Search Results - "Dunachie, Susanna J"

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera by Zhou, Daming, Dejnirattisai, Wanwisa, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, Paesen, Guido C., Lopez-Camacho, Cesar, Slon-Campos, Jose, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin, Charlton, Sue, Walter, Thomas S., Skelly, Donal, Lumley, Sheila F., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, James, William, Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began when the first sequence was published, and this forms…”
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Potent cross-reactive antibodies following Omicron breakthrough in vaccinees by Nutalai, Rungtiwa, Zhou, Daming, Tuekprakhon, Aekkachai, Ginn, Helen M., Supasa, Piyada, Liu, Chang, Huo, Jiandong, Mentzer, Alexander J., Duyvesteyn, Helen M.E., Dijokaite-Guraliuc, Aiste, Skelly, Donal, Ritter, Thomas G., Amini, Ali, Bibi, Sagida, Adele, Sandra, Johnson, Sile Ann, Constantinides, Bede, Webster, Hermione, Temperton, Nigel, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Crook, Derrick, Pollard, Andrew J., Lambe, Teresa, Goulder, Philip, Paterson, Neil G., Williams, Mark A., Hall, David R., Mongkolsapaya, Juthathip, Fry, Elizabeth E., Dejnirattisai, Wanwisa, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…Highly transmissible Omicron variants of SARS-CoV-2 currently dominate globally. Here, we compare neutralization of Omicron BA.1, BA.1.1, and BA.2. BA.2 RBD…”
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The association between temperature, rainfall and humidity with common climate-sensitive infectious diseases in Bangladesh by Chowdhury, Fazle Rabbi, Ibrahim, Quazi Shihab Uddin, Bari, Md Shafiqul, Alam, M M Jahangir, Dunachie, Susanna J, Rodriguez-Morales, Alfonso J, Patwary, Md Ismail

“…Bangladesh is one of the world's most vulnerable countries for climate change. This observational study examined the association of temperature, humidity and…”
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Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy by Ragonnet-Cronin, Manon, Nutalai, Rungtiwa, Huo, Jiandong, Dijokaite-Guraliuc, Aiste, Das, Raksha, Tuekprakhon, Aekkachai, Supasa, Piyada, Liu, Chang, Selvaraj, Muneeswaran, Groves, Natalie, Hartman, Hassan, Ellaby, Nicholas, Mark Sutton, J., Bahar, Mohammad W., Zhou, Daming, Fry, Elizabeth, Ren, Jingshan, Brown, Colin, Klenerman, Paul, Dunachie, Susanna J., Mongkolsapaya, Juthathip, Hopkins, Susan, Chand, Meera, Stuart, David I., Screaton, Gavin R., Rokadiya, Sakib

“…COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal antibodies (mAbs). To minimise virus escape from neutralisation these…”
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Role of Burkholderia pseudomallei-Specific IgG2 in Adults with Acute Melioidosis, Thailand by Chaichana, Panjaporn, Jenjaroen, Kemajittra, Chumseng, Suchintana, Sumonwiriya, Manutsanun, Rongkard, Patpong, Kronsteiner, Barbara, Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P J, Chantratita, Narisara, Dunachie, Susanna J

“…Melioidosis is a life-threatening infectious disease caused by the gram-negative bacillus Burkholderia pseudomallei. An effective vaccine is needed, but data…”
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The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86 by Zhou, Daming, Supasa, Piyada, Liu, Chang, Dijokaite-Guraliuc, Aiste, Duyvesteyn, Helen M. E., Selvaraj, Muneeswaran, Mentzer, Alexander J., Das, Raksha, Dejnirattisai, Wanwisa, Temperton, Nigel, Klenerman, Paul, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…Under pressure from neutralising antibodies induced by vaccination or infection the SARS-CoV-2 spike gene has become a hotspot for evolutionary change, leading…”
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Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection by Liu, Chang, Das, Raksha, Dijokaite-Guraliuc, Aiste, Zhou, Daming, Mentzer, Alexander J., Supasa, Piyada, Selvaraj, Muneeswaran, Duyvesteyn, Helen M. E., Ritter, Thomas G., Temperton, Nigel, Klenerman, Paul, Dunachie, Susanna J., Paterson, Neil G., Williams, Mark A., Hall, David R., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.

