Search Results - "Dunne, Jean"

Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection by Townsend, Liam, Dyer, Adam H, Jones, Karen, Dunne, Jean, Mooney, Aoife, Gaffney, Fiona, O'Connor, Laura, Leavy, Deirdre, O'Brien, Kate, Dowds, Joanne, Sugrue, Jamie A, Hopkins, David, Martin-Loeches, Ignacio, Ni Cheallaigh, Cliona, Nadarajan, Parthiban, McLaughlin, Anne Marie, Bourke, Nollaig M, Bergin, Colm, O'Farrelly, Cliona, Bannan, Ciaran, Conlon, Niall

“…Fatigue is a common symptom in those presenting with symptomatic COVID-19 infection. However, it is unknown if COVID-19 results in persistent fatigue in those…”
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Sustained VWF-ADAMTS-13 axis imbalance and endotheliopathy in long COVID syndrome is related to immune dysfunction by Fogarty, Helen, Ward, Soracha E., Townsend, Liam, Karampini, Ellie, Elliott, Stephanie, Conlon, Niall, Dunne, Jean, Kiersey, Rachel, Naughton, Aifric, Gardiner, Mary, Byrne, Mary, Bergin, Colm, O'Sullivan, Jamie M., Martin-Loeches, Ignacio, Nadarajan, Parthiban, Bannan, Ciaran, Mallon, Patrick W., Curley, Gerard F., Preston, Roger J.S., Rehill, Aisling M., Baker, Ross I., Cheallaigh, Cliona Ni, O'Donnell, James S., O’Connell, Niamh, Ryan, Kevin, Kenny, Dermot, Fazavana, Judicael

“…Prolonged recovery is common after acute SARS-CoV-2 infection; however, the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown…”
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Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health by Townsend, Liam, Dyer, Adam H, Naughton, Aifric, Kiersey, Rachel, Holden, Dean, Gardiner, Mary, Dowds, Joanne, O'Brien, Kate, Bannan, Ciaran, Nadarajan, Parthiban, Dunne, Jean, Martin-Loeches, Ignacio, Fallon, Padraic G, Bergin, Colm, O'Farrelly, Cliona, Cheallaigh, Cliona Ni, Bourke, Nollaig M, Conlon, Niall

“…The immunological and inflammatory changes following acute COVID-19 are hugely variable. Persistent clinical symptoms following resolution of initial…”
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Effect of Immunosuppression on the Immune Response to SARS-CoV-2 Infection and Vaccination by Leacy, Emma J, Teh, Jia Wei, O'Rourke, Aoife M, Brady, Gareth, Gargan, Siobhan, Conlon, Niall, Scott, Jennifer, Dunne, Jean, Phelan, Thomas, Griffin, Matthew D, Power, Julie, Mooney, Aoife, Naughton, Aifric, Kiersey, Rachel, Gardiner, Mary, O'Brien, Caroline, Mullan, Ronan, Flood, Rachael, Clarkson, Michael, Townsend, Liam, O'Shaughnessy, Michelle, Dyer, Adam H, Moran, Barry, Fletcher, Jean M, Zgaga, Lina, Little, Mark A

“…Immunosuppressive treatment in patients with rheumatic diseases can maintain disease remission but also increase risk of infection. Their response to severe…”
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Peripheral Inflammation and Cognitive Performance in Middle-Aged Adults With and Without Type 2 Diabetes: Results From the ENBIND Study by Dyer, Adam H, McKenna, Louise, Batten, Isabella, Jones, Karen, Widdowson, Matthew, Dunne, Jean, Conlon, Niall, Reilly, Richard, Woods, Conor P, O'Neill, Desmond, Gibney, James, Bourke, Nollaig M, Kennelly, Sean P

“…Midlife Type 2 Diabetes Mellitus (T2DM) is associated with a greater risk of dementia in later life. Peripheral inflammation and its impact on cognition is…”
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Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity by Phelan, Thomas, Dunne, Jean, Conlon, Niall, Cheallaigh, Clíona Ní, Abbott, W. Mark, Faba-Rodriguez, Raquel, Amanat, Fatima, Krammer, Florian, Little, Mark A., Hughes, Gerry, Bergin, Colm, Kerr, Colm, Sundaresan, Sudharshana, Long, Aideen, McCormack, William, Brady, Gareth

