Search Results - "Dunkel, Petra"

Photoremovable Protecting Groups by Dunkel, Petra

“…Photoremovable protecting groups (PPGs) (also often called photocages in the literature) are used for temporary inactivation of biologically active substrates…”
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Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes by Carpéné, Christian, Viana, Pénélope, Iffiú-Soltesz, Zsuzsa, Tapolcsányi, Pál, Földi, Anna Ágota, Mátyus, Péter, Dunkel, Petra

“…Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells. These…”
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Suzuki-aza-Wittig, Suzuki-condensation and aza-Wittig-electrocyclic ring-closure tandem reactions for synthesis of fused nitrogen-containing ring systems by Krajsovszky, Gábor, Károlyházy, László, Dunkel, Petra, Boros, Sándor, Grillo, Antonino, Mátyus, Péter

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Targeted Cancer Therapy Using Compounds Activated by Light by Dunkel, Petra, Ilaš, Janez

“…Cancer chemotherapy is affected by a modest selectivity and toxic side effects of pharmacological interventions. Among novel approaches to overcome this…”
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Synthesis of novel 1-methyl-1H-pyridazino[3,4-b]indoles by Riedl, Zsuzsanna, Monsieurs, Katrien, Krajsovszky, Gábor, Dunkel, Petra, Maes, Bert U.W., Tapolcsányi, Pál, Egyed, Orsolya, Boros, Sándor, Mátyus, Péter, Pieters, Luc, Lemière, Guy L.F., Hajós, György

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Synthesis and characterization of 8-aminoquinoline photocages for biological applications by Kontra, Bence, Bogdán, Dóra, Alaghehmand, Behta, Csomos, Attila, Dunkel, Petra

“…[Display omitted] Inspired by the 8-dimethylaminoquinoline (8-DMAQ) caging chromophore, photocleavable 8-aminoquinoline derivatives were prepared with the aim…”
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Covalent Inhibitors of KEAP1 with Exquisite Selectivity by Fejes, Imre, Markacz, Piroska, Tatai, Janos, Rudas, Monika, Dunkel, Petra, Gyuris, Mario, Nyerges, Miklos, Provost, Nicolas, Duvivier, Valérie, Delerive, Philippe, Martiny, Virginie, Bristiel, Alexandra, Vidal, Brice, Richardson, William, Rothweiler, Elisabeth M, Tranberg-Jensen, Jeppe, Manning, Charlotte E, Sweeney, Melissa N, Chalk, Rod, Huber, Kilian V M, Bullock, Alex N, Herner, Andras, Seedorf, Klaus, Vinson, Cedric, Weber, Csaba, Kotschy, Andras

“…The NRF2-KEAP1 interaction is central for cytoprotection against stresses, giving it high clinical significance. Covalent modification of KEAP1 is an efficient…”
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C(sp 3 )-H cyclizations of 2-(2-vinyl)phenoxy- tert -anilines by Dunkel, Petra, Bogdán, Dóra, Deme, Ruth, Zimber, Ádám, Ballayová, Veronika, Csizmadia, Eszter, Kontra, Bence, Kalydi, Eszter, Bényei, Attila, Mátyus, Péter, Mucsi, Zoltán

“…1,5-hydride transfer-triggered cyclization reactions offering a robust method for C(sp )-C(sp ) coupling and the synthesis of tetrahydroquinolines have been…”
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Photoinduced Electron Transfer (PET)‐Mediated Fragmentation of Picolinium‐Derived Redox Probes by Dunkel, Petra, Barosi, Anna, Dhimane, Hamid, Maurel, François, Dalko, Peter I.

