Search Results - "Dunaway, Keith W"
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Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex
Published in Nature communications (24-04-2018)“…Rhythmic oscillations of physiological processes depend on integrating the circadian clock and diurnal environment. DNA methylation is epigenetically…”
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Phosphorylation of Distinct Sites in MeCP2 Modifies Cofactor Associations and the Dynamics of Transcriptional Regulation
Published in Molecular and Cellular Biology (01-07-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes
Published in Genome medicine (14-10-2020)“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the…”
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Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes
Published in Cell reports (Cambridge) (13-12-2016)“…Rare variants enriched for functions in chromatin regulation and neuronal synapses have been linked to autism. How chromatin and DNA methylation interact with…”
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A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies
Published in Epigenetics (04-03-2017)“…DNA methylation is an epigenetic mark at the interface of genetic and environmental factors relevant to human disease. Quantitative assessments of global DNA…”
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Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches
Published in Epigenetics (04-03-2018)“…Augmented maternal care during the first postnatal week promotes life-long stress resilience and improved memory compared with the outcome of routine rearing…”
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MeCP2 modulates gene expression pathways in astrocytes
Published in Molecular autism (25-01-2013)“…Mutations in MECP2 encoding methyl-CpG-binding protein 2 (MeCP2) cause the X-linked neurodevelopmental disorder Rett syndrome. Rett syndrome patients exhibit…”
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Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
Published in Human molecular genetics (15-08-2019)“…DNA methylation acts at the interface of genetic and environmental factors relevant for autism spectrum disorder (ASD). Placenta, normally discarded at birth,…”
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15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain
Published in Human molecular genetics (15-11-2011)“…Copy number variations (CNVs) within human 15q11.2-13.3 show reduced penetrance and variable expressivity in a range of neurologic disorders. Therefore,…”
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Investigation of modifier genes within copy number variations in Rett syndrome
Published in Journal of human genetics (01-07-2011)Get full text
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Investigation of modifier genes within copy number variations in Rett syndrome
Published in Journal of human genetics (01-07-2011)“…MECP2 mutations are responsible for two different phenotypes in females, classical Rett syndrome and the milder Zappella variant (Z-RTT). We investigated…”
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Erratum: Investigation of modifier genes within copy number variations in Rett syndrome
Published in Journal of human genetics (25-05-2012)“…Correction to: Journal of Human Genetics 2011, 56(7): 508–515; doi:10.1038/jhg.2011.50; published online 19 May 2011. After the publication of the article, the…”
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