Search Results - "Dullaart, Robin P"

Association of Cholesteryl Ester Transfer Protein Genotypes With CETP Mass and Activity, Lipid Levels, and Coronary Risk by Thompson, Alexander, Di Angelantonio, Emanuele, Sarwar, Nadeem, Erqou, Sebhat, Saleheen, Danish, Dullaart, Robin P. F, Keavney, Bernard, Ye, Zheng, Danesh, John

“…CONTEXT The importance of the cholesteryl ester transfer protein (CETP) pathway in coronary disease is uncertain. Study of CETP genotypes can help better…”
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Prevalence and determinants of non-alcoholic fatty liver disease in lifelines: A large Dutch population cohort by van den Berg, Eline H, Amini, Marzyeh, Schreuder, Tim C M A, Dullaart, Robin P F, Faber, Klaas Nico, Alizadeh, Behrooz Z, Blokzijl, Hans

“…Non-alcoholic fatty liver disease is an increasing health issue that develops rather unnoticed with obesity, type 2 diabetes mellitus and metabolic syndrome…”
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The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation by Ebtehaj, Sanam, Gruppen, Eke G, Parvizi, Mojtaba, Tietge, Uwe J F, Dullaart, Robin P F

“…Functional properties of high density lipoproteins (HDL) are increasingly recognized to play a physiological role in atheroprotection. Type 2 diabetes mellitus…”
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Alcohol Consumption, High-Density Lipoprotein Particles and Subspecies, and Risk of Cardiovascular Disease: Findings from the PREVEND Prospective Study by Kunutsor, Setor K, Bhattacharjee, Atanu, Connelly, Margery A, Bakker, Stephan J L, Dullaart, Robin P F

“…The associations of HDL particle (HDL-P) and subspecies concentrations with alcohol consumption are unclear. We aimed to evaluate the interplay between alcohol…”
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Serum free thiols predict cardiovascular events and all-cause mortality in the general population: a prospective cohort study by Abdulle, Amaal E, Bourgonje, Arno R, Kieneker, Lyanne M, Koning, Anne M, la Bastide-van Gemert, S, Bulthuis, Marian L C, Dijkstra, Gerard, Faber, Klaas Nico, Dullaart, Robin P F, Bakker, Stephan J L, Gans, Reinold O B, Gansevoort, Ron T, Mulder, Douwe J, Pasch, Andreas, van Goor, Harry

“…Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative stress. Since serum free thiols are rapidly oxidized by reactive species,…”
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GlycA, a Pro-Inflammatory Glycoprotein Biomarker, and Incident Cardiovascular Disease: Relationship with C-Reactive Protein and Renal Function by Gruppen, Eke G, Riphagen, Ineke J, Connelly, Margery A, Otvos, James D, Bakker, Stephan J L, Dullaart, Robin P F

“…GlycA is a novel nuclear magnetic resonance spectroscopy-measured biomarker of systemic inflammation. We determined whether GlycA is associated with incident…”
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Triglyceride-rich lipoprotein and LDL particle subfractions and their association with incident type 2 diabetes: the PREVEND study by Sokooti, Sara, Flores-Guerrero, Jose L, Heerspink, Hiddo J L, Connelly, Margery A, Bakker, Stephan J L, Dullaart, Robin P F

“…Triglyceride-rich lipoproteins particles (TRLP) and low density lipoprotein particles (LDLP) vary in size. Their association with β-cell function is not well…”
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Role of HDL Cholesterol and Estimates of HDL Particle Composition in Future Development of Type 2 Diabetes in the General Population: The PREVEND Study by Abbasi, Ali, Corpeleijn, Eva, Gansevoort, Ron T, Gans, Rijk O. B, Hillege, Hans L, Stolk, Ronald P, Navis, Gerjan, Bakker, Stephan J. L, Dullaart, Robin P. F

“…Background and Aims: High-density lipoproteins (HDLs) may directly stimulate β-cell function and glucose metabolism. We determined the relationships of fasting…”
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Circulating Citrate Is Associated with Liver Fibrosis in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis by Amjad, Waseem, Shalaurova, Irina, Garcia, Erwin, Gruppen, Eke G, Dullaart, Robin P F, DePaoli, Alex M, Jiang, Z Gordon, Lai, Michelle, Connelly, Margery A

“…Nonalcoholic fatty liver disease (NAFLD) is associated with mitochondrial damage. Circulating mitochondrial metabolites may be elevated in NAFLD but their…”
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PCSK9 Inhibition to Reduce Cardiovascular Events by Dullaart, Robin P.F

