Search Results - "Dumm, Rebekah"

Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication by Courtney, David G., Kennedy, Edward M., Dumm, Rebekah E., Bogerd, Hal P., Tsai, Kevin, Heaton, Nicholas S., Cullen, Bryan R.

“…Many viral RNAs are modified by methylation of the N6 position of adenosine (m6A). m6A is thought to regulate RNA splicing, stability, translation, and…”
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The Brief Case: Tricky Trichosporon asahii in the urinary tract by Eickhoff, Michaela J, Dumm, Rebekah E

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Development of a scoring system to identify high-yield specimens for bacterial broad-range 16S rRNA gene PCR with sequencing at a tertiary care medical center by Dumm, Rebekah E, Glaser, Laurel J, Rodino, Kyle G

“…Abstract Objectives Broad-range bacterial polymerase chain reaction with sequencing (BRBPS) provides valuable diagnostic data, especially in cases of…”
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A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor by Heaton, Brook E., Kennedy, Edward M., Dumm, Rebekah E., Harding, Alfred T., Sacco, Matthew T., Sachs, David, Heaton, Nicholas S.

“…Influenza A virus (IAV) is a pathogen that poses significant risks to human health. It is therefore critical to develop strategies to prevent influenza…”
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Microbiome-Based Diagnostics for Disease: Where Are We Now and Where Are We Headed? by Yarbrough, Melanie L, Dumm, Rebekah E, Bry, Lynn, Kelly, Brendan J, Schwartz, Drew, Uberoi, Aayushi

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Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance by Fiege, Jessica K, Stone, Ian A, Dumm, Rebekah E, Waring, Barbara M, Fife, Brian T, Agudo, Judith, Brown, Brian D, Heaton, Nicholas S, Langlois, Ryan A

“…Influenza A virus (IAV) is a seasonal pathogen with the potential to cause devastating pandemics. IAV infects multiple epithelial cell subsets in the…”
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The Development and Use of Reporter Influenza B Viruses by Dumm, Rebekah E, Heaton, Nicholas S

“…Influenza B viruses (IBVs) are major contributors to total human influenza disease, responsible for ~1/3 of all infections. These viruses, however, are…”
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Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function by Dumm, Rebekah E., Fiege, Jessica K., Waring, Barbara M., Kuo, Chay T., Langlois, Ryan A., Heaton, Nicholas S.

“…Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown…”
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Closing The Brief Case: A Variant on a Classic-Abiotrophia defectiva Endocarditis with Discitis by Dumm, Rebekah E, Wing, Anna, Richterman, Aaron, Jacob, Jerry, Glaser, Laurel J, Rodino, Kyle G

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The Brief Case: A Variant on a Classic-Abiotrophia defectiva Endocarditis with Discitis by Dumm, Rebekah E, Wing, Anna, Richterman, Aaron, Jacob, Jerry, Glaser, Laurel J, Rodino, Kyle G

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Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs by Harding, Alfred T, Heaton, Brook E, Dumm, Rebekah E, Heaton, Nicholas S

“…Influenza virus vaccine production is currently limited by the ability to grow circulating human strains in chicken eggs or in cell culture. To facilitate…”
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Heterogeneity of Antiviral Responses in the Upper Respiratory Tract Mediates Differential Non-lytic Clearance of Influenza Viruses by Dumm, Rebekah E., Wellford, Sebastian A., Moseman, E. Ashley, Heaton, Nicholas S.

“…Influenza viruses initiate infection in the upper respiratory tract (URT), but early viral tropism and the importance of cell-type-specific antiviral responses…”
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Comparison of Clostridioides difficile nucleic acid amplification test (NAAT) results using fresh and frozen stool specimens and rectal swabs by Dumm, Rebekah E, Burnham, Carey-Ann D, Hink, Tiffany, Reske, Kimberly A, Struttmann, Emily, Iqbal, Zainab Hassan, Cass, Candice, Kwon, Jennie H, Olsen, Margaret A, Dubberke, Erik R

“…Nucleic acid amplification tests (NAATs) are frequently used in research and diagnostic testing, but the effect of freezing specimens on NAAT performance is…”
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Thiol-ene Photocrosslinking of Cytocompatible Resilin-Like Polypeptide-PEG Hydrogels by McGann, Christopher L., Dumm, Rebekah E., Jurusik, Anna K., Sidhu, Ishnoor, Kiick, Kristi L.

“…A range of chemical strategies have been used for crosslinking recombinant polypeptide hydrogels, although only a few have employed photocrosslinking…”
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Colonization with extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) in healthcare and community settings in Botswana: an antibiotic resistance in communities and hospitals (ARCH) study by Mannathoko, Naledi, Mosepele, Mosepele, Gross, Robert, Smith, Rachel M., Alby, Kevin, Glaser, Laurel, Richard-Greenblatt, Melissa, Dumm, Rebekah, Sharma, Aditya, Jaskowiak-Barr, Anne, Cressman, Leigh, Sewawa, Kgotlaetsile, Cowden, Laura, Reesey, Emily, Otukile, Dimpho, Paganotti, Giacomo M., Mokomane, Margaret, Lautenbach, Ebbing

“…•Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) prevalence was high in hospital, clinic, and community settings.•Carbapenem-resistant…”
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DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection by Chambers, Benjamin S., Heaton, Brook E., Rausch, Keiko, Dumm, Rebekah E., Hamilton, Jennifer R., Cherry, Sara, Heaton, Nicholas S.

“…Despite the cytopathic nature of influenza A virus (IAV) replication, we recently reported that a subset of lung epithelial club cells is able to intrinsically…”
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Implementation of an Extraction-Free COVID Real-Time PCR Workflow in a Pediatric Hospital Setting by Dumm, Rebekah E, Elkan, Michael, Fink, Jeffrey, Richard-Greenblatt, Melissa, Obstfeld, Amrom E, Harris, Rebecca M

“…This study outlines the development, implementation, and impact of a laboratory-developed, extraction-free real-time PCR assay as the primary diagnostic test…”
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Clinical Utility of Metagenomic Next-Generation Sequencing of Plasma Microbial Cell-Free DNA: a Single-Center Retrospective Study by Almeida, Guilherme Gomide, Dumm, Rebekah

“…Abstract Infectious diseases account for significant morbidity and mortality in healthcare, and metagenomic next-generation sequencing of plasma microbial…”
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Implementation, Optimization, and Stewardship of Advanced Molecular Testing for Infectious Diseases by Azimi, Vahid, Dumm, Rebekah E.

“…Advanced molecular testing for infectious diseases is complex and results can be strongly influenced by testing methodology, specimen selection and patient…”
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664. Clinical Impact of Cell-Free DNA Metagenomics in Diagnosing Infectious Diseases in Pediatrics: A Single-Center Experience by Otto, William, Dumm, Rebekah, Fatemi, Yasaman, Swami, Sanjeev K

“…Abstract Background Metagenomic next-generation sequencing (mNGS) of plasma cell-free DNA has significant potential to improve infectious diseases diagnostics…”
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