Search Results - "Dumesnil, Anais"
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Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction
Published in Circulation (New York, N.Y.) (12-04-2016)“…BACKGROUND—The lymphatic system regulates interstitial tissue fluid balance, and lymphatic malfunction causes edema. The heart has an extensive lymphatic…”
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Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction
Published in Arteriosclerosis, thrombosis, and vascular biology (01-07-2020)“…OBJECTIVE:Lymphatics play an essential pathophysiological role in promoting fluid and immune cell tissue clearance. Conversely, immune cells may influence…”
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Short‐ and long‐term administration of the non‐steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome‐related cardio‐renal dysfunction
Published in Diabetes, obesity & metabolism (01-10-2018)“…Aim To determine whether non‐steroidal mineralocorticoid receptor (MR) antagonists oppose metabolic syndrome‐related end‐organ, i.e. cardiac, damage. Materials…”
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A 30-Minute Supraceliac Aortic Clamping in the Rat Causes Death Due to an Inflammatory Response and Pulmonary Lesions
Published in Annals of vascular surgery (01-10-2018)“…The treatment of thoracoabdominal aortic aneurysms through an open approach has general and pulmonary consequences of multiple etiologies. Our assumption was…”
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Role of M2-like macrophage recruitment during angiogenic growth factor therapy
Published in Angiogenesis (London) (01-04-2015)“…Therapeutic angiogenesis has yet to fulfill its promise for the clinical treatment of ischemic diseases. Given the impact of macrophages during…”
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The IL-1β Antibody Gevokizumab Limits Cardiac Remodeling and Coronary Dysfunction in Rats With Heart Failure
Published in JACC. Basic to translational science (01-08-2017)“…Visual Abstract…”
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Lebetin 2, a Snake Venom-Derived B-Type Natriuretic Peptide, Provides Immediate and Prolonged Protection against Myocardial Ischemia-Reperfusion Injury via Modulation of Post-Ischemic Inflammatory Response
Published in Toxins (10-09-2019)“…Myocardial infarction (MI) followed by left ventricular (LV) remodeling is the most frequent cause of heart failure. Lebetin 2 (L2), a snake venom-derived…”
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Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction
Published in ESC Heart Failure (01-04-2021)“…Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by…”
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Ezh2 emerges as an epigenetic checkpoint regulator during monocyte differentiation limiting cardiac dysfunction post-MI
Published in Nature communications (25-07-2023)“…Epigenetic regulation of histone H3K27 methylation has recently emerged as a key step during alternative immunoregulatory M2-like macrophage polarization;…”
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Priming of Cardiopulmonary Bypass with Human Albumin Decreases Endothelial Dysfunction after Pulmonary Ischemia-Reperfusion in an Animal Model
Published in International journal of molecular sciences (11-08-2022)“…The routine use of mechanical circulatory support during lung transplantation (LTx) is still controversial. The use of prophylactic human albumin (HA) or…”
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Protein tyrosine phosphatase 1B inactivation limits aging-associated heart failure in mice
Published in American journal of physiology. Heart and circulatory physiology (01-06-2018)“…We have previously shown that protein tyrosine phosphatase 1B (PTP1B) inactivation in mice [PTP1B-deficient (PTP1B ) mice] improves left ventricular (LV)…”
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Cardiopulmonary bypass increases endothelial dysfunction after pulmonary ischaemia-reperfusion in an animal model
Published in European journal of cardio-thoracic surgery (08-05-2021)“…Abstract OBJECTIVES Endothelial dysfunction during ischaemia-reperfusion (IR) is a major cause of primary graft dysfunction during lung transplantation. The…”
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Mineralocorticoid receptor blockade with finerenone improves heart function and exercise capacity in ovariectomized mice
Published in ESC Heart Failure (01-06-2021)“…Aims In post‐menopausal women, incidence of heart failure with preserved ejection fraction is higher than in men. Hormonal replacement therapies did not…”
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Subtotal Nephrectomy Associated with a High-Phosphate Diet in Rats Mimics the Development of Calcified Aortic Valve Disease Associated with Chronic Renal Failure
Published in Journal of clinical medicine (01-02-2023)“…This study addressed the hypothesis that subtotal nephrectomy associated with a high-phosphorus diet (5/6Nx + P) in rats represents a suitable animal model to…”
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Impact of soluble epoxide hydrolase inhibition on early kidney damage in hyperglycemic overweight mice
Published in Prostaglandins & other lipid mediators (01-07-2015)“…•This study shows that sEH inhibition prevents the development of renal dysfunction in hyperglycemic overweight mice beyond its hypoglycemic effect.•sEH…”
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A Supraceliac Aortic Cross Clamping Model to Explore Remote Lung Injury and the Endothelial Glycocalyx
Published in Annals of vascular surgery (01-07-2023)“…We hypothesized that supraceliac aortic cross clamping could induce lung injury mediated by an inflammatory ischemia-reperfusion (IR) trigger. We aimed to…”
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Impact of high-fat diet and vitamin D 3 supplementation on aortic stenosis establishment in waved-2 epidermal growth factor receptor mutant mice
Published in Journal of integrative medicine (01-03-2019)“…The use of animal models of aortic stenosis (AS) remains essential to further elucidate its pathophysiology and to evaluate new therapeutic strategies. The…”
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Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure
Published in Cardiovascular research (31-03-2023)“…Lymphatics are essential for cardiac health, and insufficient lymphatic expansion (lymphangiogenesis) contributes to development of heart failure (HF) after…”
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Endothelium-Specific Deficiency of Polycystin-1 Promotes Hypertension and Cardiovascular Disorders
Published in Hypertension (Dallas, Tex. 1979) (12-09-2022)Get full text
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Endothelium-Specific Deficiency of Polycystin-1 Promotes Hypertension and Cardiovascular Disorders
Published in Hypertension (Dallas, Tex. 1979) (01-11-2022)“…Background: Autosomal dominant polycystic kidney disease is the most frequent hereditary kidney disease and is generally due to mutations in PKD1 and PKD2 ,…”
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