Search Results - "Dunlea, Danielle M"

Characterization of the Inflammatory Response to Severe COVID-19 Illness by McElvaney, Oliver J, McEvoy, Natalie L, McElvaney, Oisín F, Carroll, Tomás P, Murphy, Mark P, Dunlea, Danielle M, Ní Choileáin, Orna, Clarke, Jennifer, O'Connor, Eoin, Hogan, Grace, Ryan, Daniel, Sulaiman, Imran, Gunaratnam, Cedric, Branagan, Peter, O'Brien, Michael E, Morgan, Ross K, Costello, Richard W, Hurley, Killian, Walsh, Seán, de Barra, Eoghan, McNally, Cora, McConkey, Samuel, Boland, Fiona, Galvin, Sinead, Kiernan, Fiona, O'Rourke, James, Dwyer, Rory, Power, Michael, Geoghegan, Pierce, Larkin, Caroline, O'Leary, Ruth Aoibheann, Freeman, James, Gaffney, Alan, Marsh, Brian, Curley, Gerard F, McElvaney, Noel G

“…Coronavirus disease (COVID-19) is a global threat to health. Its inflammatory characteristics are incompletely understood. To define the cytokine profile of…”
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Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia by McCarthy, Cormac, Dunlea, Danielle M, Saldova, Radka, Henry, Michael, Meleady, Paula, McElvaney, Oliver J, Marsh, Brian, Rudd, Pauline M, Reeves, Emer P, McElvaney, Noel G

“…To the Editor: Community-acquired pneumonia (CAP) is a common acute infection of the lung parenchyma that is diagnosed by clinical features of cough, fever,…”
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Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity by Reeves, Emer P, Dunlea, Danielle M, McQuillan, Karen, O'Dwyer, Ciara A, Carroll, Tomás P, Saldova, Radka, Akepati, Prithvi Reddy, Wormald, Mark R, McElvaney, Oliver J, Shutchaidat, Vipatsorn, Henry, Michael, Meleady, Paula, Keenan, Joanne, Liberti, Derek C, Kotton, Darrell N, Rudd, Pauline M, Wilson, Andrew A, McElvaney, Noel G

“…Alpha-1 antitrypsin (AAT) is an acute phase protein that possesses immune-regulatory and anti-inflammatory functions independent of antiprotease activity. AAT…”
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Ataluren, a New Therapeutic for Alpha-1 Antitrypsin-Deficient Individuals with Nonsense Mutations by Reeves, Emer P, O'Dwyer, Ciara A, Dunlea, Danielle M, Wormald, Mark R, Hawkins, Padraig, Alfares, Mohammad, Kotton, Darrell N, Rowe, Steven M, Wilson, Andrew A, McElvaney, Noel G

“…After sequencing of all coding exons (II-V) of the SERPINA1 gene, the patient was identified as homozygous for the Q0bolton mutation, with two PTCs at amino…”
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Brief Report: Genetic Variation of the α1‐Antitrypsin Gene Is Associated With Increased Autoantibody Production in Rheumatoid Arthritis by McCarthy, Cormac, Orr, Carl, Fee, Laura T., Carroll, Tomás P., Dunlea, Danielle M., Hunt, David J. L., Dunne, Eimear, O'Connell, Paul, McCarthy, Geraldine, Kenny, Dermot, Fearon, Ursula, Veale, Douglas J., Reeves, Emer P., McElvaney, Noel G.

“…Objective To examine the prevalence of α1‐antitrypsin deficiency (AATD) in rheumatoid arthritis (RA), and to determine whether AATD is associated with higher…”
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Brief Report: Genetic Variation of the α 1 -Antitrypsin Gene Is Associated With Increased Autoantibody Production in Rheumatoid Arthritis by McCarthy, Cormac, Orr, Carl, Fee, Laura T, Carroll, Tomás P, Dunlea, Danielle M, Hunt, David J L, Dunne, Eimear, O'Connell, Paul, McCarthy, Geraldine, Kenny, Dermot, Fearon, Ursula, Veale, Douglas J, Reeves, Emer P, McElvaney, Noel G

“…To examine the prevalence of α -antitrypsin deficiency (AATD) in rheumatoid arthritis (RA), and to determine whether AATD is associated with higher levels of…”
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The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals by Dunlea, Danielle M, Fee, Laura T, McEnery, Thomas, McElvaney, Noel G, Reeves, Emer P

“…Alpha-1 antitrypsin (AAT) is the most abundant serine protease inhibitor circulating in the blood. AAT deficiency (AATD) is an autosomal codominant condition…”
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Brief Report: Genetic Variation of the [alpha]1-Antitrypsin Gene Is Associated With Increased Autoantibody Production in Rheumatoid Arthritis by McCarthy, Cormac, Orr, Carl, Fee, Laura T, Carroll, Tomás P, Dunlea, Danielle M, Hunt, David J L, Dunne, Eimear, O'Connell, Paul, McCarthy, Geraldine, Kenny, Dermot, Fearon, Ursula, Veale, Douglas J, Reeves, Emer P, McElvaney, Noel G

“…Objective To examine the prevalence of [alpha]1-antitrypsin deficiency (AATD) in rheumatoid arthritis (RA), and to determine whether AATD is associated with…”
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Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function by Reeves, Emer P, McCarthy, Cormac, McElvaney, Oliver J, Vijayan, Maya Sakthi N, White, Michelle M, Dunlea, Danielle M, Pohl, Kerstin, Lacey, Noreen, McElvaney, Noel G

“…Cystic fibrosis (CF) is a multisystem disorder with significantly shortened life expectancy. The major cause of mortality and morbidity is lung disease with…”
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