Search Results - "Dumas, Patrick"
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Generic Chemometric Models for Metabolite Concentration Prediction Based on Raman Spectra
Published in Sensors (Basel, Switzerland) (26-07-2022)“…Chemometric models for on-line process monitoring have become well established in pharmaceutical bioprocesses. The main drawback is the required calibration…”
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Hybrid deep modeling of a CHO-K1 fed-batch process: combining first-principles with deep neural networks
Published in Frontiers in bioengineering and biotechnology (08-09-2023)“…Introduction: Hybrid modeling combining First-Principles with machine learning is becoming a pivotal methodology for Biopharma 4.0 enactment. Chinese Hamster…”
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Deep hybrid modeling of a HEK293 process: Combining long short-term memory networks with first principles equations
Published in Biotechnology and bioengineering (01-05-2024)“…The combination of physical equations with deep learning is becoming a promising methodology for bioprocess digitalization. In this paper, we investigate for…”
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Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Published in Bioprocess and biosystems engineering (01-11-2022)“…Flux balance analysis (FBA) is currently the standard method to compute metabolic fluxes in genome-scale networks. Several FBA extensions employing diverse…”
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Time Integrated Flux Analysis: Exploiting the Concentration Measurements Directly for Cost-Effective Metabolic Network Flux Analysis
Published in Microorganisms (Basel) (27-11-2019)“…Flux analyses, such as Metabolic Flux Analysis (MFA), Flux Balance Analysis (FBA), Flux Variability Analysis (FVA) or similar methods, can provide insights…”
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Engineering the hard–soft tissue interface with random-to-aligned nanofiber scaffolds
Published in Nanobiomedicine (01-01-2018)“…Tendon injuries can be difficult to heal and have high rates of relapse due to stress concentrations caused by scar formation and the sutures used in surgical…”
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Cannabis use correlates with schizotypal personality traits in healthy students
Published in Psychiatry research (31-01-2002)“…The literature suggests that cannabis use and schizotypal traits both constitute risk factors for the later development of schizophrenia. However, their…”
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Visual pointing and speed / accuracy trade-off in schizophrenia
Published in Cognitive neuropsychiatry (01-05-2000)“…There is a challenge to understand schizophrenia cognitive deficits in terms of a common unifying hypothesis (i.e., context-processing deficit). We suggest…”
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Familial Creutzfeldt-Jakob disease with extensive degeneration of white matter. Ultrastructure of peripheral nerve
Published in Journal of the neurological sciences (01-01-1983)“…A case of Creutzfeldt-Jakob disease (CJD) in a 52-year-old man is described. At post mortem, extensive involvement of white matter was seen. A few similar…”
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Neuropathies périphériques et hépatite chronique virale C : une association fréquente ?
Published in Gastroentérologie clinique et biologique (01-11-1998)Get full text
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Polyneuropathie des quatre membres en postopératoire d'une péritonite chez un éthylique chronique
Published in Médecine thérapeutique : MT (01-05-1998)Get full text
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