“…The rapid evolution of SARS-CoV-2 is driven in part by a need to evade the antibody response in the face of high levels of immunity. Here, we isolate spike (S)…”
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Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis by Pumpuang, Apinya, Dunachie, Susanna J, Phokrai, Phornpun, Jenjaroen, Kemajittra, Sintiprungrat, Kitisak, Boonsilp, Siriphan, Brett, Paul J, Burtnick, Mary N, Chantratita, Narisara

“…Melioidosis is a severe disease caused by Burkholderia pseudomallei. Clinical manifestations are diverse and acute infections require immediate treatment with…”
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A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus by Inthawong, Manutsanun, Pinthong, Nattapon, Thaiprakhong, Areerat, Wangrangsimakul, Tri, Sunyakumthorn, Piyanate, Hill, Jennifer, Sonthayanon, Piengchan, Paris, Daniel H, Dunachie, Susanna J, Kronsteiner, Barbara

“…Assessment of cellular immune responses by combining intracellular cytokine staining and immunophenotyping using flow cytometry enables the simultaneous…”
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Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand by Rongkard, Patpong, Kronsteiner, Barbara, Hantrakun, Viriya, Jenjaroen, Kemajittra, Sumonwiriya, Manutsanun, Chaichana, Panjaporn, Chumseng, Suchintana, Chantratita, Narisara, Wuthiekanun, Vanaporn, Fletcher, Helen A, Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P.J, Dunachie, Susanna J

“…Melioidosis is a neglected tropical disease with an estimated annual mortality rate of 89,000 in 45 countries across tropical regions. The causative agent is…”
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Deciphering the human antibody response against Burkholderia pseudomallei during melioidosis using a comprehensive immunoproteome approach by Wagner, Gabriel E, Stanjek, Thomas Franz Paul, Albrecht, Dirk, Lipp, Michaela, Dunachie, Susanna J, Föderl-Höbenreich, Esther, Riedel, Katharina, Kohler, Anne, Steinmetz, Ivo, Kohler, Christian

“…The environmental bacterium causes the often fatal and massively underreported infectious disease melioidosis. Antigens inducing protective immunity in…”
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T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients by Jenjaroen, Kemajittra, Chumseng, Suchintana, Sumonwiriya, Manutsanun, Ariyaprasert, Pitchayanant, Chantratita, Narisara, Sunyakumthorn, Piyanate, Hongsuwan, Maliwan, Wuthiekanun, Vanaporn, Fletcher, Helen A, Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P J, Dunachie, Susanna J

“…Melioidosis is an increasingly recognised cause of sepsis and death across South East Asia and Northern Australia, caused by the bacterium Burkholderia…”
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Immune response to recombinant Burkholderia pseudomallei FliC by Koosakulnirand, Sirikamon, Phokrai, Phornpun, Jenjaroen, Kemajittra, Roberts, Rosemary A, Utaisincharoen, Pongsak, Dunachie, Susanna J, Brett, Paul J, Burtnick, Mary N, Chantratita, Narisara

“…Burkholderia pseudomallei is a flagellated Gram-negative bacterium which is the causative agent of melioidosis. The disease poses a major public health problem…”
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Antibodies in Melioidosis: The Role of the Indirect Hemagglutination Assay in Evaluating Patients and Exposed Populations by Chaichana, Panjaporn, Jenjaroen, Kemajittra, Amornchai, Premjit, Chumseng, Suchintana, Langla, Sayan, Rongkard, Patpong, Sumonwiriya, Manutsanun, Jeeyapant, Atthanee, Chantratita, Narisara, Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P J, Wuthiekanun, Vanaporn, Dunachie, Susanna J

