Search Results - "Dunham, Philip B."

Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter by Race, J E, Makhlouf, F N, Logue, P J, Wilson, F H, Dunham, P B, Holtzman, E J

“…We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76%…”
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Na+-inhibitory sites of the Na+/H+ exchanger are Li+ substrate sites by Dunham, Philip B, Kelley, Scott J, Logue, Paul J, Mutolo, Michael J, Milanick, Mark A

“…Amiloride-inhibitable Li+ influx in dog red blood cells is mediated by the Na+/H+ exchanger, NHE. However, there are substantial differences between the…”
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The KCl cotransporter isoform KCC3 can play an important role in cell growth regulation by Shen, M R, Chou, C Y, Hsu, K F, Liu, H S, Dunham, P B, Holtzman, E J, Ellory, J C

“…The KCl cotransporter (KCC) plays a significant role in the ionic and osmotic homeostasis of many cell types. Four KCC isoforms have been cloned. KCC1 and KCC4…”
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Cell shrinkage activates Na +/H + exchange in dog red cells by relieving inhibition of exchange by Na + in isotonic medium by Dunham, Philip B

“…Na +/H + exchangers (NHE) are widely distributed transporters responsible for regulation of cell volume and pH. In isotonic medium, NHE is often low or…”
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Extracellular Na+ inhibits Na+/H+ exchange: cell shrinkage reduces the inhibition by Dunham, Philip B, Kelley, Scott J, Logue, Paul J

“…Na+/H+ exchangers (NHE) are ubiquitous transporters participating in regulation of cell volume and pH. Cell shrinkage, acidification, and growth factors…”
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Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans by Holtzman, E J, Kumar, S, Faaland, C A, Warner, F, Logue, P J, Erickson, S J, Ricken, G, Waldman, J, Dunham, P B

“…We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegans K-Cl cotransporters. The pig and human homologs are 94% identical and…”
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Stimulation of membrane serine-threonine phosphatase in erythrocytes by hydrogen peroxide and staurosporine by Bize, I, Muñoz, P, Canessa, M, Dunham, P B

“…Indirect evidence has suggested that K-Cl cotransport in human and sheep erythrocytes is activated physiologically by a serine-threonine phosphatase. It is…”
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Oxygen sensing and K+‐Cl− cotransport by Dunham, Philip B.

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X-Linked Recessive Nephrolithiasis with Renal Failure by Frymoyer, Paul A, Scheinman, Steven J, Dunham, Philip B, Jones, David B, Hueber, Paul, Schroeder, Edward T

“…HEREDITARY nephrolithiasis occurs as a consequence of a number of conditions, including distal renal tubular acidosis, Bartter's syndrome, adenine…”
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Swelling activation of K-Cl cotransport in LK sheep erythrocytes : a three-state process by DUNHAM, P. B, KLIMCZAK, J, LOGUE, P. J

“…K-Cl cotransport in LK sheep erythrocytes is activated by osmotic swelling and inhibited by shrinkage. The mechanism by which changes in cell volume are…”
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Effects of ionic strength on the regulation of Na/H exchange and K-Cl cotransport in dog red blood cells by Parker, J C, Dunham, P B, Minton, A P

“…Dog red cell membranes contain two distinct volume-sensitive transporters: swelling-activated K-Cl cotransport and shrinkage-activated Na/H exchange. Cells…”
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The KCI Cotransporter Isoform KCC3 Can Play an Important Role in Cell Growth Regulation by Shen, Meng-Ru, Chou, Cheng-Yang, Hsu, Keng-Fu, Liu, Hsiao-Sheng, Dunham, Philip B., Holtzman, Eli J., Ellory, J. Clive

“…The KCl cotransporter (KCC) plays a significant role in the ionic and osmotic homeostasis of many cell types. Four KCC isoforms have been cloned. KCC1 and KCC4…”
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Lithium Efflux through the Na/K Pump in Human Erythrocytes by Dunham, Philip B., Senyk, Oksana

“…Active Li efflux from human erythrocytes was shown to be mediated by the Na/K pump: (i) intracellular Li (Lic) activated ouabain-sensitive K influx, and (ii) a…”
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Partial Purification of the Ouabain-Binding Component and of Na, K-ATPase from Human Red Cell Membranes by Dunham, Philip B., Hoffman, Joseph F.

“…Ghosts of human red cells were incubated with tritiated ouabain in the presence of ATP, Mg, and Na, conditions under which ouabain binds with high specificity…”
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Regulation of cellular osmolarity and volume in Tetrahymena by Stoner, L C, Dunham, P B

“…Tetrahymena pyrifor mis are hyperosmotic to external media of osmolarities from 2 to 171 m-osmole/1. The intracellular osmolarity, determined by freezing-point…”
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Attack of Sea Urchin Eggs by Dogfish Phagocytes: Model of Phagocyte-Mediated Cellular Cytotoxicity by Weissmann, Gerald, Finkelstein, Morris C., Csernansky, John, Quigley, James P., Quinn, Ruth S., Techner, Lee, Troll, Walter, Dunham, Philip B.

“…To test whether lysosomal degranulation of phagocytes is associated with antibody-dependent cytotoxicity, eggs of Arbacia punctulata were used as targets for…”
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Adenosine triphosphatase and active cation transport in red blood cell membranes by Dunham, P B, Gunn, R B

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Reconstitution of calyculin-inhibited K-Cl cotransport in dog erythrocyte ghosts by exogenous PP-1 by Krarup, T, Dunham, P B

“…Osmotic swelling of dog and other mammalian erythrocytes activates Cl-dependent K transport, K-Cl cotransport. This activation can be abolished by nanomolar…”
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CONTRACTION OF ISOLATED CONTRACTILE VACUOLES FROM AMOEBA PROTEUS by Prusch, Robert D., Dunham, Philip B.

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Mechanism of swelling activation of K-Cl cotransport in inside-out vesicles of LK sheep erythrocyte membranes by Kelley, S J, Dunham, P B

“…Stimulation by swelling of K-Cl cotransport was studied in inside-out vesicles (IOVs) made from membranes of LK sheep erythrocytes. The purpose was to…”
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