“…The photolysis of covalently linked N‐alkyl picolinium phenylacetate—carbazole dyads was analyzed experimentally and by using density functional theory (DFT)…”
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Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis by Dunkel, Petra, Chai, Christina Ll, Sperlágh, Beáta, Huleatt, Paul B, Mátyus, Péter

“…According to the definition of the Committee to Identify Neuroprotective Agents in Parkinson's Disease (CINAPS), "neuroprotection would be any intervention…”
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3-Aminopropylazetidines: facile synthesis and application for medicinal chemical purposes by Bogdán, Dóra, Kontra, Bence, Csomos, Attila, Kovács, Ervin, Mucsi, Zoltán, Dunkel, Petra

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Synthesis of 8-aminoquinoline chelating moieties for chemosensor molecules by Csomos, Attila, Pantl, Orsolya, Dunkel, Petra, Bogdán, Dóra, Steckel, Arnold, Schlosser, Gitta, Mucsi, Zoltán, Kovács, Ervin

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Quinoline-derived two-photon sensitive quadrupolar probes by Dunkel, Petra, Tran, Christine, Gallavardin, Thibault, Dhimane, Hamid, Ogden, David, Dalko, Peter I

“…The first quadrupolar 8-dimethylaminoquinoline-derived 6-(8-DMAQ-OAc)2 (1c) and 5-(8-DMAQ-OAc)2 (2c) photosensitive probes underwent photolysis under UV (365…”
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C(sp)-H cyclizations of 2-(2-vinyl)phenoxy--anilines by Dunkel, Petra, Bogdán, Dóra, Deme, Ruth, Zimber, Ádám, Ballayová, Veronika, Csizmadia, Eszter, Kontra, Bence, Kalydi, Eszter, Bényei, Attila, Mátyus, Péter, Mucsi, Zoltán

“…1,5-hydride transfer-triggered cyclization reactions offering a robust method for C(sp 3 )-C(sp 3 ) coupling and the synthesis of e.g. tetrahydroquinolines…”
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Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease by Baranyi, Mária, Porceddu, Pier Francesca, Gölöncsér, Flóra, Kulcsár, Szabina, Otrokocsi, Lilla, Kittel, Ágnes, Pinna, Annalisa, Frau, Lucia, Huleatt, Paul B, Khoo, Mui-Ling, Chai, Christina L L, Dunkel, Petra, Mátyus, Peter, Morelli, Micaela, Sperlágh, Beáta

“…Mitochondrial dysfunction, oxidative stress and their interplay are core pathological features of Parkinson's disease. In dopaminergic neurons, monoamines and…”
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Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions by Barosi, Anna, Dunkel, Petra, Guénin, Erwann, Lalatonne, Yoann, Zeitoun, Philippe, Fitton, Isabelle, Journé, Clément, Bravin, Alberto, Maruani, Antoine, Dhimane, Hamid, Motte, Laurence, Dalko, Peter I

“…An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A…”
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Synthesis of novel fused azecine ring systems through application of the tert-amino effect by Dunkel, Petra, Túrós, György, Bényei, Attila, Ludányi, Krisztina, Mátyus, Péter

“…Novel fused azecine ring systems were synthesized via the microwave-assisted thermal isomerization of terphenyl or biphenyl-pyridazine compounds possessing a…”
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Towards dual antithrombotic compounds - balancing thrombin inhibitory and fibrinogen GPIIb/IIIa binding inhibitory activities of 2,3-dihydro-1,4-benzodioxine derivatives through regio- and stereoisomerism by Ilić, Miloš, Dunkel, Petra, Ilaš, Janez, Chabielska, Ewa, Zakrzeska, Agnieszka, Mátyus, Péter, Kikelj, Danijel

“…Enantiomers of 2,3-dihydro-1,4-benzodioxine derivatives possessing both thrombin and fibrinogen GPIIb/IIIa binding inhibitory activities were prepared from…”
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5-Aryl-dimethylamino quinoline-derived two-photon sensitive probes by Tran, Christine, Dunkel, Petra, Dhimane, Hamid, Ogden, David, Dalko, Peter I.

“…2-Hydroxymethylene-8-dimethylamino quinoline-(DMAQ) derived photosensitive probes were prepared and tested under 366 nm and 730 nm 150 fs pulsed ("two-photon")…”
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Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey by Dunkel, Petra, Balogh, Balázs, Meleddu, Rita, Maccioni, Elias, Gyires, Klára, Mátyus, Péter

“…Vascular adhesion protein-1 (VAP-1)/semicarbazide-sensitive amine oxidase (SSAO) is an adhesion protein involved in leukocyte trafficking and inflammatory…”
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