“…Serological assays have been widely employed during the coronavirus disease 2019 (COVID-19) pandemic to measure antibody responses to severe acute respiratory…”
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SARS-CoV-2 anti-nucleocapsid assay performance in healthcare workers at baseline and 6 months by Kerr, Colm, Allen, Niamh, Hughes, Gerry, Kelly, Martina, O’Rourke, Fiona, Lynagh, Yvonne, Dunne, Jean, Crowley, Brendan, Conlon, Niall, Bergin, Colm

“…Introduction Serological SARS-CoV-2 assays have an important role in guiding the pandemic response. This research aimed to compare the performance of 2…”
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Point of care detection of SARS-CoV-2 antibodies and neutralisation capacity-lateral flow immunoassay evaluation compared to commercial assay to inform potential role in therapeutic and surveillance practices by McGrath, Jonathan, O'Doherty, Laura, Conlon, Niall, Dunne, Jean, Brady, Gareth, Ibrahim, Aya, McCormack, William, Walsh, Cathal, Domegan, Lisa, Walsh, Shane, Kenny, Claire, Allen, Niamh, Fleming, Catherine, Bergin, Colm

“…As the COVID-19 pandemic moves towards endemic status, testing strategies are being de-escalated. A rapid and effective point of care test (POCT) assessment of…”
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SARS-CoV-2 Antibody Testing in Health Care Workers: A Comparison of the Clinical Performance of Three Commercially Available Antibody Assays by Allen, Niamh, Brady, Melissa, Carrion Martin, Antonio Isidro, Domegan, Lisa, Walsh, Cathal, Houlihan, Elaine, Kerr, Colm, Doherty, Lorraine, King, Joanne, Doheny, Martina, Griffin, Damian, Molloy, Maria, Dunne, Jean, Crowley, Vivion, Holmes, Philip, Keogh, Evan, Naughton, Sean, Kelly, Martina, O'Rourke, Fiona, Lynagh, Yvonne, Crowley, Brendan, de Gascun, Cillian, Holder, Paul, Bergin, Colm, Fleming, Catherine, Ni Riain, Una, Conlon, Niall

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are an excellent indicator of past COVID-19 infection. As the COVID-19 pandemic…”
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SARS-CoV-2 epidemiology, antibody dynamics, and neutralisation capacity in Irish healthcare workers in the era of booster COVID-19 vaccinations by McGrath, Jonathan, Kenny, Claire, Nielsen, Charlotte Salgaard, Domegan, Lisa, Walsh, Cathal, Rooney, Peadar, Walsh, Shane, Conlon, Niall, Brady, Gareth, Ibrahim, Aya, Dunne, Jean, McCormack, William, Corcoran, Niamh, Allen, Niamh, Fleming, Catherine, Bergin, Colm

“…The PRECISE Study, a multi-phase cross-sectional seroprevalence study of anti-SARS-CoV-2 antibodies in Irish healthcare workers (HCW) investigated: (1) risk…”
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Using Cerebrospinal Fluid Biomarkers To Enhance Diagnostic Testing For Alzheimer's Disease In A Tertiary Memory Service by Crowe, Andrew, Garcia-Gallardo, Angela, Ferguson, Damien, Dunne, Jean, Hutchinson, Siobhan

“…Abstract Background Cerebrospinal Fluid (CSF) biomarkers are useful in the definitive diagnosis of Alzheimer’s disease (AD) when basic investigations and…”
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Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity by Townsend, Liam, Dowds, Joanne, O'Brien, Kate, Sheill, Grainne, Dyer, Adam H, O'Kelly, Brendan, Hynes, John P, Mooney, Aoife, Dunne, Jean, Ni Cheallaigh, Cliona, O'Farrelly, Cliona, Bourke, Nollaig M, Conlon, Niall, Martin-Loeches, Ignacio, Bergin, Colm, Nadarajan, Parthiban, Bannan, Ciaran

“…Much is known about the acute infective process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of the coronavirus disease…”
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Immune response in vaccinated healthcare workers with frequent COVID-19 infections is characterised by blunted IFNγ and IL-2 responses to SARS-CoV-2 variants by Townsend, Liam, Dunne, Jean, Sui, Jacklyn, Sanchez Perez, Carla, McElheron, Matt, Reid, Cian, McCormack, William, Bergin, Colm, Fleming, Catherine, O'Farrelly, Cliona, Brady, Gareth, Conlon, Niall