“…Melioidosis is a major neglected tropical disease with high mortality, caused by the Gram-negative bacterium ( ). Microbiological culture remains the gold…”
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A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model by Inthawong, Manutsanun, Sunyakumthorn, Piyanate, Wongwairot, Sirima, Anantatat, Tippawan, Dunachie, Susanna J, Im-Erbsin, Rawiwan, Jones, James W, Mason, Carl J, Lugo, Luis A, Blacksell, Stuart D, Day, Nicholas P J, Sonthayanon, Piengchan, Richards, Allen L, Paris, Daniel H

“…Scrub typhus is a vector-borne febrile illness caused by Orientia tsutsugamushi transmitted by the bite of Trombiculid mites. O. tsutsugamushi has a high…”
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Impact of shipping temperature on cell viability and T cell responses to bacterial antigens by Rongkard, Patpong, Dunachie, Susanna J, Kronsteiner, Barbara

“…Interferon-γ (IFN-γ) secretion by T cells is a key correlate of immune protection against many pathogens including tuberculosis and the neglected tropical…”
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Correction: A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model by Inthawong, Manutsanun, Sunyakumthorn, Piyanate, Wongwairot, Sirima, Anantatat, Tippawan, Dunachie, Susanna J, Im-Erbsin, Rawiwan, Jones, James W, Mason, Carl J, Lugo, Luis A, Blacksell, Stuart D, Day, Nicholas P J, Sonthayanon, Piengchan, Richards, Allen L, Paris, Daniel H

“…[This corrects the article DOI: 10.1371/journal.pntd.0010611.]…”
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Melioidosis DS rapid test: A standardized serological dipstick assay with increased sensitivity and reliability due to multiplex detection by Wagner, Gabriel E, Föderl-Höbenreich, Esther, Assig, Karoline, Lipp, Michaela, Berner, Andreas, Kohler, Christian, Lichtenegger, Sabine, Stiehler, Julia, Karoonboonyanan, Wisansanee, Thanapattarapairoj, Nida, Promkong, Chidchanok, Koosakulnirand, Sirikamon, Chaichana, Panjaporn, Ehricht, Ralf, Gad, Anne-Marie, Söffing, Hans H, Dunachie, Susanna J, Chantratita, Narisara, Steinmetz, Ivo

“…Melioidosis, caused by Burkholderia pseudomallei, is a severe infectious disease with high mortality rates, but is under-recognized worldwide. In endemic…”
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Rapid and Sensitive Multiplex Detection of Burkholderia pseudomallei-Specific Antibodies in Melioidosis Patients Based on a Protein Microarray Approach by Kohler, Christian, Dunachie, Susanna J, Müller, Elke, Kohler, Anne, Jenjaroen, Kemajittra, Teparrukkul, Prapit, Baier, Vico, Ehricht, Ralf, Steinmetz, Ivo

“…The environmental bacterium Burkholderia pseudomallei causes the infectious disease melioidosis with a high case-fatality rate in tropical and subtropical…”
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Immunogenicity of Abdala COVID-19 vaccine in Vietnamese people after primary and booster vaccinations: A prospective observational study in Vietnam by Thanh, Tran Tan, Tu, Nguyen Thi Kha, Nguyet, Lam Anh, Thuy, Cao Thu, Thuan, Nguyen Lam Thai, Ny, Nguyen Thi Han, Nhu, Le Nguyen Truc, Thanh, Le Kim, Hong, Nguyen Thi Thu, Anh, Nguyen To, Truong, Nguyen Thanh, Chau, Nguyen Van Vinh, Yen, Lam Minh, Van E, Phan, Thuong, Nguyen Phong, Van Truc, Nguyen, Trung, Pham Huu, Yap, Wee Chee, Pandey, Rahul, Yee, Sidney, Weng, Ruifen, Mongkolsapaya, Juthathip, Dejnirattisai, Wanwisa, Hamers, Raph L, Chantratita, Narisara, Screaton, Gavin, Dunachie, Susanna J, Jones, E Yvonne, Stuart, David I, Dung, Nguyen Thanh, Thwaites, Guy, Wang, Lin-Fa, Tan, Chee Wah, Tan, Le Van

“…•Abdala COVID-19 vaccine is immunogenic in Vietnamese people.•Antibodies obtained after primary series were comparable with that of ChAdOx1-S.•Antibodies…”
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