Search Results - "Dunn, Lauren K"

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    Comparison of oral versus intravenous methadone on postoperative pain and opioid use after adult spinal deformity surgery: A retrospective, non-inferiority analysis by Esfahani, Kamilla, Tennant, William, Tsang, Siny, Naik, Bhiken I, Dunn, Lauren K

    Published in PloS one (21-07-2023)
    “…To compare efficacy of oral versus intravenous (IV) methadone on postoperative pain and opioid requirements after spine surgery. This was a retrospective,…”
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    Journal Article
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    Non-opioid analgesics: novel approaches to perioperative analgesia for major spine surgery by Dunn, Lauren K., MD, PhD, Durieux, Marcel E., MD, PhD, Nemergut, Edward C., MD

    “…Abstract Perioperative pain management is a significant challenge following major spine surgery. Many pathways contribute to perioperative pain, including…”
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    Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment by Dunn, Lauren K, Mohammad, Khalid S, Fournier, Pierrick G J, McKenna, C Ryan, Davis, Holly W, Niewolna, Maria, Peng, Xiang Hong, Chirgwin, John M, Guise, Theresa A

    Published in PloS one (03-09-2009)
    “…Most patients with advanced breast cancer develop bone metastases, which cause pain, hypercalcemia, fractures, nerve compression and paralysis. Chemotherapy…”
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    Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease by Stalvey, Michael S, Clines, Katrina L, Havasi, Viktoria, McKibbin, Christopher R, Dunn, Lauren K, Chung, W Joon, Clines, Gregory A

    Published in PloS one (13-11-2013)
    “…Low bone mass and increased fracture risk are recognized complications of cystic fibrosis (CF). CF-related bone disease (CFBD) is characterized by uncoupled…”
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    Perioperative Use of Intravenous Lidocaine by Dunn, Lauren K, Durieux, Marcel E

    Published in Anesthesiology (Philadelphia) (01-04-2017)
    “…Perioperative lidocaine infusion improves analgesia and recovery after some surgical procedures, possibly through systemic antiinflammatory effects. This…”
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    Pro-Con Debate: Role of Methadone in Enhanced Recovery After Surgery Protocols—Superior Analgesic or Harmful Drug? by D’Souza, Ryan S., Esfahani, Kamilla, Dunn, Lauren K.

    Published in Anesthesia and analgesia (01-07-2023)
    “…Enhanced recovery after surgery (ERAS) protocols are standardized and designed to provide superior analgesia, reduce opioid consumption, improve patient…”
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    Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis by Dunn, Lauren K., Chen, Ching-Jen, Taylor, Davis G., Esfahani, Kamilla, Brenner, Brian, Luo, Charles, Buell, Thomas J., Spangler, Sarah N., Buchholz, Avery L., Smith, Justin S., Shaffrey, Christopher I., Nemergut, Edward C., Durieux, Marcel E., Naik, Bhiken I.

    Published in Neurospine (01-12-2020)
    “…Objective This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain…”
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    Anesthetic management during transsphenoidal pituitary surgery by Esfahani, Kamilla, Dunn, Lauren K.

    Published in Current opinion in anaesthesiology (01-10-2021)
    “…Purpose of review Pituitary adenoma resections comprise a large proportion of intracranial tumor surgeries. This patient population is medically and…”
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    Incidence and Risk Factors for Chronic Postoperative Opioid Use After Major Spine Surgery: A Cross-Sectional Study With Longitudinal Outcome by Dunn, Lauren K., Yerra, Sandeep, Fang, Shenghao, Hanak, Mark F., Leibowitz, Maren K., Tsang, Siny, Durieux, Marcel E., Nemergut, Edward C., Naik, Bhiken I.

    Published in Anesthesia and analgesia (01-07-2018)
    “…BACKGROUND:Chronic opioid use is a significant public health concern. Surgery is a risk factor for developing chronic opioid use. Patients undergoing major…”
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    Incremental Cost-effectiveness Analysis on Length of Stay of an Enhanced Recovery After Spine Surgery Program: A Single-center, Retrospective Cohort Study by Naik, Bhiken I., Dunn, Lauren K., Wanchek, Tanya N.

    Published in Journal of neurosurgical anesthesiology (01-04-2023)
    “…Enhanced recovery after spine surgery (ERAS) is increasingly utilized to improve postoperative outcomes and reduce cost. There are limited data on the monetary…”
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    TGF-β-RI Kinase Inhibitor SD-208 Reduces the Development and Progression of Melanoma Bone Metastases by MOHAMMAD, Khalid S, JAVELAUD, Delphine, FOURNIER, Pierrick G. J, NIEWOLNA, Maria, RYAN MCKENNA, C, PENG, Xiang H, DUONG, Vu, DUNN, Lauren K, MAUVIEL, Alain, GUISE, Theresa A

    Published in Cancer research (Chicago, Ill.) (01-01-2011)
    “…Melanoma often metastasizes to bone where it is exposed to high concentrations of TGF-β. Constitutive Smad signaling occurs in human melanoma. Because TGF-β…”
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