Search Results - "Dumon, J. C."

Extracellular calcium downregulates estrogen receptor alpha and increases its transcriptional activity through calcium-sensing receptor in breast cancer cells by Journé, F, Dumon, J.-C, Kheddoumi, N, Fox, J, Laı̈os, I, Leclercq, G, Body, J.-J

“…Skeleton is the most common organ targeted by breast cancer cells, especially from estrogen receptor alpha (ER)-positive neoplasms. Metastatic cells can…”
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Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells by JOURNE, F, CHABOTEAUX, C, DUMON, J-C, LECLERCQ, G, LAURENT, G, BODY, J-J

“…Tamoxifen is the standard first-line endocrine therapy for breast cancer, but recent data indicate that it is likely to be replaced by the effective aromatase…”
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Study of Annual and Seasonal Dissolved Inorganic Nitrogen Inputs into the Arcachon Lagoon, Atlantic Coast (France) by Rimmelin, P., Dumon, J.-C., Maneux, E., GonÇalves, A.

“…The aim of this study is to determine, by applying a direct method, dissolved inorganic nitrogen (DIN) inputs which reach a coastal lagoon: the Arcachon Bay…”
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A novel MVMp-based vector system specifically designed to reduce the risk of replication-competent virus generation by homologous recombination by DUPONT, F, KARIM, A, DUMON, J-C, MINE, N, AVALOSSE, B

“…Recent work highlights the potential usefulness of MVM-based vectors as selective vehicles for cancer gene therapy (Dupont et al, Gene Therapy, 2000; 7:…”
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Decreased efficacy of bisphosphonates for recurrences of tumor-induced hypercalcemia by BODY, J. J, LOUVIAUX, I, DUMON, J. C

“…Bisphosphonates are now the standard treatment for tumor-induced hypercalcemia (TIH), and pamidronate can normalize serum Ca in at least 90% of the patients…”
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Comparative evaluation of markers of bone resorption in patients with breast cancer-induced osteolysis before and after bisphosphonate therapy by BODY, J. J, DUMON, J. C, GINEYTS, E, DELMAS, P. D

“…The understanding of the pathophysiology and the monitoring of metastatic bone disease remains unsatisfactory. We compared several new markers of bone turnover…”
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Hypercalcaemia of melanoma: incidence, pathogenesis and therapy with bisphosphonates by des Grottes, J M, Dumon, J C, Body, J J

“…Tumour-induced hypercalcaemia (TIH) is a frequent complication of advanced cancer but has been rarely reported in patients with malignant melanoma, and its…”
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Circulating PTHrP concentrations in tumor‐induced hypercalcemia: Influence on the response to bisphosphonate and changes after therapy by Body, J.J., Dumon, J.C., Thirion, M., Cleeren, A.

“…We studied the influence of circulating parathyroid hormone‐related protein (PTHrP) concentrations on the response of hypercalcemic cancer patients to…”
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Technical and clinical validation of a new immunoradiometric assay for human osteocalcin by DUMON, J. C, WANTIER, H, MATHIEU, F, MANTIA, M, BODY, J. J

“…Dumon JC, Wantier H, Mathieu F, Mantia M, Body JJ, Technical and clinical validation of a new immunoradiometric assay for human osteocalcin. Eur J Endocrinol…”
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Intravenous pamidronate in patients with tumor‐induced osteolysis: A biochemical dose‐response study by Body, J. J., Dumon, J. C., Piccart, M., Ford, J.

“…Bisphosphonates are used increasingly in normocalcemic patients for treating tumor‐induced osteolysis (TIO) but little is known about the metabolic effects and…”
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The bone isoenzyme of alkaline phosphatase in hypercalcaemic cancer patients by Body, J.J., Dumon, J.C., Blocklet, D., Darte, C.

“…Alkaline phosphatase (AP) is the classic marker of bone formation, especially in cancer patients, but the interpretation of its measurement is complicated by…”
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Gene therapy clinical trials in Belgium by Sneyers, M, Dumon, J C, van Vaerenbergh, B, Moens, W

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Atmospheric deposits of dissolved inorganic nitrogen in the southwest of France by RIMMELIN, P, DUMON, J.-C, BURDLOFF, D, MANEUX, E

“…A 1-year study of bulk atmospheric dissolved inorganic nitrogen (DIN) deposits has identified a medium anthropogenic impact in the southwest of France (average…”
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Cyclical pamidronate infusions in postmenopausal osteoporosis by Peretz, Anne, Body, Jean Jacques, Dumon, Jean Claude, Rozenberg, Serge, Hotimski, Anouk, Praet, Jean Philippe, Moris, Muriel, Ham, Humphrey, Bergmann, Pierre

“…Objectives: Until recently, two bisphosphonates, pamidronate (APD) and etidronate were available for clinical purposes. Contrary to etidronate, pamidronate was…”
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Recovery of parathyroid hormone secretion during correction of tumor-associated hypercalcemia by Body, J J, Dumon, J C, Seraj, F, Cleeren, A

“…Spontaneous recovery of parathyroid secretion during correction of tumor-associated hypercalcemia by bisphosphonates provides a unique clinical opportunity to…”
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Circulating calcitonin levels in healthy children and subjects with congenital hypothyroidism from birth to adolescence by Body, J J, Chanoine, J P, Dumon, J C, Delange, F

“…Using an extraction-concentration technique of circulating calcitonin (exCT) that permits a sensitive and specific assessment of circulating CT monomer levels,…”
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Nasal human calcitonin for tumor-induced hypercalcemia by DUMON, J. C, MAGRITTE, A, BODY, J. J

“…We treated four hypercalcemic cancer patients by nasal hCT, 3 x 2 mg daily, which has been reported to be active in Paget's disease at lower doses. Only one…”
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Circulating concentrations of interleukin-6 in cancer patients and their pathogenic role in tumor-induced hypercalcemia by VANDERSCHUEREN, B, DUMON, J. C, OLEFFE, V, HEYMANS, C, GERAIN, J, BODY, J. J

“…Circulating interleukin-6 (IL-6) concentrations correlate with disease activity in severe inflammatory conditions, in sepsis and in some hematological…”
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Treatment of tumour-induced hypercalcaemia with the bisphosphonate pamidronate: dose-response relationship and influence of tumour type by Body, J J, Dumon, J C

“…Patients with humoral hypercalcaemia of malignancy appear to respond less well to biphosphonate therapy than hypercalcaemic patients with osteolytic…”
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Retrobulbar optic neuritis after pamidronate administration in a patient with a history of cutaneous porphyria by des Grottes, J M, Schrooyen, M, Dumon, J C, Body, J J

“…We describe the case of a patient who developed reversible retrobulbar optic neuritis after intravenous pamidronate therapy for established osteoporosis. This…”
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