Search Results - "Dumenil, D"

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis by Bond, Catherine E, McKeone, Diane M, Kalimutho, Murugan, Bettington, Mark L, Pearson, Sally-Ann, Dumenil, Troy D, Wockner, Leesa F, Burge, Matthew, Leggett, Barbara A, Whitehall, Vicki L J

“…Serrated pathway colorectal cancers (CRCs) are characterised by a BRAF mutation and half display microsatellite instability (MSI). The Wnt pathway is commonly…”
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Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue by Dumenil, Troy D., Wockner, Leesa F., Bettington, Mark, McKeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A., Whitehall, Vicki L.J.

“…Formalin fixation and embedding of clinical tissue samples in paraffin is a common method for archiving biological material. These samples are often well…”
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Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype by Whitehall, V L J, Dumenil, T D, McKeone, D M, Bond, C E, Bettington, M L, Buttenshaw, R L, Bowdler, L, Montgomery, G W, Wockner, L F, Leggett, B A

“…The CpG Island Methylator Phenotype (CIMP) is fundamental to an important subset of colorectal cancer; however, its cause is unknown. CIMP is associated with…”
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Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation by Escary, Jean-Louis, Perreau, Jacqueline, Duménil, Dominique, Ezine, Sophie, Brûlet, Philippe

“…Leukaemia inhibitory factor (LIF) has a variety of effects on different cell types in vitro, inhibiting the differentiation of embryonic stem cells and…”
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Zyxin is up-regulated during megakaryocytic differentiation of human UT-7/c-mpl cells by Decraene, C, Garçon, L, Lacout, C, Sabri, S, Auffray, C, Vainchenker, W, Duménil, D, Piétu, G, Svinartchuk, F

“…To characterize genes involved in megakaryocytic commitment, we compared expression profiles of bipotent cells (UT-7/c-mpl) with those of the same cells…”
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Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells by Weil, D, Garçon, L, Harper, M, Duménil, D, Dautry, F, Kress, M

“…RNA interference, the inhibition of gene expression by double-stranded RNA, provides a powerful tool for functional studies once the sequence of a gene is…”
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Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation by Dubart, A, Feger, F, Lacout, C, Goncalves, F, Vainchenker, W, Dumenil, D

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Protein Kinase C Mediates the Mitogenic Action of Thrombopoietin in c-Mpl–Expressing UT-7 Cells by Hong, Ying, Dumènil, Dominique, van der Loo, Bernd, Goncalves, Frédérique, Vainchenker, William, Erusalimsky, Jorge D.

“…Protein kinase C (PKC) has been implicated in signal transduction events elicited by several hematopoietic growth factors. Thrombopoietin (TPO) is the major…”
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Thrombopoietin Induces Histidine Decarboxylase Gene Expression in c-mpl Transfected UT7 Cells by Pacilio, Maria, Debili, Najet, Arnould, Anne, Machavoine, François, Rolli-Derkinderen, Malvyne, Bodger, Michael, Arock, Michel, Duménil, Dominique, Dy, Michel, Schneider, Elke

“…The leukemic cell line UT7 is endowed with both megakaryocyte and basophil differentiation potential, as judged by its capacity to respond to PMA by displaying…”
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Constitutive Expression of GATA-1 Interferes With the Cell-Cycle Regulation by Dubart, A., Romeo, P.H., Vainchenker, W., Dumenil, D.

“…GATA-1, mainly expressed during erythroid differentiation, has been shown to regulate the genes specifically expressed in the late stages of erythropoiesis and…”
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Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines by GONCALVES, F, LACOUT, C, FEGER, F, COHEN-SOLAL, K, GUICHARD, J, CRAMER, E, VAINCHENKER, W, DUMENIL, D

“…Thrombopoietin (TPO) regulates megakaryocytic (MK) maturation and platelet production. Molecular and cellular mechanisms of the TPO-induced MK differentiation…”
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Pluripotent stem cells constitutively expressing a normal erythropoietin receptor give rise to normal hematopoiesis in lethally irradiated recipient mice by Lacout, C, Dubart, A, Vainchenker, W, Duménil, D

“…The cellular mechanism by which the stem cell differentiates toward an individual myeloid lineage is unknown. To determine whether lineage-specific cytokines…”
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Inhibition of the Erythropoietin-Induced Erythroid Differentiation by Granulocyte-Macrophage Colony-Stimulating Factor in the Human UT-7 Cell Line Is Not Due To a Negative Regulation of the Erythropoietin Receptor by Hermine, O., Dubart, A., Porteux, F., Mayeux, P., Titeux, M., Dumenil, D., Vainchenker, W.

“…The human pluripotent UT-7 cell line is growth factor-dependent for proliferation and differentiation. We have previously shown that (1) granulocyte-macrophage…”
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Infection with a Kirsten-retrovirus can induce a multiplicity of tumorigenic phenotypes in the interleukin-3-dependent FDC-P1 cells by Duménil, D, Neel, H, Lacout, C, Dautry, F

“…The identification of ras oncogenes in both human and animal tumors as well as in preleukemic and precancerous lesions suggests that activated ras genes…”
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ETO2 coordinates cellular proliferation and differentiation during erythropoiesis by Goardon, Nicolas, Lambert, Julie A, Rodriguez, Patrick, Nissaire, Philippe, Herblot, Sabine, Thibault, Pierre, Dumenil, Dominique, Strouboulis, John, Romeo, Paul‐Henri, Hoang, Trang

“…The passage from proliferation to terminal differentiation is critical for normal development and is often perturbed in malignancies. To define the molecular…”
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Ectopic expression of the erythropoietin receptor in a murine interleukin-6-dependent plasmacytoma cell line (TEPC-2027) confers proliferative responsiveness to erythropoietin by FEGER, F, DUBART, A, LACOUT, C, DUSANTER-FOURT, I, MAYEUX, P, VAINCHENKER, W, DUMENIL, D

“…To compare the signal transduction pathways used by erythropoietin (Epo) and interleukin-6 (IL-6), the cDNA for the murine Epo receptor (Epo-R) was introduced…”
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Mock retroviral infection alters the developmental potential of murine bone marrow stem cells by Dumenil, D, Jacquemin-Sablon, H, Neel, H, Frindel, E, Dautry, F

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Further studies on the biological activities of the CFU-S inhibitory tetrapeptide AcSDKP. II. Unresponsiveness of isolated adult rat hepatocytes, 3T3, FDC-P2, and K562 cell lines to AcSDKP. Possible involvement of intermediary cell(s) in the mechanism of AcSDKP action by Lauret, E, Dumenil, D, Miyanomae, T, Sainteny, F

“…Because the molecular mechanisms of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP; an inhibitor of spleen colony-forming unit [CFU-S] DNA synthesis) are…”
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Effects of various treatments of CFU-S seeding efficiency in mice by Dumenil, D, Lauret, E, Frindel, E

“…Stem cell seeding efficiency and the proportion of CFU-S in the S phase after cytosine arabinoside (Ara C) treatments were assessed. We found no difference in…”
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Specific Globin mRNAs in Human Erythroleukemia (K562) Cells by Miller, Carl W., Young, Katherine, Dumenil, Domnique, Alter, Blanche P., Schofield, J.Matthew, Bank, Arthur

“…Specific globin mRNA accumulation was quantitated in several lines of K562 cells in the absence and the presence of hemin. Using specific cloned DNA probes,…”
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