Get full text
Journal Article -
14
Phosphatidylserine Lateral Organization Influences the Interaction of Influenza Virus Matrix Protein 1 with Lipid Membranes
Published in Journal of virology (15-06-2017)“…Influenza A virus matrix protein 1 (M1) is an essential component involved in the structural stability of the virus and in the budding of new virions from…”
Get full text
Journal Article -
15
-
16
Direct Evidence of APLP1 Trans Interactions in Cell-Cell Adhesion Platforms Investigated via Fluorescence Fluctuation Spectroscopy
Published in Biophysical journal (02-02-2018)Get full text
Journal Article -
17
Transfer of polarity information via diffusion of Wnt ligands in C. elegans embryos
Published in Current biology (06-05-2024)“…Different signaling mechanisms concur to ensure robust tissue patterning and cell fate instruction during animal development. Most of these mechanisms rely on…”
Get more information
Journal Article -
18
Tutorial: fluorescence lifetime microscopy of membrane mechanosensitive Flipper probes
Published in Nature protocols (29-08-2024)“…Measuring forces within living cells remains a technical challenge. In this Tutorial, we cover the development of hydrophobic mechanosensing fluorescent probes…”
Get full text
Journal Article -
19
Design Parameters for Granzyme-Mediated Cytotoxic Lymphocyte Target-Cell Killing and Specificity
Published in Biophysical journal (04-08-2015)“…Cytotoxic lymphocytes are key elements of the immune system that are primarily responsible for targeting cells infected with intracellular pathogens, or cells…”
Get full text
Journal Article -
20
Amyloid precursor‐like protein 1 (APLP1) exhibits stronger zinc‐dependent neuronal adhesion than amyloid precursor protein and APLP2
Published in Journal of neurochemistry (01-04-2016)“…The amyloid precursor protein (APP) and its paralogs, amyloid precursor‐like protein 1 (APLP1) and APLP2, are metalloproteins with a putative role both in…”
Get full text
Journal Article