Search Results - "Dunn, Katherine A"
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1
Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2019)“…Exclusive enteral nutrition (EEN) is recommended for children with mild to moderate Crohn’s disease (CD), but implementation is challenging. We compared EEN…”
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2
The relationship between fecal bile acids and microbiome community structure in pediatric Crohn’s disease
Published in The ISME Journal (01-03-2020)“…Gut microbiome community structure is associated with Crohn’s disease (CD) development and response to therapy. Bile acids (BAs) play a central role in…”
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3
Multilocus Genotyping Assays for Single Nucleotide Polymorphism-Based Subtyping of Listeria monocytogenes Isolates
Published in Applied and Environmental Microbiology (01-12-2008)“…Listeria monocytogenes is responsible for serious invasive illness associated with consumption of contaminated food and places a significant burden on public…”
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4
Improved inference of site-specific positive selection under a generalized parametric codon model when there are multinucleotide mutations and multiple nonsynonymous rates
Published in BMC evolutionary biology (14-01-2019)“…An excess of nonsynonymous substitutions, over neutrality, is considered evidence of positive Darwinian selection. Inference for proteins often relies on…”
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5
Seasonal assemblages and short-lived blooms in coastal north-west Atlantic Ocean bacterioplankton
Published in Environmental microbiology (01-10-2015)“…Summary Temperate oceans are inhabited by diverse and temporally dynamic bacterioplankton communities. However, the role of the environment, resources and…”
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6
A new time-scale for ray-finned fish evolution
Published in Proceedings of the Royal Society. B, Biological sciences (22-02-2007)“…(gar) and…”
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7
Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease
Published in Microbiome (15-01-2018)“…Crohn's disease (CD) has an unclear etiology, but there is growing evidence of a direct link with a dysbiotic microbiome. Many gut microbes have previously…”
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Antibiotic and antifungal use in pediatric leukemia and lymphoma patients are associated with increasing opportunistic pathogens and decreasing bacteria responsible for activities that enhance colonic defense
Published in Frontiers in cellular and infection microbiology (27-07-2022)“…Due to decreased immunity, both antibiotics and antifungals are regularly used in pediatric hematologic-cancer patients as a means to prevent severe infections…”
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BiomeNet: a Bayesian model for inference of metabolic divergence among microbial communities
Published in PLoS computational biology (01-11-2014)“…Metagenomics yields enormous numbers of microbial sequences that can be assigned a metabolic function. Using such data to infer community-level metabolic…”
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10
The gastrointestinal antibiotic resistome in pediatric leukemia and lymphoma patients
Published in Frontiers in cellular and infection microbiology (24-02-2023)“…Most children with leukemia and lymphoma experience febrile neutropenia. These are treated with empiric antibiotics that include β-lactams and/or vancomycin…”
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11
Personalised azithromycin+metronidazole (PAZAZ), in combination with standard induction therapy, to achieve a faecal microbiome community structure and metagenome changes associated with sustained remission in paediatric Crohn’s disease (CD): protocol of a pilot study
Published in BMJ open (01-02-2023)“…IntroductionEarly relapse in Crohn’s disease (CD) is associated with a more severe disease course. The microbiome plays a crucial role, yet strategies…”
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12
Improving evolutionary models for mitochondrial protein data with site-class specific amino acid exchangeability matrices
Published in PloS one (31-01-2013)“…Adequate modeling of mitochondrial sequence evolution is an essential component of mitochondrial phylogenomics (comparative mitogenomics). There is wide…”
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13
BioMiCo: a supervised Bayesian model for inference of microbial community structure
Published in Microbiome (10-03-2015)“…Microbiome samples often represent mixtures of communities, where each community is composed of overlapping assemblages of species. Such mixtures are complex,…”
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14
The Challenge of Clinical Research and Suicidality: Participant Feedback on a Safety Protocol
Published in The journal of clinical psychiatry (15-05-2023)“…Clinical studies of depression have historically excluded participants with suicidal ideation. Research participant safety protocols are critical to allow for…”
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The impact of the host intestinal microbiome on carcinogenesis and the response to chemotherapy
Published in Future oncology (London, England) (01-11-2021)“…The microbiome consists of all microbes present on and within the human body. An unbalanced, or ‘dysbiotic’ intestinal microbiome is associated with…”
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Darwinian Adaptation of Proteorhodopsin to Different Light Intensities in the Marine Environment
Published in Proceedings of the National Academy of Sciences - PNAS (12-10-2004)“…Proteorhodopsin, a retinal-binding protein, represents a potentially significant source of light-driven energy production in the world's oceans. The…”
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17
Bacterial Taxa and Functions Are Predictive of Sustained Remission Following Exclusive Enteral Nutrition in Pediatric Crohn’s Disease
Published in Inflammatory bowel diseases (18-06-2020)“…Abstract Background The gut microbiome is extensively involved in induction of remission in pediatric Crohn’s disease (CD) patients by exclusive enteral…”
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18
Metabolome Changes With Diet-Induced Remission in Pediatric Crohn’s Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2022)“…The Crohn’s disease (CD) exclusion diet (CDED) plus partial enteral nutrition (PEN) and exclusive enteral nutrition (EEN) both induce remission in pediatric…”
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Neurosurgery Resident Wellness and Recovery from Burnout: A 39-Year Single-Institution Experience
Published in World neurosurgery (01-06-2020)“…Physician burnout in neurosurgery is highly prevalent and occurs most severely during residency. Although earlier assessments have identified stressors…”
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20
Dietary Therapy Reduces Pro-inflammatory Microbiome Features in Paediatric Crohn’s Disease
Published in Journal of Crohn's and colitis (10-05-2022)Get full text
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