Search Results - "Duncan, Jacque L"
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Interim Results from the International Trial of Second Sight's Visual Prosthesis
Published in Ophthalmology (Rochester, Minn.) (01-04-2012)“…Purpose This study evaluated the Argus II Retinal Prosthesis System (Second Sight Medical Products, Inc., Sylmar, CA) in blind subjects with severe outer…”
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Randomized Trial of Ciliary Neurotrophic Factor Delivered by Encapsulated Cell Intraocular Implants for Retinitis Pigmentosa
Published in American journal of ophthalmology (01-08-2013)“…Purpose To evaluate the safety and effect on visual function of ciliary neurotrophic factor delivered via an intraocular encapsulated cell implant for the…”
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Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial
Published in Ophthalmology (Rochester, Minn.) (01-10-2016)“…Purpose The Argus II Retinal Prosthesis System (Second Sight Medical Products, Inc, Sylmar, CA) was developed to restore some vision to patients blind as a…”
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Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment
Published in Investigative ophthalmology & visual science (06-04-2011)“…To study cone photoreceptor structure and function in patients with inherited retinal degenerations treated with sustained-release ciliary neurotrophic factor…”
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DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY PROVIDES ACCURATE OUTER NUCLEAR LAYER AND HENLE FIBER LAYER MEASUREMENTS
Published in Retina (Philadelphia, Pa.) (01-08-2015)“…The outer nuclear layer (ONL) contains photoreceptor nuclei, and its thickness is an important biomarker for retinal degenerations. Accurate ONL thickness…”
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Observation of cone and rod photoreceptors in normal subjects and patients using a new generation adaptive optics scanning laser ophthalmoscope
Published in Biomedical optics express (01-08-2011)“…We demonstrate the capability of a new generation adaptive optics scanning laser ophthalmoscope (AOSLO) to resolve cones and rods in normal subjects, and…”
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Cone Structure and Function in RPGR- and USH2A-Associated Retinal Degeneration
Published in American journal of ophthalmology (01-06-2023)“…To compare cone structure and function between RPGR- and USH2A-associated retinal degeneration. Retrospective, observational, cross-sectional study. This…”
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Adaptive optics retinal imaging: emerging clinical applications
Published in Optometry and vision science (01-12-2010)“…The human retina is a uniquely accessible tissue. Tools like scanning laser ophthalmoscopy and spectral domain-optical coherence tomography provide clinicians…”
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OCT Angiography and Cone Photoreceptor Imaging in Geographic Atrophy
Published in Investigative ophthalmology & visual science (01-12-2018)“…To compare cone spacing and choriocapillaris (CC) perfusion adjacent to geographic atrophy (GA) in patients with age-related macular degeneration (AMD) and…”
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Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation
Published in eLife (25-04-2024)“…Retinitis pigmentosa (RP), a heterogenous group of inherited retinal disorder, causes slow progressive vision loss with no effective treatments available…”
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Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function
Published in JAMA neurology (01-10-2014)“…The identification of a patient with a rare form of severe dysbetalipoproteinemia allowed the study of the consequences of total absence of apolipoprotein E…”
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Col4a1 mutations cause progressive retinal neovascular defects and retinopathy
Published in Scientific reports (27-01-2016)“…Mutations in collagen, type IV, alpha 1 (COL4A1), a major component of basement membranes, cause multisystem disorders in humans and mice. In the eye, these…”
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Retinal End Points for ATXN7-Related Spinocerebellar Ataxia
Published in JAMA ophthalmology (01-04-2024)Get more information
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Expanding the phenotype of TTLL5-associated retinal dystrophy: a case series
Published in Orphanet journal of rare diseases (01-04-2022)“…Inherited retinal dystrophies describe a heterogeneous group of retinal diseases that lead to the irreversible degeneration of rod and cone photoreceptors and…”
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Promises and pitfalls of evaluating photoreceptor-based retinal disease with adaptive optics scanning light ophthalmoscopy (AOSLO)
Published in Progress in retinal and eye research (01-07-2021)“…Adaptive optics scanning light ophthalmoscopy (AOSLO) allows visualization of the living human retina with exquisite single-cell resolution. This technology…”
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The reliability of parafoveal cone density measurements
Published in British journal of ophthalmology (01-08-2014)“…Adaptive optics scanning light ophthalmoscopy (AOSLO) enables direct visualisation of the cone mosaic, with metrics such as cone density and cell spacing used…”
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Correlation of Serial Scleral and Corneal Pneumatonometry
Published in Ophthalmology (Rochester, Minn.) (01-09-2015)“…Purpose To evaluate the usefulness of scleral pneumatonometry as an alternative for corneal measurements of intraocular pressure (IOP) over a broad range of…”
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Coding and non-coding variants in the ciliopathy gene CFAP410 cause early-onset non-syndromic retinal degeneration
Published in Npj genomic medicine (08-11-2024)“…Inherited retinal degenerations are blinding genetic disorders characterized by high genetic and phenotypic heterogeneity. In this retrospective study, we…”
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Discordant anatomical, electrophysiological, and visual behavioral profiles of retinal degeneration in rat models of retinal degenerative disease
Published in Investigative ophthalmology & visual science (14-09-2012)“…To assess structural, functional, and visual behavioral relationships in mutant rhodopsin transgenic (Tg) rats and to determine whether early optokinetic…”
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Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps
Published in Translational vision science & technology (18-07-2018)Get full text
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