Search Results - "Dunger, D. B."

The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort by Acerini, C L, Miles, H L, Dunger, D B, Ong, K K, Hughes, I A

“…Introduction: Recent studies in other European countries suggest that the prevalence of congenital cryptorchidism continues to increase. This study aimed to…”
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Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children by MERICQ, V, ONG, K. K, BAZAES, R, PENA, V, AVILA, A, SALAZAR, T, SOTO, N, IBIGUEZ, G, DUNGER, D. B

“…Insulin resistance and type 2 diabetes risk in human subjects who were small-for-gestational-age (SGA) at birth may be a consequence of rapid early postnatal…”
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Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants by Fisher, B.G., Thankamony, A., Hughes, I.A., Ong, K.K., Dunger, D.B., Acerini, C.L.

“…STUDY QUESTION What is the relationship between maternal paracetamol intake during the masculinisation programming window (MPW, 8–14 weeks of gestation) and…”
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Pathophysiology of postprandial hyperglycaemia in women with type 1 diabetes during pregnancy by Murphy, H. R., Elleri, D., Allen, J. M., Harris, J., Simmons, D., Rayman, G., Temple, R. C., Umpleby, A. M., Dunger, D. B., Haidar, A., Nodale, M., Wilinska, M. E., Hovorka, R.

“…Aims/hypothesis Although maternal hyperglycaemia is associated with increased risk of adverse pregnancy outcome, the mechanisms of postprandial hyperglycaemia…”
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Monitoring of concordance in growth hormone therapy by Kapoor, R R, Burke, S A, Sparrow, S E, Hughes, I A, Dunger, D B, Ong, K K, Acerini, C L

“…Concordance with growth hormone (GH) therapy in 75 children was objectively assessed using data on GP prescriptions over 12 months. 23% missed >2…”
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The relationship between Insulin-like Growth Factor 1, sex steroids and timing of the pubertal growth spurt by Cole, T.J., Ahmed, M.L., Preece, M.A., Hindmarsh, P., Dunger, D.B.

“…Summary Objective Progress through puberty involves a complex hormonal cascade, but the individual contributions of hormones, particularly IGF‐1, are unknown…”
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Which infancy growth parameters are associated with later adiposity? The Cambridge Baby Growth Study by Ong, Ken K., Cheng, Tuck Seng, Olga, L., Prentice, P. M., Petry, C. J., Hughes, I. A., Dunger, D. B.

“…Background: Highly consistent positive associations are reported between infancy growth and later obesity risk. However, it is unclear whether infancy growth…”
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The UK case-control study of cerebral oedema complicating diabetic ketoacidosis in children by EDGE, J. A, JAKES, R. W, ROY, Y, HAWKINS, M, WINTER, D, FORD-ADAMS, M. E, MURPHY, N. P, BERGOMI, A, WIDMER, B, DUNGER, D. B

“…Cerebral oedema complicating diabetic ketoacidosis (DKA) remains the major cause of morbidity and mortality in children with type 1 diabetes, but its aetiology…”
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Absorption patterns of meals containing complex carbohydrates in type 1 diabetes by Elleri, D., Allen, J. M., Harris, J., Kumareswaran, K., Nodale, M., Leelarathna, L., Acerini, C. L., Haidar, A., Wilinska, M. E., Jackson, N., Umpleby, A. M., Evans, M. L., Dunger, D. B., Hovorka, R.

