Search Results - "Dunphy, Gail"
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The Sry3 Y Chromosome Locus Elevates Blood Pressure and Renin-Angiotensin System Indexes
Published in Gender medicine (01-04-2011)“…Abstract Background Sex-determining region Y (Sry) is a transcription factor. Our research group has shown that there are multiple copies of Sry in…”
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2
Sry delivery to the adrenal medulla increases blood pressure and adrenal medullary tyrosine hydroxylase of normotensive WKY rats
Published in BMC cardiovascular disorders (26-02-2007)“…Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats that had the SHR Y chromosome locus…”
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3
The SHR Y-chromosome increases testosterone and aggression, but decreases serotonin as compared to the WKY Y-chromosome in the rat model
Published in Behavior genetics (01-09-2004)“…The Spontaneously Hypertensive Rat (SHR) model was used to test the hypothesis that a locus on the SHR Y-chromosome is responsible for increased aggression…”
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Testosterone Increases Myogenic Reactivity of Second-Order Mesenteric Arteries in both Defective and Normal Androgen Receptor Adult Male Rats
Published in Gender medicine (01-02-2011)“…Abstract Background Testosterone (T) and the androgen receptor (AR) are involved in mechanisms associated with hypertension and vessel reactivity. Objective To…”
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Spontaneously Hypertensive Rat Y Chromosome Increases Indexes of Sympathetic Nervous System Activity
Published in Hypertension (Dallas, Tex. 1979) (01-02-1997)“…Previous studies from our laboratory have demonstrated that the Y chromosome from the spontaneously hypertensive rat (SHR) is responsible for a significant…”
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Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats
Published in Blood pressure (2000)“…The objective of this paper was to test the hypothesis that testosterone (T) raises blood pressure (BP), which is associated with increased coronary…”
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Review of the Y chromosome, Sry and hypertension
Published in Steroids (01-11-2010)“…The following review examines the role of the SHR Y chromosome and specifically the Sry gene complex in hypertension and potential mechanisms that involve the…”
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Journal Article Conference Proceeding -
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Neonatal sympathectomy reduces adult blood pressure and cardiovascular pathology in Y chromosome consomic rats
Published in Blood pressure (1999)“…The hypothesis was tested that the sympathetic nervous system (SNS) developmentally influences circulating testosterone (T), systolic blood pressure (SBP) and…”
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Manifestations of Instrument-to-Instrument Variability on an Internal Control During Real-Time PCR
Published in The journal of applied laboratory medicine (01-07-2016)Get full text
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The effect of the SHR Y chromosome on voluntary running
Published in The FASEB journal (01-04-2007)“…This study tested the hypothesis that there is an increase in the amount of voluntary running performed by SHR/y vs.WKY rat strains. The SHR/y rat is a strain…”
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11
Novel biostable and biocompatible amphiphilic membranes
Published in Journal of biomedical materials research. Part A (01-10-2008)“…We determined the biostability and biocompatibility of two types of amphiphilic conetworks (APCNs): (1) hydrophilic poly(N,N‐dimethyl acrylamide) (PDMAAm) and…”
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Castration increases plasma aldosterone and urinary sodium in WKY and SHR/y Males
Published in The FASEB journal (2007)“…The SHR Y‐chromosome and testosterone (T) can increase blood pressure and may also influence renal sodium (Na) excretion. There is evidence that T is able to…”
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13
Adventitial contribution to restenosis after angioplasty
Published in The FASEB journal (01-03-2006)“…Remodeling of the vascular wall is a major contributor to restenosis after angioplasty. While the involvement of smooth muscle cells after angioplasty has been…”
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14
Sry gene expression in the sympathetic nervous system of the rat
Published in The FASEB journal (01-04-2009)“…Abstract only The Sry gene has a well established role in testes determination. However, we have reported Sry gene expression in the adult adrenal gland and…”
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15
Sry3 exogenously delivered to the WKY kidney increases the renal renin‐ angiotensin system
Published in The FASEB journal (01-04-2009)“…Abstract only Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in SHR and WKY rats with the SHR Y chromosome (SHR/y…”
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Acute and Chronic Stressors Differentially Affect Myogenic Reactivity of Mesenteric Arteries in Spontaneously Hypertensive Male Rats
Published in The FASEB journal (01-04-2009)“…Abstract only Acute and chronic stressors contribute differentially to the development of cardiovascular diseases involving blood pressure, vessel reactivity,…”
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Effects of Acute Stress on Blood Pressure, Catecholamines, and Renal Interlobar Artery Constriction in Spontaneously Hypertensive (SHR) and Normotensive (WKY) Male Rats
Published in The FASEB journal (01-04-2009)“…Abstract only Human cardiovascular diseases are often preceded by and exaggerated with stress, affecting blood pressure, catecholamines (CATS), and vessel…”
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Aged SHR/y Males Show Decreased Water Maze Performance Compared to WKY Males
Published in The FASEB journal (01-04-2007)“…Various animal models and test paradigms indicate that as age increases, learning and memory performance declines. In addition, the stress response can act…”
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Colony social stress differentially alters blood pressure and resistance-sized mesenteric artery reactivity in SHR/y and WKY male rats
Published in Stress (Amsterdam, Netherlands) (01-01-2011)“…Increased sympathetic nervous system (SNS) activity, testosterone, and spontaneously hypertensive rat Y chromosome (SHR Yc) play a role in a genetic model of…”
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Delivery of sry1, but not sry2, to the kidney increases blood pressure and sns indices in normotensive wky rats
Published in BMC physiology (05-06-2009)“…Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats with the SHR Y chromosome (SHR/y…”
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