Search Results - "Duncan, Margaret J"
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Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis
Published in BMC genomics (31-10-2012)“…Porphyromonas gingivalis is a Gram-negative anaerobic bacterium associated with periodontal disease onset and progression. Genetic tools for the manipulation…”
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CovR and VicRK regulate cell surface biogenesis genes required for biofilm formation in Streptococcus mutans
Published in PloS one (12-03-2013)“…The two-component system VicRK and the orphan regulator CovR of Streptococcus mutans co-regulate a group of virulence genes associated with the synthesis of…”
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3
Role of sodium in the RprY-dependent stress response in Porphyromonas gingivalis
Published in PloS one (06-05-2013)“…Porphyromonas gingivalis is a Gram-negative oral anaerobe which is strongly associated with periodontal disease. Environmental changes in the gingival sulcus…”
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Two-component signal transduction systems in oral bacteria
Published in Journal of oral microbiology (01-01-2017)“…We present an overview of how members of the oral microbiota respond to their environment by regulating gene expression through two-component signal…”
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Enhanced Biofilm Formation and Loss of Capsule Synthesis: Deletion of a Putative Glycosyltransferase in Porphyromonas gingivalis
Published in Journal of Bacteriology (01-08-2006)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Using Tn-seq To Identify Pigmentation-Related Genes of Porphyromonas gingivalis: Characterization of the Role of a Putative Glycosyltransferase
Published in Journal of bacteriology (15-07-2017)“…Cellular pigmentation is an important virulence factor of the oral pathogen Pigmentation has been associated with many bacterial functions, including but not…”
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Post-translational regulation of a Porphyromonas gingivalis regulator
Published in Journal of oral microbiology (01-01-2018)“…Background: Bacteria use two-component signal transduction systems (among others) to perceive and respond to environmental changes. Within the genus…”
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Mechanisms by which Porphyromonas gingivalis evades innate immunity
Published in PloS one (03-08-2017)“…The oral cavity is home to unique resident microbial communities whose interactions with host immunity are less frequently studied than those of the intestinal…”
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Downregulation of GbpB, a Component of the VicRK Regulon, Affects Biofilm Formation and Cell Surface Characteristics of Streptococcus mutans
Published in Infection and Immunity (01-02-2011)“…The virulence of the dental caries pathogen Streptococcus mutans relies in part on the sucrose-dependent synthesis of and interaction with glucan, a major…”
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Histidine Kinase-Mediated Production and Autoassembly of Porphyromonas gingivalis Fimbriae
Published in Journal of Bacteriology (01-04-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Three‐Dimensional Humanized Model of the Periodontal Gingival Pocket to Study Oral Microbiome
Published in Advanced science (01-04-2023)“…The oral cavity contains distinct microenvironments that serve as oral barriers, such as the non‐shedding surface of the teeth (e.g., enamel), the epithelial…”
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12
Transglutaminase 2 is essential for adherence of Porphyromonas gingivalis to host cells
Published in Proceedings of the National Academy of Sciences - PNAS (08-04-2014)“…Porphyromonas gingivalis is the major causative agent of periodontitis, and it may also be involved in the development of systemic diseases (atherosclerosis,…”
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Translocation of Porphyromonas gingivalis Gingipain Adhesin Peptide A44 to Host Mitochondria Prevents Apoptosis
Published in Infection and Immunity (01-08-2010)“…Porphyromonas gingivalis, a Gram-negative oral anaerobe, is associated with periodontal diseases that, in some form, affect up to 80% of the U.S. population…”
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14
A two-component system regulates hemin acquisition in Porphyromonas gingivalis
Published in PloS one (05-09-2013)“…Porphyromonas gingivalis is a Gram-negative oral anaerobe associated with infection of the periodontia. The organism has a small number of two-component signal…”
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15
No man's land: Species‐specific formation of exclusion zones bordering Actinomyces graevenitzii microcolonies in nanoliter cultures
Published in MicrobiologyOpen (Weinheim) (01-01-2021)“…To survive within complex environmental niches, including the human host, bacteria have evolved intricate interspecies communities driven by competition for…”
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Oral Delivery of a Novel Recombinant Streptococcus mitis Vector Elicits Robust Vaccine Antigen-Specific Oral Mucosal and Systemic Antibody Responses and T Cell Tolerance
Published in PloS one (30-11-2015)“…The pioneer human oral commensal bacterium Streptococcus mitis has unique biologic features that make it an attractive mucosal vaccine or therapeutic delivery…”
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Correction: Oral Delivery of a Novel Recombinant Streptococcus mitis Vector Elicits Robust Vaccine Antigen-Specific Oral Mucosal and Systemic Antibody Responses and T Cell Tolerance
Published in PloS one (22-01-2016)“…(A) The signal peptide has an amino-terminal region (N), a hydrophobic core (H), a signal peptidase cleavage site (C), and an accessory Sec transport motif…”
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A regulation cascade controls expression of Porphyromonas gingivalis fimbriae via the FimR response regulator
Published in Molecular microbiology (01-10-2004)“…Summary Little is known about how Porphyromonas gingivalis, a Gram‐negative oral anaerobe, senses environmental changes, and how such information is…”
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Gene Expression in Porphyromonas gingivalis after Contact with Human Epithelial Cells
Published in Infection and Immunity (01-04-2005)“…Porphyromonas gingivalis, a gram-negative oral anaerobe, is strongly associated with adult periodontitis. The adherence of the organism to host epithelium…”
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Comparative Whole-Genome Analysis of Virulent and Avirulent Strains of Porphyromonas gingivalis
Published in Journal of Bacteriology (01-08-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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