Search Results - "Dumesic, D.A"

Resistance of Cumulus Cell (CC) mitochondria to stress in vitro as a predictor of oocyte competence during ovarian stimulation for in vitro fertilization (IVF) by Alvarez, J.P, Guedikian, A.A, Hill, D.L, Chazenbalk, G.D, Dumesic, D.A

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Immunological, structural and stem cell characteristics of subcutaneous (SC) abdominal adipose in lean polycystic ovary syndrome (PCOS) women versus normoandrogenic ovulatory (NL) women by Phan, J, Madrigal, V.K, Guedikian, A, Li, X, Dumesic, D.A, Chazenbalk, G.D

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Abnormal expression of genes governing adipogenesis and extracellular matrix (ECM) formation in subcutaneous (SC) abdominal adipose stem cells (ASCs) of lean polycystic ovary syndrome (PCOS) women by Chazenbalk, G.D, Phan, J.D, Madrigal, V, Ding, X, Li, X, Dumesic, D.A

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Structure-function relationships of subcutaneous (SC) abdominal adipocytes with metabolic function in lean polycystic ovary syndrome (PCOS) and normoandrogenic ovulatory women by Dumesic, D.A, Madrigal, V, Ramirez, E, Margolis, D.J, Thomas, A, Grogan, T.R, Chazenbalk, G.D

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Hyperandrogenism is associated with preferential fat deposition of visceral versus subcutaneous (SC) abdominal fat in lean polycystic ovary syndrome (PCOS) women by Akopians, A.L, Madrigal, V, Fisch, S, Ramirez, E, Margolis, D, Sarma, M.K, Thomas, M.A, Grogan, T, Abbott, D.H, Haykal, R, Chazenbalk, G.D, Dumesic, D.A

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The ratio of follicle fluid (FF) cortisol level to cumulus cell (CC) lipid content is elevated with clinical pregnancy following ovarian stimulation for in vitro fertilization (IVF) by Simerman, A.A, Amin, M.B, Hill, D.L, Abbott, D.H, Chazenbalk, G.D, Dumesic, D.A

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Mineralocorticoid production by mural granulosa cells (MGCs) as a modulator of steroidogenesis during ovarian stimulation for in vitro fertilization (IVF) by Amin, M, Singh, P, Briton-Jones, C, Hill, D.L, Chazenbalk, G, Dumesic, D.A

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Cortisol may promote cumulus cell (CC) lipid utilization as an energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization (IVF) by Simerman, A.A, Hill, D.L, Goldstein, E, Grogan, T, Elashoff, D, Manrriquez, A.N, Clarke, N.J, Chazenbalk, G.D, Dumesic, D.A

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Testosterone inhibits subcutaneous abdominal adipogenesis during adipose stem cell differentiation to preadipocytes by Chazenbalk, G, Irge, D, Shah, A, Dumesic, D.A

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Intrafollicular anti-mullerian hormone (AMH) levels positively correlate with follicle sensitivity to follicle stimulating hormone (FSH) and are elevated in polycystic ovary syndrome (PCOS) by Dumesic, D.A, Lesnick, T.G, Booher, J, Wong, A, Ball, G.D, Abbott, D.H

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Clustering of PCOS-like traits in naturally hyperandrogenic female rhesus monkeys by Abbott, D.H., Rayome, B.H., Dumesic, D.A., Lewis, K.C., Edwards, A.K., Wallen, K., Wilson, M.E., Appt, S.E., Levine, J.E.

“…Abstract STUDY QUESTION Do naturally occurring, hyperandrogenic (≥1 SD of population mean testosterone, T) female rhesus monkeys exhibit traits typical of…”
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Increased follicle recruitment and testosterone-related adiposity contribute to granulosa cell dysfunction in lean polycystic ovary syndrome (PCOS) women by Guedikian, A., Lee, A.Y., Grogan, T.R., Abbott, D.H., Largaespada, K., Chazenbalk, G.D., Dumesic, D.A.

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Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits by Abbott, David H, Levine, Jon E, Dumesic, Daniel A

“…Genetics-based studies of women with polycystic ovary syndrome (PCOS) implicate >20 PCOS risk genes that collectively account for <10% of PCOS. Clinicians now…”
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Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome? by Abbott, D.H., Barnett, D.K., Bruns, C.M., Dumesic, D.A.

“…The aetiology of polycystic ovary syndrome (PCOS) remains unknown. This familial syndrome is prevalent among reproductive-aged women and its inheritance…”
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Early prenatal androgenization results in diminished ovarian reserve in adult female rhesus monkeys by Dumesic, D.A., Patankar, M.S., Barnett, D.K., Lesnick, T.G., Hutcherson, B.A., Abbott, D.H.

“…BACKGROUND Early prenatal androgenization (PA) accelerates follicle differentiation and impairs embryogenesis in adult female rhesus monkeys (Macaca mulatta)…”
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Prenatal androgen excess negatively impacts body fat distribution in a nonhuman primate model of polycystic ovary syndrome by Bruns, C.M, Baum, S.T, Colman, R.J, Dumesic, D.A, Eisner, J.R, Jensen, M.D, Whigham, L.D, Abbott, D.H

“…Introduction: Prenatally androgenized (PA) female rhesus monkeys share metabolic abnormalities in common with polycystic ovary syndrome (PCOS) women. Early…”
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Nonhuman primates contribute unique understanding to anovulatory infertility in women by Abbott, D.H, Foong, S.C, Barnett, D.K, Dumesic, D.A

“…Anovulatory infertility affects a large proportion of reproductive-aged women. Major improvements in successful clinical treatment of this prevalent disorder…”
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