“…Since the discovery in 2003 that gain-of-function mutations in the gene encoding proprotein convertase subtilisin–kexin type 9 (PCSK9) cause autosomal dominant…”
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Antibody against apolipoprotein-A1, non-alcoholic fatty liver disease and cardiovascular risk: a translational study by Pagano, Sabrina, Bakker, Stephan J. L, Juillard, Catherine, Vossio, Stefania, Moreau, Dimitri, Brandt, Karim J, Mach, François, Dullaart, Robin P. F, Vuilleumier, Nicolas

“…Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a common liver disease increasing cardiovascular disease (CVD) morbidity and mortality…”
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Serum Alkaline Phosphatase and Risk of Incident Cardiovascular Disease: Interrelationship with High Sensitivity C-Reactive Protein by Kunutsor, Setor K, Bakker, Stephan J L, Kootstra-Ros, Jenny E, Gansevoort, Ronald T, Gregson, John, Dullaart, Robin P F

“…Alkaline phosphatase (ALP) has been suggested to be associated with cardiovascular disease (CVD) risk, however, important aspects of the association, such as…”
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Circulating Trimethylamine-N-Oxide Is Elevated in Liver Transplant Recipients by Trillos-Almanza, Maria Camila, Chvatal-Medina, Mateo, Connelly, Margery A, Moshage, Han, TransplantLines Investigators, Bakker, Stephan J L, de Meijer, Vincent E, Blokzijl, Hans, Dullaart, Robin P F

“…Liver transplant recipients (LTRs) have lower long-term survival rates compared with the general population. This underscores the necessity for developing…”
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Circulating total bilirubin and risk of non-alcoholic fatty liver disease in the PREVEND study: observational findings and a Mendelian randomization study by Kunutsor, Setor K., Frysz, Monika, Verweij, Niek, Kieneker, Lyanne M., Bakker, Stephan J. L., Dullaart, Robin P. F.

“…The relationship between circulating total bilirubin and incident non-alcoholic fatty liver disease (NAFLD) is uncertain. We aimed to assess the association of…”
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Both LDL and HDL particle concentrations associate positively with an increased risk of developing microvascular complications in patients with type 2 diabetes: lost protection by HDL (Zodiac-63) by Bourgonje, Arno R, Connelly, Margery A, van Goor, Harry, van Dijk, Peter R, Dullaart, Robin P F

“…Triglyceride-rich lipoproteins (TRL) and low-density lipoproteins (LDL) are associated positively whereas high-density lipoproteins (HDL) are associated…”
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Plasma ApoE elevations are associated with NAFLD: The PREVEND Study by van den Berg, Eline H, Corsetti, James P, Bakker, Stephan J L, Dullaart, Robin P F

“…Non-alcoholic fatty liver disease (NAFLD) is featured by increased plasma very low density lipoproteins (VLDL). The extent to which plasma apolipoprotein E…”
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Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD) by Saeed, Ali, Dullaart, Robin P F, Schreuder, Tim C M A, Blokzijl, Hans, Faber, Klaas Nico

“…Vitamin A is required for important physiological processes, including embryogenesis, vision, cell proliferation and differentiation, immune regulation, and…”
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Cigarette smoking is associated with higher thyroid hormone and lower TSH levels: the PREVEND study by Gruppen, Eke G., Kootstra-Ros, Jenny, Kobold, Anneke Muller, Connelly, Margery A., Touw, Daan, Bos, Jens H. J., Hak, Eelko, Links, Thera P., Bakker, Stephan J. L., Dullaart, Robin P. F.

“…Purpose The extent to which smoking is associated with thyroid stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) when taking…”
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Lipoprotein particle sizes and incident type 2 diabetes: the PREVEND cohort study by Sokooti, Sara, Flores-Guerrero, José L., Heerspink, Hiddo J. L., Garcia, Erwin, Connelly, Margery A., Bakker, Stephan J. L., Dullaart, Robin P. F.

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Serum Level of Cytokeratin 18 (M65) as a Prognostic Marker of High Cardiovascular Disease Risk in Individuals with Non-Alcoholic Fatty Liver Disease by Pagano, Sabrina, Bakker, Stephan J L, Juillard, Catherine, Dullaart, Robin P F, Vuilleumier, Nicolas

“…Alterations in apoptosis, as reflected by circulating Cytokeratin 18 (CK18), are involved in the progression of non-alcoholic fatty liver disease (NAFLD) to…”
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