“…Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. Despite widespread vaccination, some HCWs develop frequent symptomatic infection. We…”
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Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency by Gineau, Laure, Cognet, Céline, Kara, Nihan, Lach, Francis Peter, Dunne, Jean, Veturi, Uma, Picard, Capucine, Trouillet, Céline, Eidenschenk, Céline, Aoufouchi, Said, Alcaïs, Alexandre, Smith, Owen, Geissmann, Frédéric, Feighery, Conleth, Abel, Laurent, Smogorzewska, Agata, Stillman, Bruce, Vivier, Eric, Casanova, Jean-Laurent, Jouanguy, Emmanuelle

“…Natural killer (NK) cells are circulating cytotoxic lymphocytes that exert potent and nonredundant antiviral activity and antitumoral activity in the mouse;…”
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Prevalence of N-Methyl-d-Aspartate Receptor antibody (NMDAR-Ab) encephalitis in patients with first episode psychosis and treatment resistant schizophrenia on clozapine, a population based study by Kelleher, Eric, McNamara, Patricia, Dunne, Jean, Fitzmaurice, Brian, Heron, Elizabeth A., Whitty, Peter, Walsh, Richard, Mooney, Christina, Hogan, Denise, Conlon, Niall, Gill, Michael, Vincent, Angela, Doherty, Colin P., Corvin, Aiden

“…N-methyl-d-aspartate receptor antibody (NMDAR-Ab) encephalitis consensus criteria has recently been defined. We aimed to examine the prevalence of NMDAR-Ab…”
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The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis by Moran, Sarah M, Scott, Jennifer, Clarkson, Michael R, Conlon, Niall, Dunne, Jean, Griffin, Matthew D, Griffin, Tomas P, Groarke, Elizabeth, Holian, John, Judge, Conor, Wyse, Jason, McLoughlin, Kirsty, O'Hara, Paul V, Kretzler, Matthias, Little, Mark A

“…Up to 70% of patients with ANCA-associated vasculitis (AAV) develop GN, with 26% progressing to ESKD. Diagnostic-grade and noninvasive tools to detect active…”
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Lin−CD117+CD34+FcεRI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti‐IgE therapy by Ridge, Katie, Moran, Barry, Alvarado‐Vazquez, P. Abigail, Hallgren, Jenny, Little, Mark A., Irvine, Alan D., O'Farrelly, Cliona, Dunne, Jean, Finlay, Conor M., Conlon, Niall

“…Background Chronic spontaneous urticaria (CSU) is a common, debilitating skin disorder characterized by recurring episodes of raised, itchy and sometimes…”
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The effects of dimethyl fumarate and fingolimod on T-cell lymphocyte proliferation in patients with multiple sclerosis by Reynolds, Audrey, Gaughan, Maria, Holden, Dean, Redenbaugh, Vyanka, Dunne, Jean, Redmond, Janice, Conlon, Niall

“…Objective The disease-modifying therapies (DMT), dimethyl fumarate (DMF) and fingolimod (FTY) improve the outcomes in multiple sclerosis (MS) by reducing…”
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Mucosal-associated invariant T cells are depleted and functionally altered in patients with common variable immunodeficiency by Arduini, Serena, Dunne, Jean, Conlon, Niall, Feighery, Conleth, Doherty, Derek G

“…Abstract Common variable immunodeficiency (CVID) is a primary immunoglobulin deficiency characterized by recurrent infections and complications, including…”
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Kinetics of the Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response and Serological Estimation of Time Since Infection by Pelleau, Stéphane, Woudenberg, Tom, Rosado, Jason, Donnadieu, Françoise, Garcia, Laura, Obadia, Thomas, Gardais, Soazic, Elgharbawy, Yasmine, Velay, Aurelie, Gonzalez, Maria, Nizou, Jacques Yves, Khelil, Nizar, Zannis, Konstantinos, Cockram, Charlotte, Merkling, Sarah Hélène, Meola, Annalisa, Kerneis, Solen, Terrier, Benjamin, de Seze, Jerome, Planas, Delphine, Schwartz, Olivier, Dejardin, François, Petres, Stéphane, von Platen, Cassandre, Pellerin, Sandrine Fernandes, Arowas, Laurence, de Facci, Louise Perrin, Duffy, Darragh, Cheallaigh, Clíona Ní, Dunne, Jean, Conlon, Niall, Townsend, Liam, Duong, Veasna, Auerswald, Heidi, Pinaud, Laurie, Tondeur, Laura, Backovic, Marija, Hoen, Bruno, Fontanet, Arnaud, Mueller, Ivo, Fafi-Kremer, Samira, Bruel, Timothée, White, Michael

“…Abstract Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a complex antibody response that varies by orders of…”
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