“…Aims/hypothesis Successful postprandial glycaemia management requires understanding of absorption patterns after meals containing variable complex…”
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Validation of the continuous glucose monitoring sensor in preterm infants by Beardsall, K, Vanhaesebrouck, S, Ogilvy-Stuart, A L, Vanhole, C, VanWeissenbruch, M, Midgley, P, Thio, M, Cornette, L, Ossuetta, I, Palmer, C R, Iglesias, I, de Jong, M, Gill, B, de Zegher, F, Dunger, D B

“…Recent studies have highlighted the need for improved methods of monitoring glucose control in intensive care to reduce hyperglycaemia, without increasing the…”
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Insulin sensitivity and secretion in normal children related to size at birth, postnatal growth, and plasma insulin-like growth factor-I levels by ONG, K. K, PETRY, C. J, EMMETT, P. M, SANDHU, M. S, KIESS, W, HALES, C. N, NESS, A. R, DUNGER, D. B

“…Type 2 diabetes risk is associated with low birth weight, rapid weight gain during childhood, and shorter stature and lower circulating IGF-I levels in adults…”
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Multi‐parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes by Thompson, W. S., Pekalski, M. L., Simons, H. Z., Smyth, D. J., Castro‐Dopico, X., Guo, H., Guy, C., Dunger, D. B., Arif, S., Peakman, M., Wallace, C., Wicker, L. S., Todd, J. A, Ferreira, R. C.

“…Summary The appearance of circulating islet‐specific autoantibodies before disease diagnosis is a hallmark of human type 1 diabetes (T1D), and suggests a role…”
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First UK survey of paediatric type 2 diabetes and MODY by Ehtisham, S, Hattersley, A T, Dunger, D B, Barrett, T G

“…Aims: To estimate the UK prevalence of childhood type 2 diabetes and maturity onset diabetes of the young (MODY), and distinguish them from each other and from…”
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The risk and outcome of cerebral oedema developing during diabetic ketoacidosis by Edge, J A, Hawkins, M M, Winter, D L, Dunger, D B

“…BACKGROUND Cerebral oedema is a major cause of morbidity and mortality in children with insulin dependent diabetes. AIMS To determine the risk and outcome of…”
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Prevention and treatment of microvascular disease in childhood type 1 diabetes by Marcovecchio, M. L., Tossavainen, P. H., Dunger, D. B.

“…Introduction The incidence of type 1 diabetes (T1D) is increasing worldwide, particularly in children, and is associated with a significant burden, mainly…”
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ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents by Dunger, D B, Sperling, M A, Acerini, C L, Bohn, D J, Daneman, D, Danne, T P A, Glaser, N S, Hanas, R, Hintz, R L, Levitsky, L L, Savage, M O, Tasker, R C, Wolfsdorf, J I

“…Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus (TIDM). Mortality is predominantly…”
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Short-Term Administration of Pegvisomant Improves Hepatic Insulin Sensitivity and Reduces Soleus Muscle Intramyocellular Lipid Content in Young Adults With Type 1 Diabetes by Thankamony, A, Tossavainen, P. H, Sleigh, A, Acerini, C, Elleri, D, Dalton, R. N, Jackson, N. C, Umpleby, A. M, Williams, R. M, Dunger, D. B

“…Context: Data on the metabolic effects of GH derived from studies using GH suppression by pharmacological agents may not reflect selective actions. Objective:…”
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Current methods of transfer of young people with Type 1 diabetes to adult services by Kipps, S., Bahu, T., Ong, K., Ackland, F. M., Brown, R. S., Fox, C. T., Griffin, N. K., Knight, A. H., Mann, N. P., Neil, H. A. W., Simpson, H., Edge, J. A., Dunger, D. B.

“…Aims To determine the efficacy and patient perception of various transfer procedures from paediatric to adult diabetes services. Methods Comparison between…”
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Polycystic ovaries and associated clinical and biochemical features in young women by Michelmore, K. F., Balen, A. H., Dunger, D. B., Vessey, M. P.

“…OBJECTIVE To determine the prevalence of polycystic ovaries as identified by ultrasound in a group of young, postmenarcheal women in the normal population, and…”
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Adolescents' views and experiences of treatments for Type 2 diabetes: a qualitative study by Turner, K. M., Percival, J., Dunger, D. B., Olbers, T., Barrett, T., Shield, J. P. H.

“…Aim To explore adolescents' views and experiences of different treatments for Type 2 diabetes, in order to improve treatment concordance and consider how the…”
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